殷勤

研究副教授 前沿与交叉科学研究院

2009年本科毕业于湖南师范大学,指导教师为李金恒教授。本科毕业后,顺利进入到中科院上海有机化学研究所进行硕博连读,师承游书力研究员,2014年获得博士学位。在攻读博士学位期间一直从事有机小分子和过渡金属不对称催化反应的研究。2014-2017年受德国洪堡奖学金资助,在德国柏林工业大学进行博士后研究工作,合作导师为Martin Oestreich。博士后期间主要从事硼路易斯酸催化主族硅或硼试剂转化方面的研究。

 

2017年6月,加入南方科技大学前沿与交叉科学研究院,与化学系张绪穆教授合作,指导研究生开展工作。以独立或共同通讯作者身份发表11篇论文,包括1篇Chem. Soc. Rec., 2篇J. Am. Chem. Soc., 2 篇Angew. Chem. Int. Ed.,1篇 ACS Catalysis,1篇Chem. Sci.和4篇Org. Lett.。其中包括一篇ESI高被引论文。

迄今为止发表论文超过30篇,包括一作和通讯文章23篇。H-Index为20,总他引次数大于950次。目前主持国家自然科学基金面上和青年项目各1项,深圳市基础研究项目2项。2020年获得广东省自然科学“杰出青年”基金。

个人简介

研究领域

发展高效、高选择性催化剂和策略合成手性功能分子;

廉价金属催化的可持续性化学;

药物分子修饰及活性研究


学术成果 查看更多

迄今为止发表论文超过30篇,包括一作和通讯文章23篇。H-Index为20,总他引次数大于950次。目前主持国家自然科学基金面上和青年项目各1项,深圳市基础研究项目2项。2020年获得广东省自然科学“杰出青年”基金。

  1. Qin Yin*; Yong-Jie Shi; Jingxin Wang; Xumu Zhang*, Direct Catalytic Asymmetric Synthesis of α-Chiral Primary Amines, Chem. Soc. Rev., 2020, ‏49, 6141-6153. (IF 42.846, 2020-07-15)
  2. Yao Zhang, Yun-Qi Liu, Le’an Hu, Xumu Zhang,* and Qin Yin*, Asymmetric Reductive Amination/Ring-Closing Cascade: Direct Synthesis of Enantioenriched Biaryl-Bridged NH Lactams, Org. Lett. 2020, 22, 6479–6483. (IF 6.091)
  3. Yongjie Shi, Xuefeng Tan, Shuang Gao, Yao Zhang, Jingxin Wang, Xumu Zhang, and Qin Yin*, Direct Synthesis of Chiral NH Lactams via Ru-Catalyzed Asymmetric ReductiveAmination/Cyclization Cascade of Keto Acids/Esters, Org. Lett. 2020, 22, 2707−2713. (IF 6.091, 2020-03-19)
  4.  Le’ an Hu, Yao Zhang, Qing-Wen Zhang, Qin Yin,* and Xumu Zhang, Ruthenium-Catalyzed Direct Asymmetric Reductive Amination of Diaryl and Sterically Hindered Ketones with Ammonium Salts and H2, Angew. Chem. Int. Ed. 2020, 59, 5321-5325. (IF 12.959, 2020-01-17) (Highlighted by Chin. J. Org. Chem. 2020, 40, 1802)
  5. Le’an Hu, Yao Zhang, Gen-Qiang Chen, Bi-Jin Lin, Qing-Wen Zhang,* Qin Yin,*and Xumu Zhang*, CuH-Catalyzed Atropoenantioselective Reduction of Bringmann’s Lactones via Dynamic Kinetic Resolution, Org. Lett. 2019, 21, 5575-5580. (IF 6.091, 2019-06-27)
  6. Tao Yang, Xiaochong Guo, Qin Yin* and Xumu Zhang*, Intramolecular Asymmetric Reductive Amination: Synthesis of Enantioenriched Dibenz[c,e]azepines, Chem. Sci. 2019, 10, 2473-2477. (IF 9.346, 2018-12-27)
  7.  Yazhou Lou, Yutao Hu, Jiaxiang Lu, Fanfu Guan, Gelin Gong, Qin Yin*, Xumu Zhang*, Dynamic Kinetic Asymmetric Reductive Amination: Synthesis of Chiral Primary β-amino Lactams, Angew. Chem. Int. Ed. 2018, 57, 14193-14197. (IF 12.959, 2018-09-07)
  8.  Gen-Qiang Chen, Bi-Jin Lin, Jia-Ming Huang, Ling-Yu Zhao, Qi-Shu Chen, Shi-Peng Jia, Qin Yin* and Xumu Zhang*; Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2. J. Am. Chem. Soc. 2018, 140, 8064–8068. (IF 14.612, 2018-06-19) (Highlighted by Synfacts 2018, 14, 1050.)
  9.  Qiwei Lang, Guoxian Gu, Yaoti Cheng, Qin Yin* and Xumu Zhang*; Highly Enantioselective Synthesis of Chiral γ-Lactams by Rh-Catalyzed Asymmetric Hydrogenation. ACS Catal. 2018, 8, 4824−4828. (IF 12.35, 2018-04-23 ) (Highlighted by Synfacts 2018, 14, 0832.)
  10.  Xuefeng Tan, Shuang Gao, Weijun Zeng, Shan Xin, Qin Yin* and Xumu Zhang*; Asymmetric Synthesis of Chiral Primary Amines by Ruthenium-Catalyzed Direct Reductive Amination of Alkyl Aryl Ketones with Ammonium Salts and Molecular H2. J. Am. Chem. Soc. 2018, 140, 2024–2027. (IF 14.612, 2018-01-29) (Highlighted by Synfacts 2018, 14, 0504. and Org. Process Res. Dev. 2018, 22, 421−429.) ESI高被引论文
  11.  Guoxian Gu, Jiaxiang Lu, Ouran Yu, Jialin Wen,* Qin Yin* and Xumu Zhang*; Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of α‑Substituted β‑Ketoesters via Dynamic Kinetic Resolution. Org. Lett. 2018, 20, 1888−1892. (IF 6.091, 2018-04-06)
  12.  Qin Yin, Hendrik F. T. Klare*, and Martin Oestreich*; Catalytic Friedel–Crafts C–H Borylation of Electron-Rich Arenes: Dramatic Rate Acceleration by Added Alkenes. Angew. Chem. Int. Ed. 2017, 56, 3712–3717. Highlighted in SYNFACTS 2017, 13, 529. and Org. Process Res. Dev. 2017, 21, 675–688. (IF 12.959, 2017-02-28)
  13. Qin Yin* and M. Oestreich*; Photocatalysis Enabling Acceptorless Dehydrogenation of Benzofused Saturated Rings at Room Temperature, Angew. Chem. Int. Ed. 2017, 56, 7716–7718. (IF 12.959, 2017-05-02)
  14. Qin Yin, Hendrik F. T. Klare, and Martin Oestreich*; Friedel‒Crafts-type Intermolecular C–H Silylation of Electron-Rich Arenes Initiated by Base Metal Salts. Angew. Chem. Int. Ed. 2016, 55, 3204–3207. (IF 12.959, 2016-01-28)
  15. Qin Yin, Shou-Guo Wang, Xiao-Wei Liang, De-Wei Gao, Jun Zheng and Shu-Li You*; Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179–4183. (IF 9.346, 2015-04-27)
  16.  Qin Yin and Shu-Li You*; Chiral Phosphoric Acid-Catalysed Friedel–Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones. Chem. Sci. 2011, 2, 1344–1348. (IF 9.346, 2011-05-10)
  17. Qin Yin, Yashar Soltani, Rebecca Melen,* and Martin Oestreich*; BArF3-Catalyzed Imine Hydroboration with Pinacolborane Not Requiring the Assistance of an Additional Lewis Base. Organometallics 2017, 36, 2381–2384. (Top 2 most accessed paper in July, 2017.) (IF 4.051, 2017-06-19)
  18. Qin Yin, Sebastian Kemper, Hendrik F. T. Klare, and Martin Oestreich*, Boron Lewis Acid-Catalyzed Hydroboration of Alkenes with Pinacolborane: BArF3 Does What B(C6F5)3 Cannot Do! Chem. Eur. J. 2016, 22, 13840–13844. (IF 4.857, 2016-07-22)
  19. Qin Yin and Shu-Li You*; Asymmetric Chlorocyclization of Indole-3-yl-benzamides for the Construction of Fused-indolines. Org. Lett. 2014, 16, 2426–2429. (IF 6.091, 2014-04-14)
  20.  Qin Yin and Shu-Li You*; Asymmetric Chlorination/Ring Expansion for the Synthesis of α-Quaternary Cycloalkanones. Org. Lett. 2014, 16, 1810–1813. (IF 6.091, 2014-03-11)
  21. Qin Yin and Shu-Li You*; Enantioselective Chlorocyclization of Indole Derived Benzamides for the Synthesis of Spiro-indolines. Org. Lett. 2013, 15, 4266–4269. (IF 6.091, 2013-08-02)
  22. Qin Yin, Shou-Guo Wang and Shu-Li You*; Asymmetric Synthesis of Tetrahydro-β-carbolines via Chiral Phosphoric Acid Catalyzed Transfer Hydrogenation Reaction. Org. Lett. 2013, 15, 2688-2691. (IF 6.091, 2013-06-07)
  23. Qin Yin and Shu-Li You*; Intramolecular Alkene Electrophilic Bromination Initiated ipso-Bromocyclization for the Synthesis of Functionalized Azaspirocyclohexadienones. Org. Lett. 2012, 14, 3526–3529. (IF 6.091, 2012-07-06)

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