Bo Xiao

Professor Department of Biology

An immunologist turned neurobiologist, Dr. Xiao was trained in immunology first at Beijing Medical University and then at the University of Toronto, Canada. He joined the Johns Hopkins University School of Medicine, Baltimore, to study neuroscience, first as postdoctoral fellow and then as a research faculty. Dr. Xiao is among the 20 most cited Chinese neuroscientists (2014-2018) in mainland China.

Personal Profile


◆ Functional Interactions Among Neurons and Neuroglia in Health and Disease;

◆ Molecular Regulation of Oligodendrocyte and Myelin development;

◆ Microglia Function in Neuro-Degeneration/Regeneration;

◆ Neuro-Metabolism, Oxidative Stress, and Neuro-Degeneration.

Publications Read More

1.Tan H, Chen M, Xia X, Pang D, Du C, Yang W, Cui Y, Huang C, Jiang W, Li C, Shang H, Worley PF, Xiao B#. LanCL1 Promotes Motor Neuron Survival and Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice. Cell Death and Differentiation, 2019 Sep 30. doi: 10.1038/s41418-019-0422-6

2.Zou Y, Jiang W, Zhang J, Bu J, Wang J, Zou J, Zhou L, Yu S, Yang W, Luo L, Lu QR, Liu Y, Chen M, Worley PF, Xiao B#. Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain. Journal of Neuroscience. 2014, 34(47):15764-15778

3.Huang C, Chen M, Pang D, Bi D, Zou Y, Xia X, Yang W, Luo L, Deng R, Tan H, Zhou L,Yu S, Guo L, Du X, Cui Y, Hu J, Mao Q, Worley PF, Xiao B#. Developmental and activity-dependent expression of LanCL1 confers antioxidant activity required for neuronal survival. Developmental Cell. 2014;30(4): 479-487 (Featured Article)

4.Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PU, Worley PF, Bo Xiao#. Rheb1 is Required for mTORC1 and Myelination in Postnatal Brain Development. Developmental Cell. 2011;20(1):97-108

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