研究助理教授 医学院

王琢,南方科技大学医学院研究助理教授,于2014年从香港理工大学获得细胞生物学博士学位,之后于南方科技大学完成两年的博士后研究工作。

个人简介

研究领域

主要研究领域为包括肝脏疾病的发病机制的研究以及新型分子靶向治疗策略的开发。


学术成果 查看更多

1. Zhuo Wang#*, Ming Yan#, Jia’an Li, Jiafu Long, Hongmin Zhang*. Dual functions of STAT in LPS-induced angiogenesis of hepatocellular carcinoma. Biochimica et Biophysica Acta-molecular cell research. 2019 Apr;1866(4):566-574

2. Zhuo Wang*, Jia’an Li, Wen’ang Xiao, Jiafu Long, Hongmin Zhang*. STAT3 inhibitor S3I-201 suppresses the fibrogenesis and angiogenesis in liver fibrosis. Laboratory Investigation. 2018; 96(12): 1600-12

3. Lei H, Yan J, Yu J, Liu Y, Wang Z, Xu Z, Ye T. Total Synthesis and Stereochemical Reassignment of Mandelalide A. Angewandte Chemie International Edition. 2014, 53, 6533-6537

4. Wang X, Lv C, Liu J, Tang L, Feng J, Tang S, Wang Z, Liu Y, Meng Y, Ye T, Xu Z. Total Synthesis of the Proposed Structure for Itralamide B. Synlett, 2014, 25, 1014

5. Wang Z, Liu Y, Wang J, Lam W, Kwong S, Li F, Friedman SL, Zhou S, Ren Q, Xu Z, Wang X, Ji L, Tang S, Zhang H, Lui EL, Ye T. A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling. Liver Int. 2013; 33(4): 504-15

6. Long B, Tang S, Chen L, Qu S, Chen B, Liu J, Maguire AR, Wang Z, Liu Y, Zhang H, Xu Z, Ye T.. Total Synthesis of Padanamides A and B. Chem. Commun. 2013, 49, 2977-9

7. Liu H, Liu Y, Wang Z, Xing X, Maguire AR, Luesch H, Zhang H, Xu Z, Ye T. Total Synthesis and Biological Evaluation of Grassypeptolide A. Chemistry-A European Journal, 2013, 19. 6774-84

8. Dai L, Liu Y, Liu J, Wen X, Xu Z, Wang Z, Sun H, Tang S, Maguire AR, Quan J, Zhang H, Ye T. A Novel CyclinE/CyclinA-CDK2 Inhibitor Targets p27Kip1 Degradation, Cell Cycle Progression and Cell Survival: Implications in Cancer Therapy. Cancer Letters, 2013, 333, 103-12

9. Liu J, Ma X, Liu Y, Wang Z, Kwong S, Ren Q, Tang S, Meng Y, Xu Z, Ye T. Total Synthesis and Stereochemical Revision of Burkholdac A. Synlett, 2012, 19, 783-787

10. Dai L, Chen B, Lei H, Wang Z, Liu Y, Xu Z, Ye T. Total Synthesis and Stereochemical Revision of Lagunamide A. Chem. Commun. 2012, 48, 8697-8699.

11. Liu Y, Wang Z, Kwong SQ, Lui EL, Friedman SL, Li FR, Lam RW, Zhang GC, Zhang H, Ye T. Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. J Hepatol. 2011; 55(3):612-25

12. Jin Y, Liu Y, Wang Z, Kwong S, Xu Z, Ye T. Total synthesis of sintokamide C. Org Lett. 2010;12(5):1100-3

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南方科技大学医学院 的定位是建设一所扎根深圳,面向中国和世界、理工医人文交叉融合、水平一流、国际化的研究型医学院。以培养具有国际视野、开拓精神和创新能力、德才兼备的医学领军人才,探索医学未知、引领一流科研、推进医学发展,和追逐精湛医技/医疗、提供优质临床服务为最高使命

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广东省深圳市南山区学苑大道1088号南方科技大学第二科研楼B栋

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电子邮箱

wangz3@sustech.edu.cn

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