Associate Professor Core Research Facilities

Yu Chung Tse, Ph.D., Associate Professor.He got his Ph.D. at 2007 in The Chinese University of Hong Kong, and then he worked as Postdoctoral fellow in The University of Chicago for 5 years. Dr. Tse is fully experienced in the research of cell biology, and he is mainly interested on cell division, cell polarity, cell adhesion and developmental biology. His researches are supporting by National Natural Science Foundation of China (NSFC) and Shenzhen Science, Technology and Innovation Commission (SZSTI).

Personal Profile


My lab is mainly interested in cell biology researches. We particularly interested in study cytokinesis, cell adhesion, cell migration and related developmental process. Currently, we use nematode C. elegans and cultured human cells as the model systems and combine with live cell imaging, genetics and biochemistry to address the following problem:

(1) What is the molecular mechanism of cytokinesis?

(2) How does extracellular matrix regulate cytokinesis?

(3) What is the molecular mechanism of cell adhesion and its related developmental process?

(4) What is the molecular mechanism of cell migration?

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1. Li L, Wang S, Lan H, Gong G, Zhu Y, Tse YC#, Wong KM#. Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid. ChemistryOpen 7: 136-143.

2. Li L, Wang C, Wu J, Tse YC#, Cai YP, Wong KM#. (2016) A Molecular Chameleon with Fluorescein and Rhodamine Spectroscopic Behaviors. Inorganic Chemistry 55: 205-213.

3. Basant A, Lekomtsev S, Tse YC, Zhang D, Longhini KM, Petronczki M, Glotzer M. (2015) Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Developmental Cell 33: 204-215

4. Tse YC*, Werner ME, Longhini MK, Labbe JC, Goldstein B, Glotzer M. (2012) RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Molecular Biology of the Cell 23: 4023-4031.

5. Tse YC*, Wang J, Jiang L. (2012) Multivesicular bodies in developing tobacco seed and mung bean are functionally equivalent. Plant Signaling & Behavior 7:1-4.

6. Tse YC*, Piekny A, Glotzer M. (2011) Anillin promotes astral microtubule-directed cortical myosin polarization. Molecular Biology of the Cell 22:3165-3175.

7. Wang J, Tse YC, Hinz G, Robinson DG, Jiang L. (2011) Storage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean. Journal of Experimental Botany 63:1367-1380.

8. Afshar K, Werner ME^, Tse YC^, Glotzer M, Gönczy P. (2010) Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos. Development 137:237-47. (^ these authors contributed equally to this work.)

9. Wang H, Tse YC, Law AH, Sun SS, Sun YB, Xu ZF, Hillmer S, Robinson DG, Jiang L. (2010) Vacuolar sorting receptors (VSRs) and secretory carrier membrane proteins (SCAMPs) are essential for pollen tube growth. The Plant Journal 61:826-838.

10. Tse YC*, Lam SK, Jiang L. (2009) Organelle identification and characterization in plant cells: Using a combinational approach of confocal immunofluorescence and electron microscope. Journal of Plant Biology 52:1-9.

11. Lam SK, Cai Y, Tse YC, Wang J, Law AH, Pimpl P, Chan HY, Xia J, Jiang L. (2009) BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells. The Plant Journal 60:865-881.

12. Lam SK, Tse YC, Miao Y, Li HY, Wang J, Lo SW, Jiang L. (2007) Molecular characterization of plant prevacuolar and endosomal compartments. Journal of Integrative Plant Biology 49:1119-1128.

13. Lam SK, Tse YC, Robinson DG and Jiang L. (2007) Tracking down the elusive early endosome. Trends in Plant Science 12: 497-505.

14. Tse YC*, Lam SK and Jiang L. (2007) Enigmatic Brefeldin A. Plant Signaling & Behavior. Plant Physiology 2: 199-202.

15. Tse YC*, Lo SW, Hillmer S, Dupree P and Jiang L. (2006) Dynamic response of prevacuolar compartments to Brefeldin A in plant cells. Plant Physiology 142:1442-1459.

16. Oliviusson P, Heinzerling L, Hillmer S, Hinz G, Tse YC, Jiang L and Robinson DG. (2006) Plant retromer: identification, localization to the prevacuolar compartment and microvesicles, and preliminary evidence for an interaction with vacuolar sorting receptors. Plant Cell 18:1239-1252.

17. Tse YC*, Mo BX* and Jiang L. (2006) Plant prevacuolar/endosomal compartments. International Review of Cytology 253:95-129. (* these authors contributed equally to this work.)

18. Fung KL, Yim YF, Tse YC, Miao Y, Sun SSM and Jiang L. (2005) Targeting and processing of membrane-anchored YFP fusion proteins to protein storage vacuole in transgenic tobacco seeds. Seed Science Research 15:361-364.

19. Lam SK, Tse YC, Jiang L, Oliviusson P, Heinzerling L and Robinson DG. (2005) Plant prevacuolar compartments and endocytosis. In “Plant Endocytosis” Samaj, J., Baluska, F. and Menzel, D. (eds) Plant Cell Monographs 1:37-61.

20. Tse YC*, Mo B, Zhao M, Robinson DG, Hillmer S, Lo SW and Jiang L. (2004) Identification of multivescular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. Plant Cell 16:672-693.

21. Jin JB, Bae H, Kim SJ, Jin YH, Goh CH, Kim DH, Lee YJ, Tse YC, Jiang L and Hwang I. (2003) The Arabidopsis dynamin-like proteins ADL1C and ADU1E play a critical role in mitochondrial morphogenesis. Plant Cell 15:2357-2369.

22. Mo B, Tse YC and Jiang L. (2003) Organelle identification and proteomics in plant cells. Trends in Biotechnology 21:331-332.

23. Li YB, Rogers SW, Tse YC, Lo SW, Sun SSM., Jauh GY and Jiang L. (2002) BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant & Cell Physiology 43:726-742.

24. Lee SM, Li ML, Tse YC, Leung SC, Lee MM, Tsui SK, Fung KP, Lee CY, Waye MM. (2002) Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. Life Science. 71:2267-2277.

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Welcome to the Department of Biology! Since its establishment in 2012, the Department of Biology has attracted internationally renowned professors to join as leaders and dozens of young scientists to start their independent academic career here pursuit of excellence in research and teaching. The research interests of our faculty members include diverse topics such as systems biology, plant biology, neurobiology, structural biology and molecular cell biology. The primary goals of our faculty are to address the most significant fundamental biological questions and to develop new strategies to treat various complex diseases. Such efforts will benefit from the shared inter-disciplinary collaborative spirit deeply rooted in the minds of all the faculty members working in different departments at SUSTech.


Mentoring the next generation biologists with the highest standards is another primary task of the Department of Biology. Our professors choose internationally acclaimed textbooks to teach core courses biological sciences, biotechnology and bioinformatics. Undergraduates are encouraged to join the laboratory early to get firsthand working experience in basic and/or applied biological research, which helps them to consolidate the mastering of basic techniques, to broaden their knowledge horizons and to acquire the capabilities of problem identifying, hypothesis formulating and problem solving.


Life science, one of the fastest developing natural scientific disciplines, has been the driving force behind the growth of the world economy and provides the know for the development of new technologies serving to improve the human health and welfare at large. Wit generous financial support from the Shenzhen municipal government, we are confident that the Department of Biology in SUSTech will surely grow into a top tier globally-renowned research and teaching center!


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