associate professor Department of Biology

Dr. Song Kun obtained both bachelor’s and master’s degrees at Nankai University. Then, he pursued his Ph.D. degree in Biology at Max-Delbruck Center for Molecular Medicine / Free University Berlin, Germany. From 2014 to 2019, he received consecutive postdoctoral training in Prof. Wei Chen’s group and Prof. Carmen Birchmeier’s group at the biomedical institute – Max-Delbruck Center. Dr. Song came back to China in 2019 and became an associate professor at the Southern University of Science and Technology (SUSTech). He mainly focuses on interrogating the mechanisms of different physiological functions orchestrated by the nervous system using mouse models and interdisciplinary approaches.


Human and other mammalian species maintain a variety of the functional homeostasis via the feedback regulation orchestrated by the nervous system. Our group takes core body temperature regulatory function as a representative model to interrogate the mechanisms of different homeostatic functions using a battery of multiple modern biological technologies and transgenic mouse models.

Personal Profile


(1)The molecular mechanisms and neural circuitry of thermosensation and thermoregulation - a model to investigate the mechanisms of homeostatic functions orchestrated by the nervous system;

(2)Exploring the developmental atlas and the underlying mechanisms of nervous system using techniques of single-cell omics;


《Modern biotechnology》

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(*co-first author; #co-corresponding author)

[1] Fendler A, Bauer D, Busch J, Jung K, Wulf-Goldenberg A, Kunz S, Song K, Myszczyszyn A, Elezkurtaj S, Erguen B, Jung S, Chen W, Birchmeier W. Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients. Nat Commun (2020) 11:929.

[2] Rathjen T*, Yan X*, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JF, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN. Regulation of body weight and energy homeostasis by neuronal Cell adhesion molecule 1. Nat Neurosci. 2017, 20(8):1096-1103.

[3] Song K*, Wang H*, Kamm GB*, Pohle J, de Castro Reis F, Heppenstall P, Wende H, Siemens J. The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia. Science. 2016, 353(6306):1393-8.

[4] Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, Loewer A, Utikal J, Lewin GR, Lechner SG, Siemens J. PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors. Nat Neurosci. 2015, 18(1):10-6.

[5] Pan L, Song K#, Hu F, Sun W, Lee I#. Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca2+ entry via S-nitrosylation in osteoblasts. Eur J Pharmacol. 2013, 715(1-3):280-5.

[6] Pan L, Zhang X, Song K, Tang B, Cai W, Wu X, Rupp RA, Xu J. Real-time imaging of autofluorescence NAD(P)H in single human neutrophils. Applied Optics. 2009, 48(6): 1042-1046.

[7] Pan L, Zhang X, Song K, Wu X, Xu J. Exogenous nitric oxide-induced release of calcium from intracellular IP3 stores via S-nitrosylation in respiratory burst-dependent neutrophils. Biochem Biophys Res Commun. 2008, 377(4):1320-5.

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Welcome to the Department of Biology! Since its establishment in 2012, the Department of Biology has attracted internationally renowned professors to join as leaders and dozens of young scientists to start their independent academic career here pursuit of excellence in research and teaching. The research interests of our faculty members include diverse topics such as systems biology, plant biology, neurobiology, structural biology and molecular cell biology. The primary goals of our faculty are to address the most significant fundamental biological questions and to develop new strategies to treat various complex diseases. Such efforts will benefit from the shared inter-disciplinary collaborative spirit deeply rooted in the minds of all the faculty members working in different departments at SUSTech.


Mentoring the next generation biologists with the highest standards is another primary task of the Department of Biology. Our professors choose internationally acclaimed textbooks to teach core courses biological sciences, biotechnology and bioinformatics. Undergraduates are encouraged to join the laboratory early to get firsthand working experience in basic and/or applied biological research, which helps them to consolidate the mastering of basic techniques, to broaden their knowledge horizons and to acquire the capabilities of problem identifying, hypothesis formulating and problem solving.


Life science, one of the fastest developing natural scientific disciplines, has been the driving force behind the growth of the world economy and provides the know for the development of new technologies serving to improve the human health and welfare at large. Wit generous financial support from the Shenzhen municipal government, we are confident that the Department of Biology in SUSTech will surely grow into a top tier globally-renowned research and teaching center!


Undergraduate Major:
Biological Sciences


Master & PhD degree program:

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