Principal Investigator Department of Chemistry, Grubbs Institute

Dr. Wei SHU is a Principal Investigator in the department of chemistry and a joint professor of Shenzhen Grubbs Institute at Southern University of Science and Technology (SUSTech). Dr. Wei SHU received his bachelor degrees at Nankai University in chemistry and economics in 2005. He continued his graduate studies at Shanghai Institute of Organic Chemistry (SIOC, CAS), and obtained his Ph. D. degree in 2010 under the guidance of Profs. Shengming Ma and Guochen Jia. After several postdoctoral stints at Massachusetts Institute of Technology (Stephen L. Buchwald), Princeton University (David W. C. Macmillan), and University of Zurich (Cristina Nevado), he started his independent research at Southern University of Science and Technology (SUSTech) in 2018 as an associate professor. His research interests span over methodology development, asymmetric synthesis, medicinal chemistry, flow chemistry and material sciences, with an emphasis on first-row transition metal catalysis, photochemistry, and single electron catalysis. Dr. Shu is the recipient of "1000" Talents Recruitment Program for Young Scholars, The Pearl River Talent Recruitment Program, and the Thieme Chemistry Journals Award in 2021.

Personal Profile


1. First-row transition-metal catalyzed C-C and C-X bond forming reactions

2. Asymmetric catalysis

3. Merging catalysis of visible light and transition metals

4. Microflow chemistry

5. Medicinal chemistry

6. Organic material sciences


Organic Chemistry I (CH203,Basic course for chemistry)

Organic Chemistry II (CH206,Basic course for chemistry)

Publications Read More

Most recent publications:

1. Shan Wang, Jian-Xin Zhang, Tian-Yi Zhang, Huan Meng, Bi-Hong Chen, and Wei Shu*Enantioselective Access to Chiral Aliphatic Amines and Alcohols via Ni-Catalyzed Hydroalkylations.

Nature Commun. 2021, 12, 2771.

2. Yi-Dan Du, Bi-Hong Chen, and Wei Shu*Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination.

Angew. Chem. Int. Ed. 2021, 60, 9875-9880 (Hot Paper).

3. Yi-Zhou Zhan, Nan Xiao, and Wei Shu*, Ni-Catalyzed Regio- and Stereodefined Intermolecular Cross-Electrophile Dialkylation of Alkynes Without Directing Group.

Nature Commun. 2021, 12, 928.

4. Lou Shi, Ling-Ling Xing, Wen-Bo Hu, and Wei Shu*Regio- and Enantioselective Ni-Catalyzed Formal Hydroalkylation, Hydrobenzylation and Hydropropargylation of Acrylamides to α-Tertiary Amides.

Angew. Chem. Int. Ed. 202160, 1599-1604.

5. Ming-Shang Liu, Lin Min, Bi-Hong Chen, and Wei Shu*, Dual Catalysis Relay: Coupling of Aldehydes and Alkenes Enabled by Visible-Light and NHC-Catalyzed Cross-Double C-H Functionalizations.

ACS Catalysis, 2021, 11, 9715-9721.

6. Nan Xiao,§ Yi-Zhou Zhan,§ Huan Meng,§ and Wei Shu*, Access to Z-Selective Enynes via Ni-Catalyzed Intermolecular Cross-Alkylalkynylation of Terminal Alkynes.

Org. Lett. 2021DOI: 10.1021/acs.orglett.1c01728, online. (§ equal contribution).

7. Sifan Li, Yu Wang, Zibo Wu, Weiliang Shi, Yibo Lei, Paul W. Davies,* and Wei Shu*, A Radical-Initiated Fragmentary Rearrangement Cascade of Ene-Ynamides to [1,2]-Annulated Indoles via Site-Selective Cyclization.

Organic Letters 2021, DOI: 10.1021/acs.orglett.1c02519.

8. Yu Wang, Jian-Xin Zhang, and Wei Shu*Cu-Catalyzed Remote Transarylation of Amines via Unstrained C-C Functionalization.

ACS Catal. 20201015065-15070.

9. Ming-Shang Liu and Wei Shu*Catalytic, Metal-Free Amide Synthesis from Aldehydes and Imines Enabled by a Dual-Catalyzed Umpolung Strategy under Redox-Neutral Conditions.

ACS Catal. 202010, 12960-12966.

10. Peng-Fei Yang and Wei Shu*Direct Synthesis of Mono-α-Arylated Ketones from Alcohols and Olefins via Ni-Catalyzed Oxidative Cross-Coupling.

Org. Lett. 2020, 22, 6203-6208.

11. Wei Shu, Andrés GarcíaDomínguez, M. Teresa Quirós, Rahul Mondal, Diego J. Cárdenas, and Cristina Nevado*, Ni‑Catalyzed Reductive Dicarbofunctionalization of  Nonactivated Alkenes: Scope and Mechanistic Insights.

J. Am. Chem. Soc. 2019, 141, 13812-13821.

12. Xu-Lu Lv and Wei Shu*Unified and Practical Access to ɤ-Alkynylated Carbonyl Derivatives via Streamlined Assembly at Room Temperature.

Commun. Chem. 2019, 2, 119.

13. Wei Shu*, Hui Zhang and Yan Huang, γ-Alkylation of Alcohols Enabled by Visible-Light Induced 1,6-Hydrogen Atom Transfer.

Org. Lett. 201921, 6107-6111.

14. Xu-Lu Lv, Cong Wang, Qiao-Li Wang, and Wei Shu*, Rapid Synthesis of γ‑Arylated Carbonyls Enabled by the Merge of Copper- and Photocatalytic Radical Relay Alkylarylation of Alkenes.

Org. Lett. 201921, 56-59.

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  • SUSTech Wei Shu’s group achieves significant progress in first-row transition-metal catalysis


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Department of Chemistry, Southern University of Science and Technology, Shenzhen, P. R. China 518055

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