Associate professor |School of Life Sciences, Department of Biology

Dr. LIU has focused on teleost biology research that includes developmental and molecular genetics (zebrafish and medaka), molecular endocrinology (salmons) studies, and transgenesis (cyprinid fish) and genome editing (zebrafish) techniques. Starting from my postdoctoral training, we have used zebrafish to study how mechanosensory hair cells develop and regenerate upon damage; and to model human diseases for drug screening purpose. We have also used C. elegans to develop and test new ways to study functions of non-coding RNAs and a relationship between germ cells and somatic sex development.

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Our team has been engaged in the comparison of the development / regeneration mechanism of the peripheral nervous system of zebrafish for a long time. In recent years, we have also carried out the modeling work of human diseases. By means of cytology, molecular genetics, neurobiology and behavioral science, we have established a variety of zebrafish models related to the imbalance of inner ear and the development disorder of central nervous system Disease and treatment mechanism.


《Model biology and developmental biology》

《Principles of animal morphogenesis》

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1. Li J, Liu, Y-q, Li Q, H X-l,  Zhou D-x, Xu H-j, Zhao F,  Mi X-x,  Wang R-x, Jia F, Xu F-q, Yang J, Liu Dong; Deng X-l, Zhang Y,  Huang X,  Zhang Y .(2021). Mutation in ε-sarcoglycan induces a myoclonus-dystonia syndrome-like movement disorder in mice. 神经科学通报:英文版, 37(3), 12.

2.Lu Jeng-Wei; Sun, Yuxi; Lin, Liang-In; Liu, Dong; Gong, Zhiyuan. Exacerbation of Liver Tumor Metastasis in twist1a+/xmrk+ Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure[J]. Pharmaceuticals, 2021, 14.

3.Lu, Jeng-Wei; Sun, Yuxi; Fong, Pei Shi Angelina; Lin, Liang In; Liu, Dong; Gong, Zhiyuan. Lipopolysaccharides Enhance Epithelial Hyperplasia and Tubular Adenoma in Intestine-Specific Expression of krasV12 in Transgenic Zebrafish[J]. Biomedicines, 2021, 9(8):974.

4.Zhang, Mengtao; Zhao, Feng; Zhang, Jiawei; Shi, Jianghong; Tao, Huanyu; Ge, Hui; Guo, Wei; Liu, Dong; Cai, Zongwei. Toxicity and accumulation of 6-OH-BDE-47 and newly synthesized 6,6′-diOH-BDE-47 in early life-stages of Zebrafish ( Danio rerio )[J]. Science of The Total Environment, 2020.

5.Sun P, Zhang Y, Zhao F, Wu J-P, Pun SH, Peng C, Du M, Vai MI, Liu D*, Chen F*. (2018). An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae. Front Cell Neurosci, doi:10.3389/fncel.2018.00257

6.Zhang J, Zhang T, Yu L, Ruan Q, Yin L, Liu D, Zhang H, Bai P, Ren Z. (2018). Effects of ovarian reserve and hormone therapy on hearing in premenopausal and postmenopausal women: A cross-sectional study. Maturitas, 111: 77-81

7.Li X, Song G, Zhao Y, Zhao F, Liu C, Liu D*, Li Q*, Cui Z*. (2018). Claudin7b is required for the formation and function of inner ear in zebrafish. J Cell Physiol, 233(4): 3195-3206. doi: 10.1002/jcp.26162

8.Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y., Zhang K, Schumann G, Liu D*, Wang J*, Wang Y*, Lu L. (2018). A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder. Mol Psychiatry, 23:1014-1020. doi:10.1038/mp.2017.74

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