生物系

刘闯博士师从北京大学尹长城教授学习冷冻电子显微学,后又在美国匹兹堡大学章佩君教授实验室从事冷冻电镜博士后研究工作。目前研究的主要工作是基于冷冻电镜的新技术开发及生命体中重要蛋白、细胞器的结构解析。

个人简介

研究领域

1 心肌/骨骼肌细胞中的肌肉收缩偶联的结构研究

2 急/慢性心脏疾病心肌细胞线粒体的原位结构研究

3 生物大分子螺旋复合物的结构解析


学术成果 查看更多

1. Liu C., Fan G., Wang Z., Chen H., Yin C.,(2017) Allosteric conformational changes of human HBV core protein transform its assembly., Scientific Reports, DOI: 10.1038/s41598-017-01568-9.

2. Liu C., Perilla J., Ning J., Lu M., Hou G., Ramalho R., Himes B., Zhao G., Bedwell G., Byeon I., Ahn J., Gronenborn A., Prevelige P., Rousso I, Polenova T., Schulten K., Zhang P. (2016) Cyclophilin A Stabilizes HIV-1 Capsid through a Novel Non-canonical Binding Site. Nature Communications: 7:10714, DOI:10.1038

3. Tillman T.S., Alvarez F.J., Reinert N.J., Liu C., Wang D., Xu Y., Xiao K., Zhang P. and Tang P. (2016) Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from E. coli. J Biol Chem. Pii: jbc.M116.729970.

4. Lu J, Liu C, Wang P, Ghazwani M, Xu J, Ma X, Zhang P, Li S., (2015) The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin.Biomaterials. Sep: 62:176-87

5. Zhang K. Ezemaduka A., Wang Z.,Hu H., Shi X., Liu C., Lu X., Fu X., Chang Z.& Yin C.,(2015),A Novel Mechanism for Small Heat Shock Proteins to Function as Molecular Chaperones; Scientific Reports:8811

6. Saini S.G., Liu C., Zhang P. and Lee T.H. (2014). Membrane Tethering by the Atlastin GTPase Depends on GTP Hydrolysis But Not on Forming the crossover Configuration.Mol Biol Cell 25(24):3942-53

团队成员 查看更多

加入团队

联系我们

联系地址

办公电话

电子邮箱

Copyright © 2018 All Rights Reserved.