副教授 生物系

2016年博士毕业于香港浸会大学,2016-2020年在香港浸会大学做博士后及研究助理教授,2020年起受聘于南方科技大学生物系副教授。长期致力于骨关节相关疾病以及肿瘤的机制研究、转化医学和精准医学。

个人简介

研究领域

骨关节相关疾病以及肿瘤的机制研究、转化医学和精准医学。


学术成果 查看更多

1.Liang C*, Guo B, Wu H, Shao N, Li D, Liu J, Dang L, Wang C, Li H, Li S, Lau WK, Cao Y, Yang Z, Lu C, He X, Au DW, Pan X, Zhang BT, Lu C, Zhang H, Yue K, Qian A, Shang P, Xu J, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L, Lu A, Zhang G. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nat Med. 2015 Mar;21(3):288-94. doi: 10.1038/nm.3791.

2.Liang C*, Peng S, Li J, Lu J, Guan D, Jiang F, Lu C, Li F, He X, Zhu H, Au DWT, Yang D, Zhang BT, Lu A, Zhang G. Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis. Nat Commun. 2018 Aug 24;9(1):3428. doi: 10.1038/s41467-018-05974-z.

3.Liang C*#, Li J, Lu C, Xie D, Liu J, Zhong C, Wu X, Dai R, Zhang H, Guan D, Guo B, He B, Li F, He X, Zhang W, Zhang BT, Zhang G, Lu A. HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis. Nat Commun. 2019 Oct 8;10(1):4579. doi: 10.1038/s41467-019-12163-z.

4.Liang C*#, Li F, Wang L, Zhang ZK, Wang C, He B, Li J, Chen Z, Shaikh AB, Liu J, Wu X, Peng S, Dang L, Guo B, He X, Au DWT, Lu C, Zhu H, Zhang BT, Lu A, Zhang G. Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma. Biomaterials. 2017 Sep 13;147:68-85. doi: 10.1016/j.biomaterials.2017.09.015.

Li F, Lu J, Liu J, Liang C*, Wang M, Wang L, Li D, Yao H, Zhang Q, Wen J, Zhang ZK, Li J, Lv Q, He X, Guo B, Guan D, Yu Y, Dang L, Wu X, Li Y, Chen G, Jiang F, Sun S, Zhang BT, Lu A, Zhang G. A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer. Nat Commun. 2017 Nov 9;8(1):1390. doi: 10.1038/s41467-017-01565-6.

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联系地址

南方科技大学第一科研楼309室

办公电话

电子邮箱

liangc@sustech.edu.cn

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