Principle Investigator, Associate Professor Department of Biology
Dr. Yuhui Hu has a long-standing interest and experience in functional genomics and Chinese Medicine (CM). She has particular interest in combining her expertise in both systems biology (genomics, metabolomics, proteomics) and CM theories for the research-driven development of new drugs that are originated from CM natural compounds.
As a senior research scientist at Max-Delbrueck-Center for Molecular Medicine, one of the German national biomedical research centers, she has for the first time established a series of high-throughput platforms, such as MecoTCM and Transfected Cell Microarrays, for systematically studying the functional mechanism of CM, and in the meantime allowing for efficient assessment of therapeutic efficacies of CM-derived new drug candidates.
She has identified a few CM-originated compounds with potent anti-cancer and neural protection effects and already collected sound experimental data ready for patenting.
Personal Profile
Dr. Yuhui Hu has a long-standing interest and experience in functional genomics and Chinese Medicine (CM). She has particular interest in combining her expertise in both systems biology (genomics, metabolomics, proteomics) and CM theories for the research-driven development of new drugs that are originated from CM natural compounds.
As a senior research scientist at Max-Delbrueck-Center for Molecular Medicine, one of the German national biomedical research centers, she has for the first time established a series of high-throughput platforms, such as MecoTCM and Transfected Cell Microarrays, for systematically studying the functional mechanism of CM, and in the meantime allowing for efficient assessment of therapeutic efficacies of CM-derived new drug candidates.
She has identified a few CM-originated compounds with potent anti-cancer and neural protection effects and already collected sound experimental data ready for patenting.
The main research & development topics comprise:
- Systems Biology-based research of the function of CM-derived compounds and the underlying molecular mechanisms.
- Pre-clinical study of CM-compounds for new drug development.
- Linking Chemical Biology to Cell biology: Compound-induced metabolic stress & epigenetic changes leading to a new type of DNA damage & repair.
- Cancer genomics & chemical genomics for early diagnosis, therapy, & prognosis.
Research
The main research & development topics comprise:
1) Systems Biology-based research of the function of CM-derived compounds and the underlying molecular mechanisms.
2) Pre-clinical study of CM-compounds for new drug development.
3) Linking Chemical Biology to Cell biology: Compound-induced metabolic stress & epigenetic changes leading to a new type of DNA damage & repair.
4) Cancer genomics & chemical genomics for early diagnosis, therapy, & prognosis.
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She has for the first time established a series of high-throughput platforms, such as MecoTCM and Transfected Cell Microarrays, for systematically studying the functional mechanism of CM, and in the meantime allowing for efficient assessment of therapeutic efficacies of CM-derived new drug candidates.
She has identified a few CM-originated compounds with potent anti-cancer and neural protection effects and already collected sound experimental data ready for patenting.
She has published more than 20 peer-reviewed articles, The total number of citations reached 1200, H-Index at 14(Google Scholar).
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Introduction
Welcome to the Department of Biology! Since its establishment in 2012, the Department of Biology has attracted internationally renowned professors to join as leaders and dozens of young scientists to start their independent academic career here pursuit of excellence in research and teaching. The research interests of our faculty members include diverse topics such as systems biology, plant biology, neurobiology, structural biology and molecular cell biology. The primary goals of our faculty are to address the most significant fundamental biological questions and to develop new strategies to treat various complex diseases. Such efforts will benefit from the shared inter-disciplinary collaborative spirit deeply rooted in the minds of all the faculty members working in different departments at SUSTech.
Mentoring the next generation biologists with the highest standards is another primary task of the Department of Biology. Our professors choose internationally acclaimed textbooks to teach core courses biological sciences, biotechnology and bioinformatics. Undergraduates are encouraged to join the laboratory early to get firsthand working experience in basic and/or applied biological research, which helps them to consolidate the mastering of basic techniques, to broaden their knowledge horizons and to acquire the capabilities of problem identifying, hypothesis formulating and problem solving.
Life science, one of the fastest developing natural scientific disciplines, has been the driving force behind the growth of the world economy and provides the know for the development of new technologies serving to improve the human health and welfare at large. Wit generous financial support from the Shenzhen municipal government, we are confident that the Department of Biology in SUSTech will surely grow into a top tier globally-renowned research and teaching center！
Undergraduate Major:
Biological Sciences
Biotechnology
Bioinformatics
Master & PhD degree program:
Biology
Contact Us
Contact Address
No 1088, xueyuan Rd., Xili, Nanshan District, Shenzhen, Guangdong, China
Office Phone
0755-88018429
huyh(at) sustech.edu.cn [请将(at)更换为@]