Assistant Professor |College of Engineering, Department of Ocean Science and Engineering, |Academy for Advanced Interdisciplinary Studies   Research Group

Dr. Shengwei Hou received his PhD in Bioinformatics at Freiburg University in 2018 under the supervision of Prof. Wolfgang R. Hess in Germany. After that, he collaborated with Prof. Jed A. Fuhrman at the University of Southern California (USC) for his postdoctoral study on marine microbial ecology until July 2021. In August 2021, Dr. Hou started the Computational Microbial Ecology & Evolution (CMEE) lab in the Department of Ocean Science and Engineering at the Southern University of Science and Technology (SUSTech) as an assistant professor. He is interested in biogeography and interactions of marine microbes, host-virus interactions, mechanisms of microbial environmental adaptation and microbial driven biogeochemical cycles, with the objective of understanding microbial responses to global climate change including but not limited to global warming, ocean acidification and hypoxia, etc. Dr. Hou has published more than 20 papers in top-ranking journals including The ISME J, PNAS, Environ Microbial and RNA Biol, etc. Currently, Dr. Hou is a guest editor of Frontiers in Microbiology and a review editor of Frontiers in Marine Science. He is also an experienced reviewer for influential journals including Nature Microbiology, The ISME J, Microbiome, Nature Communications, etc.

Personal Profile

Dr. Shengwei Hou received his Ph.D. in Bioinformatics at Freiburg University in 2018 under the supervision of Prof. Wolfgang R. Hess in Germany. After that, he collaborated with Prof. Jed A. Fuhrman at the University of Southern California (USC) for his postdoctoral study on marine microbial ecology until July 2021. In August 2021, Dr. Hou started the Computational Microbial Ecology & Evolution (CMEE) lab in the Department of Ocean Science and Engineering at the Southern University of Science and Technology (SUSTech) as an assistant professor. He is interested in biogeography and interactions of marine microbes, host-virus interactions, mechanisms of microbial environmental adaptation and microbial driven biogeochemical cycles, with the objective of understanding microbial responses to global climate change including but not limited to global warming, ocean acidification and hypoxia, etc. Dr. Hou has published more than 20 papers in top-ranking journals including The ISME J, PNAS, Environ Microbial and RNA Biol, etc. Currently, Dr. Hou is a guest editor of Frontiers in Microbiology and a review editor of Frontiers in Marine Science. He is also an experienced reviewer for influential journals including Nature Microbiology, The ISME J, Microbiome, Nature Communications, etc.

 

Educational Background

2018 Ph.D., Faculty of Biology, Albert-Ludwig University of Freiburg, Bioinformatics

2013 Master, Institute of Hydrobiology, Chinse Academy of Sciences, Molecular Genetics

2009 Bachelor, Southwest University, Biotechnology

 

Professional Experience

2021 - present Assistant Professor, Department of Ocean Science and Engineering, Southern University of Science and Technology (DOSE, SUSTech)

2018 – 2021 Postdoctoral Scholar – Research Associate, Marine and Environmental Biology, University of Southern California (MEB, USC)

 

Projects

1. Participated in the Simons Collaboration on Computational Biogeochemical Modeling of Marine Ecosystems (CBIOMES) project, funded by Simons Foundation, 2017-2022.

2. Participated in the USC Microbial Observatory at the San Pedro Ocean Time series (SPOT) project, funded by NSF & Moore Foundation, 1998-2022.

3. Participated in the Marine Microorganisms: Cultivation Methods for Improving their Biotechnological Applications (MaCuMBA) project, funded by the European Union, 2012-2016.

 

Selected Publications

1. J. L. Weissman, S. Hou, J. A. Fuhrman. Estimating maximal microbial growth rates from cultures, metagenomes, and single cells via codon usage patterns. Proc Natl Acad Sci. 2021 Mar 23;118(12):e2016810118.

2. A. M. Long#S. Hou#, J. C. Ignacio‑Espinoza, and J. A. Fuhrman. Benchmarking microbial growth rate predictions from metagenomes. The ISME J. 2020: 1‑13.

3. S. Hou#, M. López‑Pérez#, U. Pfreundt, N. Belkin, K. Stüber, B. Huettel, R. Reinhardt, I. Berman‑Frank, F. Rodriguez‑Valera and W. R. Hess. Benefit from decline: The primary transcriptome of Alteromonas macleodii str. Te101 during Trichodesmium demise. The ISME J. 2018 Jan 15:1.

4. S. Hou, M. Brenes, A. M. Muro‑Pastor, W. R. Hess. CRISPR‑Cas systems in multicellular cyanobacteria. RNA Biol. 2018 Aug 15:1‑12.

5. X. Tan#S. Hou#, K. Song, J. Georg, S. Klähn, X. Lu, W. R. Hess. The Primary Transcriptome of the Fast‑Growing Cyanobacterium Synechococcus elongatus UTEX 2973. Biotechnol Biofuels. 2018 Aug 4;11:218.

6. J. E. Teikari#S. Hou#, M. Wahlsten, W. R. Hess and K. Sivonen. Comparative genomics of the Baltic Sea toxic cyanobacteria Nodularia spumigena UHCC 0039 and its response on varying salinity. Front Microbiology 2018 Mar 8;9:356.

7. S. Hou, U. Pfreundt, D. Miller, I. Berman‑Frank, W. R Hess. mdRNA‑Seq analysis of marine microbial communities from the northern Red Sea. Sci Rep. 2016 Oct 19;6:35470.

8. S. Hou, F. Zhou, S. Peng, H. Gao and X. Xu. The HetR‑binding site that activates expression of patA in vegetative cells is required for normal heterocyst patterning in Anabaena sp. PCC 7120. Sci Bull. 2015 Jan;60(2):192‑201.

Research

Computational Biology & Bioinformatics, Microbes and Climate Change, Microbial Ecology and Evolution


Publications Read More

1. J. L. Weissman, S. Hou, J. A. Fuhrman. Estimating maximal microbial growth rates from cultures, metagenomes, and single cells via codon usage patterns. Proc Natl Acad Sci. 2021 Mar 23;118(12):e2016810118.

2. A. M. Long#S. Hou#, J. C. Ignacio‑Espinoza, and J. A. Fuhrman. Benchmarking microbial growth rate predictions from metagenomes. The ISME J. 2020: 1‑13.

3. S. Hou#, M. López‑Pérez#, U. Pfreundt, N. Belkin, K. Stüber, B. Huettel, R. Reinhardt, I. Berman‑Frank, F. Rodriguez‑Valera and W. R. Hess. Benefit from decline: The primary transcriptome of Alteromonas macleodii str. Te101 during Trichodesmium demise. The ISME J. 2018 Jan 15:1.

4. S. Hou, M. Brenes, A. M. Muro‑Pastor, W. R. Hess. CRISPR‑Cas systems in multicellular cyanobacteria. RNA Biol. 2018 Aug 15:1‑12.

5. X. Tan#S. Hou#, K. Song, J. Georg, S. Klähn, X. Lu, W. R. Hess. The Primary Transcriptome of the Fast‑Growing Cyanobacterium Synechococcus elongatus UTEX 2973. Biotechnol Biofuels. 2018 Aug 4;11:218.

6. J. E. Teikari#S. Hou#, M. Wahlsten, W. R. Hess and K. Sivonen. Comparative genomics of the Baltic Sea toxic cyanobacteria Nodularia spumigena UHCC 0039 and its response on varying salinity. Front Microbiology. 2018 Mar 8;9:356.

7. S. Hou, U. Pfreundt, D. Miller, I. Berman‑Frank, W. R Hess. mdRNA‑Seq analysis of marine microbial communities from the northern Red Sea. Sci Rep. 2016 Oct 19;6:35470.

8. S. Hou, F. Zhou, S. Peng, H. Gao and X. Xu. The HetR‑binding site that activates expression of patA in vegetative cells is required for normal heterocyst patterning in Anabaena sp. PCC 7120. Sci Bull. 2015 Jan;60(2):192‑201.

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Lab members Read More

Join us

1. Postdoctoral Researchers in Bioinformatics

    Currently, we are seeking two highly motivated bioinformaticians / computational biologists for well-funded two-year postdoctoral scholar positions focused on:

        (1) bioinformatics software, database, and computational pipeline development,

        (2) marine phytoplankton-heterotroph / host-virus interactions, 

        (3) microbial ecology in coastal hypoxia regions and oxygen minimum zones,

        (4) microbial biogeography, diversity, and adaptative evolution. 

    Applicants are free to choose any or a combination of the above-mentioned research fields. We provide world-leading research equipment and facilities, as well as globally competitive salaries and benefits (including US & HK). To apply, please send your detailed CV, cover letter, and research statement to Dr. Hou (housw@sustech.edu.cn). The start date is flexible, and review of applicants will be ongoing until the positions are filled.  

 

2. Postdoctoral Researcher in Microbiology

    A postdoctoral position in marine microbiology is available immediately. Applicants should have expertise in Microbiology, Molecular Biology, Molecular Virology, or Ecology. The successful applicant will work on phototroph-heterotroph/virus interactions in oxygen-deficient waters using single-cell approaches. To apply, please send your detailed CV, cover letter, and research statement to Dr. Hou (housw@sustech.edu.cn). The start date is flexible and the review process will be ongoing until filled.

 

3. Graduate Students

    Students interested in marine microbiology or bioinformatics are highly encouraged to join our Master's or Ph.D. programs.

 

4. Visiting Students and Scholars

    Visiting students and scholars with computational biology background are welcome to join, salaries and subsidies are negotiable. 

 

About SUSTech

Established in 2012, SUSTech is a public institution funded by Shenzhen, a city with a designated special economic zone status in Southern China bordering Hong Kong. As one of China's key gateways to the world, Shenzhen is the country's fastest-growing city in the past three decades. From a small fishing village 30 years ago to a modern city with a population of over 10 million, the city has become the high-tech and manufacturing hub of southern China. It is home to the world's third-busiest container port and the fourth-busiest airport on the Chinese mainland. Being a picturesque coastal city, Shenzhen is also a popular tourist destination.

SUSTech is a pioneer in higher education reform in China. Its mission is to become a globally recognized institution that excels in research and promotes innovation, creativity, and entrepreneurship. Ninety percent of SUSTech faculty members have overseas work experiences, and sixty percent studied or worked in the top 100 universities in the world. The languages of instruction are English and Chinese. Sitting on five hundred acres of subtropical woodland with hills, rivers, and a natural lake in the Nanshan District of Shenzhen, the SUSTech campus is a beautiful place for learning and research.

          (Credit: Southern University of Science and Technology)

SUSTech is an equal opportunity employer and does not discriminate based on race, religion, color, national origin, sex, gender identity, sexual orientation, veteran status, disability, or any other status protected by the law. 

 

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Contact Us

Contact Address

No 1088, Xueyuan Rd., Nanshan District Shenzhen, Guangdong 518055, China

Office Phone

(+86) 0755-88010164

Email

housw@sustech.edu.cn

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