Research Assistant Professor School of Sciences

Gen-Qiang Chen obtained his Bachelor‘s degree in Zhengzhou University in 2010,followed by master degree in 2013 and PhD degree in 2015 in Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (SIOC, CAS) under the supervision of Prof. Min Shi. Then he pursued his Post Doctor study in Southern University of Science and Technology from 2016-2018, during he was supported by the Presidential Excellent Postdoctoral Scholarship of SUSTech. After the Post Doctor study, he was promoted as research asistant professor and became master tutor in Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology.

Personal Profile


His research areas include Organic synthesis, Chiral ligands, Asymmetric catalysis, Asymmetric hydrogenation and so on. He mainly works on the design and synthesis of new chiral ligands and their application in asymmetric catalysis.

Publications Read More

He has published more than ten papers in famous international journals such as JACS,Angew,Chem. Sci.,Chem. Commun. He successively presided over the free exploration project of shenzhen (project number: JCYJ20170817105056467, 300000 CNY) and the national natural science foundation of China youth project (project number: 21901107, 250000 CNY). He developed a series of oxa-spirocyclic ligands and these ligands have been successfully applied in the dynamic kinetic resolution of Bringmann lactone, the asymmetric hydrogenation of unsaturated acids, the green synthesis of the important drug LCZ696.


1. Chen, G.-Q.; Tang, X.-Y.; Shi, M., HOTf mediated cascade reactions of 1-arenoylcyclopropanecarboxylic acids with arenes. Chem. Commun. 2012, 48, 2340-2342.

2. Chen, G.-Q.; Shi, M., Rhodium-catalyzed tandem Pauson-Khand type reactions of 1,4-enynes tethered by a cyclopropyl group. Chem. Commun. 2013, 49, 698-700.

3. Zhang, X.-N.; Chen, G.-Q.; Dong, X.; Wei, Y.; Shi, M., Phosphine-Catalyzed Asymmetric [4+2| Annulation of Vinyl Ketones with Oxindole-Derived α,β-Unsaturated Imines: Enantioselective Syntheses of 2′,3′-Dihydro-1’H-spiro[indoline-3,4′-pyridin -2-ones. Adv. Synth. Catal. 2013, 355, 3351-3357.

4. Chen, G.-Q.; Tang, X.-Y.; Shi, M., Rhodium-catalyzed carbonylative skeleton rearrangement of 1,4-enynes tethered by a cyclopropane group. Synlett 2014, 25, 2311-2315.

5. Chen, G.-Q.; Tang, X.-Y.; Shi, M., Silver(I)-mediated dual cleavage of C-C and C-O bonds in the reaction of diarylmethylenecyclopropanes with tetrahydrofuran. Synthesis of 4-(3-halobut-3-enyloxy)butyl 2,2,2-trifluoroacetate derivatives. Eur. J. Org. Chem. 2014, 2014, 194-197.

6. Chen, G.-Q.; Zhang, X.-N.; Wei, Y.; Tang, X.-Y.; Shi, M., Catalyst-dependent divergent synthesis of pyrroles from 3-alkynyl imine derivatives: A noncarbonylative and carbonylative approach. Angew. Chem., Int. Ed. 2014, 53, 8492-8497.

7. Zhang, X.-N.; Chen, G.-Q.; Tang, X.-Y.; Wei, Y.; Shi, M., Phosphine-Catalyzed Annulations of 4,4-Dicyano-2-methylene-3-butenoates with Maleimides and Maleic Anhydride. Angew. Chem., Int. Ed. 2014, 53, 10768-10773.

8. Pan, D.; Chen, G.-Q.; Tang, X.-Y.; Shi, M., Palladium-catalyzed intramolecular rearrangement of vinylidenecyclopropanes through C-C bond activation. Org. Chem. Front. 2015, 2, 792-796.

9. Chen, G.-Q.; Fang, W.; Wei, Y.; Tang, X.-Y.; Shi, M., Gold(I)-catalyzed dehydrogenative cycloisomerization of 1,5-enynes. Chem. Commun. 2016, 52, 10799-10802.

10. Chen, G.-Q.; Fang, W.; Wei, Y.; Tang, X.-Y.; Shi, M., Divergent reaction pathways in gold-catalyzed cycloisomerization of 1,5-enynes containing a cyclopropane ring: dramatic ortho substituent and temperature effects. Chem. Sci. 2016, 7, 4318-4328.

11. Chen, G.-Q.; Lin, B.-J.; Huang, J.-M.; Zhao, L.-Y.; Chen, Q.-S.; Jia, S.-P.; Yin, Q.; Zhang, X., Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2. J. Am. Chem. Soc. 2018, 140, 8064-8068.

12. Hu, L. a.; Zhang, Y.; Chen, G.-Q.; Lin, B.-J.; Zhang, Q.-W.; Yin, Q.; Zhang, X., CuH-Catalyzed Atropoenantioselective Reduction of Bringmann’s Lactones via Dynamic Kinetic Resolution. Org. Lett. 2019, 21, 5575-5580.

Lab members Read More

Join us

Contact Us

Contact Address

room 602, building 5, Innovation park

Office Phone



Copyright © 2018 All Rights Reserved.