◆ Molecular mechanism of epigenetic proteins

◆ Structural studies involved in DNA methylation of plants

1. Xue C#, Zhang S#, Wan L#, Zhang Z#, Zhang C, Chen H, Peng K, Wang Y, Hu J, Gao X, Du J, Fu X*, Xu S*. Structure-guided reprogramming of DELLA turnover for a sustainable Green Revolution in rice [J]. Nature Communications, 2026, 17(1).

2. Zhang Z#, Li W#, Liu Y#, Chi C#, Nan J, Wang C, Zhu Y, Zhao J, Xue Y, Li Y, Wang P, Zhai J, Du J*. Structural insights into plant DNA CG methylation maintenance by MET1 [J]. Plant Cell, 2025, 37(11).

3. Liu Y#, Zhang Z#, Hu H, Chen W, Zhang F, Wang Q, Wang C, Yan K*, Du J*. Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation [J]. Nature Plants, 2024, 10(3).

4. Zhang Z, Wang X*, Xin J, Ding Z, Liu S, Fang Q, Yang N, Xu R, Cai G*. Architecture of SWI/SNF chromatin remodeling complex[J]. Protein & cell. 2018;9(12):1045-9.

5. 张智慧, 蔡刚. 冷冻电镜分辨率革命[J]. 科学. 2018(1):5-8.

6. Li L, Zhang Z*. Recombinant expression and characterization of yeast Mrc1, a DNA replication checkpoint mediator[J]. Preparative biochemistry & biotechnology. 2019:1-6.

7. Wang C#, Chi C#, Liu Y, Zhao J, Wang Q, Wang N, Zhang Z, Jiang K, Xue Y, Li Y, Wang P, Zhai J, Guo H, Du J*. Molecular basis of DRB4-assisted long RNA processing and 21-nucleotide siRNA biogenesis by DCL4 in plants [J]. Nature Plants, 2026, 12(3).

8. Xin J#, Xu Z#, Wang X#, Tian Y, Zhang Z, Cai G*. Structural basis of allosteric regulation of Tel1/ATM kinase[J]. Cell research. 2019;29(8):655-65.

9. Zhang X, Wang X *, Zhang Z, Cai G *. Structure and functional interactions of INO80 actin/Arp module[J]. J Mol Cell Biol. 2019;11(5):345-55.

10.Wu T, Zhang Z, Wang X*. Preparation of endogenous TopBP1/Dpb11 and effect on central checkpoint kinase Mecl-Ddc2 (human ATR-ATRIP homolog) [J]. Biochem Bioph Res Co, 2019, 517(2): 291-6.

11. Wang X*, Ahmad S, Zhang Z, Cote J, Cai G*. Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex[J]. Nat Commun. 2018;9(1):1147.

12. Wang X#, Ran T#, Zhang X, Xin J, Zhang Z, Wu T, Wang W, Cai G*. 3.9 A structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP[J]. Science. 2017;358(6367):1206-9.

13. Wang X, Chu H, Lv M, Zhang Z, Qiu S, Liu H, Shen X, Wang W*, Cai G*. Structure of the intact ATM/Tel1 kinase[J]. Nat Commun. 2016;7:11655.

14. Jia N, Liu N, Cheng W, Jiang Y, Sun H, Chen L, Peng J, Zhang Y, Ding Y, Zhang Z, Wang X, Cai G, Wang J, Dong M, Zhang Z, Wu H, Wang H*, Chen Y*, Zhou C*. Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein[J]. EMBO reports. 2016;17(2):235-48.