刘晓天

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科研项目

研究副教授 |生命科学学院, 神经生物学系

刘晓天，神经生物学系，张明杰院士课题组研究副教授，硕士生导师。本科毕业于中国科学技术大学生命科学学院，随后在香港科技大学先后毕业于生物化学系，生物医药工程系，获得硕士，博士学位。2020年9月加入生命科学学院，张明杰院士课题组。

个人简介

工作经历：

刘晓天，博士，硕士生导师。2020年9月加入生命科学学院，张明杰院士课题组。先后担任研究助理教授，研究副教授。主要从事生物大分子结构与功能的研究。

学习经历：

2003-2008，中国科学技术大学，生物技术，学士；

2013-2015，香港科技大学，生物化学，硕士；

2015-2019，香港科技大学，生物医药工程，博士。

所获荣誉：

Hong Kong Technology Talent Scheme Postdoctoral Hub for ITF, 2020;

Chan Tak Kei & Wong Kwai Ying Bioengineering Student Research Award, 2019;

HKJEBN Scholarship for Talents, 2016-2019.

个人简介

研究领域

1.蛋白质机器的三维结构解析及其生物学功能研究

2.生物大分子自组装的分子机制

3.蛋白质凝聚体的解码与编程

学术成果查看更多

Xinlin Hu^#, Ping Yang^#, Changdong Chai, Jia Liu, Huanhuan Sun, Yanan Wu, Mingjie Zhang, Min Zhang^*, Xiaotian Liu^*& Hongjun Yu^*. (2023) “Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1” Nature 616(7955):190-198.
Shuang Fu^#, Wei Shi^#, Tingdan Luo, Yingchuan He, Lulu Zhou, Jie Yang, Zhichao Yang, Jiadong Liu, Xiaotian Liu, Zhiyong Guo, Chengyu Yang, Chao Liu, Zhen-li Huang, Jonas Ries, Mingjie Zhang, Peng Xi, Dayong Jin & Yiming Li^*. (2023) “Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging” Nat Methods.20(3):459-468.
Yanan Wu^#, Min Zhang^#, Yizheng Yang^#, Xuyang Ding, Ping Yang, Kai Huang, Xinlin Hu, Mingjie Zhang, Xiaotian Liu^*& Hongjun Yu^*. (2022)^“Structures and mechanism of chitin synthase and its inhibition by antifungal drug Nikkomycin Z” Cell Discov. 8(1): 129.
Bojing Jiang^#, Xiaotian Liu^#, Chao Yang^#, Zhongguang Yang, Jiren Luo, Songzi Kou, Kai Liu, and Fei Sun^*. (2020) “Injectable, photoresponsive hydrogels for axon regeneration enabled by metal-directed protein assembly”Science Advances. 6 (41): eabc4824.
Songzi Kou, Xin Yang, Zhongguang Yang, Xiaotian Liu, SV Wegner, Fei Sun^*. (2019) “Cobalt-Cross-Linked, Redox-Responsive Spy Network Protein Hydrogels” ACS Macro Letters. 8(7):773-778.
Xiaotian Liu, Xin Yang, Zhongguang Yang, Jiren Luo, X Tian, Kai Liu, Songzi Kou, Fei Sun^*. (2018) “Versatile engineered protein hydrogels enabling decoupled mechanical and biochemical tuning for cell adhesion and neurite growth”ACS Applied Nano Materials. 1(4):1579-1585.
A Tyagi, Xiaotian Liu, I Abidi, Z Gao, B Park, X Zeng, X Ou, A Cagang, M Zhuang, M Hossain, K Zhang, L Weng, F Sun, Z Luo^*. (2018) “Modular functionalization of crystalline graphene by recombinant proteins: a nanoplatform for probing biomolecules” Nanoscale. 10(47):22572-22582.
Jiren Luo, Xiaotian Liu, Zhongguang Yang, Fei Sun^*. (2018) “Synthesis of Entirely Protein-Based Hydrogels by Enzymatic Oxidation Enabling Water-Resistant Bioadhesion and Stem Cell Encapsulation”. ACS Applied Bio Materials.1(5):1735-1740.
Wei Zhiyi^#, Xu Zhiwen^#, Liu Xiaotian, Lo WS, Ye F, Lau CF, Wang F, Zhou JJ, Nangle LA, Yang XL, Zhang Mingjie^*, Schimmel P^*. (2016) “Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase”Nucleic Acids Res. 44(3):1247-55.
Wei Zhiyi^#,Liu Xiaotian^#, Yu Cong, Zhang Mingjie^*. (2013) “Structural basis of cargo recognitions for class V myosins” PNAS. 110(28):11314-9.
Wu Minhao^#, Tao Yue^#, Liu Xiaotian, Zang Jianye^*. (2013) “Structural basis for phosphorylated autoinducer-2 modulation of the oligomerization state of the global transcription regulator LsrR from Escherichia coli” JBC.288(22):15878-87.
Liu Xiaotian, Wu Minhao, Sun Demeng, Zang Jianye^*. (2010) “Cloning, purification, crystallization and preliminary crystallographic analysis of LsrR from Escherichia coli” Acta F. 66(Pt 8):913-5.