Research Assistant Professor |School of Life Sciences, Department of Neuroscience
I graduated from Sichuan University in 2013 for bachelor's degree and Peking University Shenzhen Graduate School for Ph.D. degree in 2019. I have been engaged in research on mechanisms of neurological disorders such as autism and schizophrenia for about 10 years. I have published 8 SCI papers in the field of neuroscience as corresponding author or first author. In addition, I have received two fundings including National Foundation of China-Youth Project and Guangdong Regional Joint Fund-Youth Project. My current research interests are to improve social deficits in autism mouse model using different methods including 40 Hz light flicker and gene intervention.
Personal Profile
Professional Experience:
◆2023/10-now Research Assistant Professor, School of Life Sciences, Southern University of Science and Technology
◆2021/8-2023/9 Research Associate, School of Life Sciences, Southern University of Science and Technology
◆2019/6-2021/6 Postdoc, The Seventh Affiliated Hospital, Sun Yat-sen University
Educational Background:
◆2013/9-2019/1 Peking University Shenzhen Graduate School, Chemical genomics Ph.D.
◆2009/9-2013/6 Sichuan University, Biotechnology, Bachelor
Honors & Awards:
◆ Zhongying Scholarship of Peking University
Research
Exploring E-I imbalance in prefrontal cortex of autistic and schizophrenic mice by electrophysiological recordings and ameliorating E-I imbalance as well as behavioral impairment in autistic and schizophrenic mice by different means, including 40 Hz flash, pharmacological and genetic interventions.
Publications Read More
- Jun Ju#, Xuanyi Li#, YifanPan, Jun Du, Xinyi Yang, Siqi Men, Bo Liu, Zhenyu Zhang, Haolin Zhong, Jinyuan Mai, Yizheng Wang, Sheng-Tao Hou*. Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11.2+/- female mice. In revision in Molecular Psychiatry.
- Jin Zhang#, Weifen Li#, Qi Yue, Luping Liu, Sheng-Tao Hou*, Jun Ju*. Rapamycin exerts an antidepressant effect andenhances myelination in the prefrontal cortex of chronic restraint stress mice. Neuroscience. 2023 Nov 4;535:99-107.
- Luping Liu#, Yujie Zhang#, Siqi Men, Xuanyi Li, Sheng-Tao Hou*, Jun Ju*. Elimination of perineuronal nets in CA1 disrupts GABA release and long-term contextual fear memory retention. Hippocampus. 2023 Jul;33(7):862-871.
- Jun Ju#, Luping Liu#, Xinyi Yang, Siqi Men, Sheng-Tao Hou*.Distinctive effects of NMDA receptor modulators on cerebral microcirculation in a schizophrenia mouse model. Biochemical and Biophysical Research Communications 653 (2023) 62-68.
- Luping Liu, Yujie Zhang, Jun Ju*. Removal of perineuronal nets leads to altered neuronal excitability and synaptic transmission in the visual cortex with distinct time courses. Neurosci Lett. 2022 Aug 10;785:136763.
- Jian Jiang#, Jun Ju#, Liang Luo#al, Huiliang Li*and Ningning Li*. Salmon Calcitonin Exerts an Antidepressant Effect by Activating Amylin Receptors. Front Pharmacol. 2022 Feb 14:13:826055.
- Jun Ju#, Xiuyan Yang#, Jian Jiang#al, Huiliang Li*, Ningning Li*. Structural and lipidomic alterations of striatal myelin in 16p11.2 deletion mouse model of autism spectrum disorder. Front Cell Neurosci. 2021;15:718720.
- Jun Ju, Luping Liu, Yujie Zhang, Qiang Zhou*. Effect of age onset on schizophrenia-like phenotypes and underlying mechanisms in model mice. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:465-474.
- Jun Ju#, Qian Liu#, Yang Zhang et.al Hedong Li*. Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Sci Rep. 2016 Jul 29;6:30711.