Assistant Professor |School of Life Sciences, Department of Chemical Biology Research Group
Dr. Shujun Cai obtained her BSc degree from Beijing Normal University (China) in 2013 and Ph.D. degree from National University of Singapore in 2018. She did her postdoctoral work at Yale University. In 2023, she joined Southern University of Science and Technology (SUSTech) as an Assistant Professor. Her work focuses on using cryo-Electron Tomography (cryo-ET) and cryo-Focused Ion Beam (cryo-FIB) to understand the in-situ structure and mechanism of membrane-remodeling related macromolecules.
Personal Profile
Research
◆In situ structural mechanism of protein-mediated membrane remodeling;
◆Cryo-ET method development;
Publications Read More
- Cai, S., Wu, Y., Guillen-Samander, A., Hancock-Cerutti, W., Liu, J., and De Camilli, P. (2022). In situ architecture of the lipid transport protein VPS13C at ER-lysosome membrane contacts. Proc Natl Acad Sci U S A119, e2203769119.
- Tan, Z.Y.*, Cai, S.*, Noble, A.J.*, Chen, J.K.*, Shi, J., and Gan, L. (2023). Heterogeneousnon-canonical nucleosomes predominate in yeast cells in Elife. 2023 Jul 28;12:RP87672. (*: equal contribution)
- Cai, S.*, Bock, D.*, Pilhofer, M., and Gan, L. (2018). The in-situ structures of mono-, di-, and trinucleosomes in human heterochromatin. Mol Biol Cell29, 2450-2457. (*: equal contribution)
- Cai, S., Chen, C., Tan, Z.Y., Huang, Y., Shi, J., and Gan, L. (2018). Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo. Proc Natl Acad Sci U S A115, 10977-10982.
- Cai, S., Song, Y., Chen, C., Shi, J., and Gan, L. (2018). Natural chromatin is heterogeneous and self-associates in vitro. Mol Biol Cell 29, 1652-1663
Contact Us
Contact Address
2nd Research Building, Rm 310 1088 Xueyuan Blvd, SUSTech Shenzhen, China
Office Phone
caisj@sustech.edu.cn