Chen Zhang

2018-09-02

Education

Master of Science (2015-2018)
-Chemical Biology, School of Chemistry, Sun Yat-sen University.
-Research interest: Metal-based bio-imaging agents.
-Supervisor: Prof. JI Liangnian

Bachelor of Science (2011-2015)
-Chemical Biology, School of Chemistry, Sun Yat-sen University.
-Research interest: Photodynamic anticancer metallodrugs.

Journal Papers

  1. Menglei Zha, Guang Yang,* Yaxi Li, Chen Zhang, Bo Li,* Kai Li,* Recent Advances in AIEgen-Based Photodynamic Therapy and Immunotherapy. Adv. Healthcare Mater. 2021, 2101066-2101081.
  2. Tianyi Kang, Jen-Shyang Ni, Tingting Li, Jun Wang, Zeshun Li, Yaxi Li, Menglei Zha, Chen Zhang, Xue Wu, Heng Guo, Lei Xi, Kai Li.* Efficient and Precise Delivery of MicroRNA by Photoacoustic Force Generated from Semiconducting Polymer-Based Nanocarriers. Biomaterials 2021, 275, 120907 (contributed equally).
  3. Fei Ren, Zeshun Li, Kai Li,* Xiaoyan Zheng,* Jianbing Shi,* Chen Zhang, Heng Guo, Bin Tong, Lei Xi, Zhengxu Cai, Yuping Dong.* Donor Strategy for Promoting Nonradiative Decay to Achieve an Efficient Photothermal Therapy for Treating Cancer. Sci. China Chem. 2021, doi: 10.1007/s11426-021-1055-0 (contributed equally).
  4. Weizhi Qi, Tingting Li, Chen Zhang, Fei Liu, Jun Wang, Dandan Chen, Xiaofeng Fang, Changfeng Wu,* Kai Li,* Lei Xi.* Light-Controlled Precise Delivery of NIR-Responsive Semiconducting Polymer Nanoparticles with Promoted Vascular Permeability. Adv. Healthcare Mater. 2021, doi: 10.1002/adhm.202100569 (contributed equally).
  5. Zeshun Li, Tingting Li, Chen Zhang, Jen-Shyang Ni, Yaoyao Ji, Aihui Sun, Dinglu Peng, Weijun Wu, Lei Xi,* Kai Li.* A Multispectral Photoacoustic Tracking Strategy for Wide-field and Real-time Monitoring of Macrophages in Inflammation. Anal. Chem. 2021, 93, 8467-8475 (contributed equally).
  6. Hao Chen, Huaxiao Yang, Chen Zhang, Si Chen, Xin Zhao, Mark Zhu, Zhiming Wang, Yuebing Wang, Hung-Ta Wo, Kai Li,* Zhen Cheng.* Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by A Molecular NIR-II Cell Tracker. Research 2021, 2021, 9798580 (contributed equally).
  7. Jun Wang, Tingting Li, Jen-Shyang Ni, Heng Guo, Tianyi Kang, Zeshun Li, Menglei Zha, Songbo Lu, Chen Zhang, Weizhi Qi, Lei Xi,* Kai Li.* Photoacoustic force-guided precise and fast delivery of nanomedicine with boosted therapeutic efficacy. Adv. Sci. 2021, doi: 10.1002/advs.202100228 (contributed equally).
  8. Tian Jin, Chen Zhang, Fei Liu, Xingxing Chen, Guangru Liang, Fei Ren, Suzi Liang, Chaolong Song, Jianbing Shi, Weibao Qiu, Xingyu Jiang, Kai Li, Lei Xi,* Anal. Chem. 2021, doi: 10.1021/acs.analchem.0c05218.
  9. Chen Zhang, Kangqiang Qiu, Chaofeng Liu, Huaiyi Huang, Thomas W. Rees, Liangnian Ji, Qianling Zhang* and  Hui Chao*, “Tracking mitochondrial dynamics during apoptosis with phosphorescent fluorinated iridium(III) complexes”. Dalton Transactions. 2018, Advance Article 
  10. Jiangping Liu, Chen Zhang, Thomas W. Rees, Libing Ke, Liangnian Ji and Hui Chao*, “Harnessing ruthenium(II) as photodynamic agnets: encouraging advances in cancer therapys”. Coordination Chemistry Reviews. 363(2018):17-28.
  11. ZHANG Chen, GUAN Ruilin, CHEN Yu, JI Liangnian, CHAO Hui*, “Progress in metal complex-based luminescent probes for small biological molecules.” Progress in Pharmaceutical Sciences, 41 (2017):17-29. (in Chinese)
  12. Yu Chen†, Ruilin Guan†(equal contributors), Chen Zhang, Juanjuan Huang, Liangnian Ji, Hui Chao*, “Two-photon luminescent metal complexes for bioimaging and cancer phototherapy.”Coordination Chemistry Reviews. 310(2016):16-40.

Research

Research Assistant (2018-present)

Prof. LI Kai’s Lab, Southern University of Science and Technology

 

Graduated Research Student (2015-2018)

Prof. JI Liangnian’s Lab, Sun Yat-sen University

  • Designed and synthesized a series of cyclometalated iridium(III) complexes with fluoro ligands and worked on their PDT activities
  • Designed two kinds of protein nanocages (BSA and apo-ferritin) encapsulated iridium-based metallodrugs for anticancer

 

Undergraduate Research Student (2014-2015)

Prof. JI Liangnian’s Lab, Sun Yat-sen University

  • Designed and synthesized a series of cyclometalated iridium(III) complexes worked on their antitumor mechanisms