Direct preparation of unprotected aminimides (R3N+–NH–) from natural aliphatic tertiary alkaloids (R3N) by [Mn(TDCPP)Cl]-catalysed N-amination reaction

2020-08-12

9.  A panel of natural aliphatic tertiary alkaloids (R3N) were directly converted to R3N+–NH (without the need to prepare protected aminimides R3N+–NR′ followed by deprotection) by [Mn(TDCPP)Cl]-catalysed N-amination reaction, with O-(2,4-dinitrophenyl)hydroxylamine as the nitrogen source, in up to 98% yields under mild reaction conditions. (Chemical Communications 202056, 9102–9105.  DOI: 10.1039/D0CC02934C)