陈文东
南方科技大学前沿与交叉科学研究院研究助理教授。2015年于中国科学院大连化学物理研究所获得博士学位，师从李海洋研究员。同年加入南方科技大学从事博士后研究，师从田瑞军研究员，出站后留校工作，担任前沿与交叉科学研究院研究助理教授。具备离子阱质谱和飞行时间质谱仪器研发背景，攻读博士期间研制了2台离子阱质谱仪和1台飞行时间质谱仪。具有丰富的集成化蛋白质组学样品前处理技术开发和高灵敏度磷酸化蛋白质组学研究经验。截止目前为止，以第一作者在Anal. Chem.、J. Chromatogr. A、Analyst等杂志上发表 SCI 论文7篇，中文核心期刊1篇；申请专利9项，其中3项国内发明专利已授权，1项为PCT国际专利。
去向：广州市“慧眼工程”主管
论文
W. N. Gao,‡ Q. Y, Zhang,‡ Y. R. Su, P. W. Huang, X, Lu, Q. Y. Gong, W. D. Chen, R. L. Xu, R. J. Tian,* Multiomic Analysis of Dried Single-Drop Plasma Sample by Integrated Mass Spectrometry Approach, Analyst, Accepted.
Q. Kong,‡ P. W. Huang,‡ B. Z. Chu, M. Ke, W. D. Chen, Z. D. Zheng, S. P. Ji, Z. W. Cai, P. F. Li, and R. J. Tian,* High-Throughput and Integrated Chemical Proteomic Approach for Profiling Phosphotyrosine Signaling Complexes, Anal. Chem., 2020, 92, 8933-8942.
X. Lu,‡ Z. K. Wang,‡ Y. Gao, W. D. Chen, L. J. Wang, P. W. Huang, W. N. Gao, M. Ke, A. He, and R. J. Tian,* AutoProteome Chip System for Fully Automated and Integrated Proteomics Sample Preparation and Peptide Fractionation, Anal. Chem., 2020, 92, 8893-8900.
X. T. Ye,‡ J. Tang,‡ Y. H. Mao,‡ X. Lu, Y. Yang, W. D. Chen, X. Y. Zhang, R. L. Xu, R. J. Tian,* Integrated Proteomics Sample Preparation and Fractionation: Method Development and Applications, TrAC Trends Anal. Chem., 2019, 120, 115667. (Highlighted as Front Cover; Invited Review)
W. N. Gao,‡ H. J. Li,‡ L. P. Liu, P. W. Huang, Z. K. Wang, W. D. Chen, M. L. Ye, X. F. Yu, R. J. Tian,* An Integrated Strategy for High-sensitive and Multi-level Glycoproteome Analysis from Low Micrograms of Protein Samples, J. Chromatogr. A, 2019, 1600, 46-54.
M. Ke,‡ J. Liu,‡ W. D. Chen, L. Chen, W. N. Gao, Y. Q. Qin, A. He, B. Z. Chu, J. Tang, R. L. Xu, Y. Deng,* R. J. Tian,* Integrated and Quantitative Proteomic Approach for Charting Temporal and Endogenous Protein Complexes, Anal. Chem., 2018, 90, 12574-12583.
L. Lin,* J. X. Zheng, Q. Yu, W. D. Chen, J. C. Xing, C. C. Chen, R. J. Tian,* High Throughput and Accurate Serum Proteome Profiling by Integrated Sample Preparation Technology and Single-Run Data Independent Mass Spectrometry Analysis, J. Proteomics, 2018, 174, 9-16.
W. D. Chen, L. Chen, R. J. Tian,* An Integrated Strategy for Highly Sensitive Phosphoproteome Analysis from Low Micrograms of Protein Samples, Analyst, 2018, 143, 3693-3701. (Invited Contribution)
X. Lu,‡ L. Lin,‡ W. B. Zhou,‡ W. D. Chen, J. Tang, X. J. Sun, P. W. Huang, R. J. Tian,* Mixed-Mode Ion Exchange-Based Integrated Proteomics Technology for Fast and Deep Plasma Proteome Profiling, J. Chromatogr. A, 2018, 1564, 76-84.
X. Lu,‡ L. Lin,‡ W. B. Zhou,‡ W. D. Chen, J. Tang, X. J. Sun, P. W. Huang, R. J. Tian,* Mixed-Mode Ion Exchange-Based Integrated Proteomics Technology for Fast and Deep Plasma Proteome Profiling, J. Chromatogr. A, 2018, 1564, 76-84.
X. Zhang,‡ W. D. Chen,‡ Z. B. Ning, J. Mayne, D. R. Mack, A. Stintzi,* R. J. Tian,* D. Figeys,* Deep Metaproteomics Approach for the Study of Human Microbiomes, Anal. Chem., 2017, 89, 9407-9415.
W. D. Chen, S. Adhikari, L. Chen, L. Lin, H. Li, S. S. Luo, P. Y. Yang, R. J. Tian,* 3D-SISPROT: A Simple and Integrated Spintip-Based Protein Digestion and Three-Dimensional Peptide Fractionation Technology for Deep Proteome Profiling, J. Chromatogr. A, 2017, 1498, 207-214.
J. Tang,‡ K. Z. Guo,‡ W. D. Chen, P. P. Song, S. Feng, C. F. Hu, R. L. Xu,* R. J. Tian,* A Fe3O4/EDTA Magnetic Beads-Based Integrated Method for Proteomic Analysis, Chinese J. Chromatogr., 2016, 34, 1263-1269. (Invited Contribution)
W. D. Chen, S. Wang, S. Adhikari, Z. H. Deng, L. J. Wang, L. Chen, M. Ke, P. Y. Yang, R. J. Tian,* Simple and Integrated Spintip-based Technology Applied for Deep Proteome Profiling, Anal. Chem., 2016, 88, 4864-4871.
P. P. Song, P. W. Huang, T. J. Huang, H. Li, W. D. Chen, L. Lin, S. Feng,* R. J. Tian,* Facile Synthesis of Carboxymethyl-β-Cyclodextrin Conjugated Magnetic Nanoparticles for Selective Enrichment of Glycopeptides, Rapid Commun. Mass Spectrom., 2016, Suppl 1, 190-195.