Dr. ZHANG Zhihan (Postdoc)



Zhihan received his B. Sc. in 2016 from Sun Yat-sen University (SYSU) under the supervision of Prof. Zhuofeng Ke. He obtained his Ph.D. in 2020 from The Hong Kong University of Science and Technology (HKUST) under the guidance of Prof. Zhenyang Lin. In October 2020, he joined Prof. Yu’s group as a post-doctoral fellow at Southern University of Science and Technology (SUSTech). His research interests focus on the reaction mechanisms of asymmetric radical transformations, first-row transition metal catalysis, and organocatalysis.


  1.  Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides

Wu, L. ‡, Zhang, Z. ‡; Wu, D. ; Wang, F.; Chen, P.; Lin, Z.*; Liu, G.* (contributted equally)

Angew. Chem. Int. Ed. 2021, 61, 6997-7001. DOI: 10.1002/anie.202015083


  1. 1,4-Selective Hydrovinylation of Diene Catalyzed by an Iron Diimine Catalyst: A Computational Case Study on Two-State Reactivity

Zhang, Z.; Zhang, J.-X.; Sheong, F. K.*; Lin, Z.* (contributted equally)

ACS Catal. 2020, 10, 12454-12465. DOI: 10.1021/acscatal.0c03535


  1. A Study of the Reactivity of (Aza-)Quinone Methides in Selective C6-Alkylations of Indoles

Yan, J.; Zhang, Z.; Chen, M.; Lin, Z.*; Sun, J.* (contributted equally)

ChemCatChem 2020, 12, 5053-5057. 10.1002/cctc.202000850


  1. Enantioselective Copper-Catalyzed Alkynylation of Benzylic C–H Bonds via Radical Relay

Fu, L.; Zhang, Z.; Chen, P.; Lin, Z.*; Liu, G.* (contributted equally)J.Am. Chem. Soc. 2020,142, 12493-12500.  DOI: 10.1021/jacs.0c05373


  1. Three-Pronged Attack by Homologous Far-red/NIR AIEgens to Achieve 1+1+1>3 Synergistic Enhanced Photodynamic Therapy

Xu, W.; Lee, M. M. S.; Nie, J.-J.; Zhang, Z.; Kwok, R. T. K.; Lam, J. W. Y.; Xu, F.-J.; Wang, D.*; Tang, B. Z.*

Angew. Chem. Int. Ed. 2020, 59, 9610-9616. DOI: 10.1002/anie.202000740


  1. Site-specific Allylic C–H bond Functionalization with a Copper-bound N-centred Radical

Li, J.; Zhang, Z.; Wu, L.; Zhang, W.; Chen, P.; Lin, Z.*; Liu, G.*

Nature 2019, 574, 516-521.  DOI: 10.1038/s41586-019-1655-8


  1. Organocatalytic Enantioselective Functionalization of Unactivated Indole C(sp3)−H Bonds.

Ma, D.; Zhang, Z.; Chen, M.; Lin, Z.*; Sun, J.*

Angew. Chem. Int. Ed. 2019, 58, 15916-15921. DOI: 10.1002/ange.201909397


  1. Facile Synthesis of AIEgens with Wide Color Tunability for Cellular Imaging and Therapy.

Xu, W.; Lee, M. M. S.; Zhang, Z.; Sung, H. H. Y.; Williams, I. D.; Kwok, R. T. K.; Lam, J. W. Y.; Wang, D.*; Tang, B. Z.*

Chem. Sci. 2019, 10, 3494-3501. DOI: 10.1039/C8SC05805A


  1. DFT study of CO2Hydrogenation Catalyzed by a Cobalt-base System: an Unexpected Formate Anion-Assisted Deprotonation Mechanism.

Zhang, Z.; Li, Y.; Hou, C.; Zhao, C.; Ke, Z.*

Catal. Sci. Technol. 2018, 8, 656-666. DOI: 10.1039/C7CY02012K 


  1. Mechanistic Studies on the Palladium-Catalyzed Cross-Dehydrogenative Coupling of 4-Phenoxy-2-Coumarins: Experimental and Computational insights.

Prendergast, A. M.; Zhang, Z.; Lin, Z.*; McGlacken, G. P.*

Dalton Trans. 2018, 47, 6049-6053. DOI:  10.1039/C8DT00842F


  1. DFT Study of Acceptorless Alcohol Dehydrogenation Mediated by Ruthenium Pincer Complexes: Ligand Tautomerization Governing Metal Ligand Cooperation.

Hou, C.; Zhang, Z.; Zhao, C.; Ke, Z.*

Inorg. Chem. 2016, 55, 6539-6551. DOI: 10.1021/acs.inorgchem.6b00723


  1. General H2Activation Modes for Lewis Acid–Transition Metal Bifunctional Catalysts.

Li, Y.; Hou, C.; Jiang, J.; Zhang, Z.; Zhao, C.; Page, A. J.; Ke, Z.*

ACS Catal. 2016, 6, 1655-1662. DOI: 10.1021/acscatal.5b02395


  1. Unusual non-bifunctional mechanism for Co-PNP complex catalyzed transfer hydrogenation governed by the electronic configuration of metal center.

Hou, C.; Jiang, J.; Li, Y.; Zhang, Z.; Zhao, C.; Ke, Z*.

Dalton Trans. 2015, 44, 16573-16585. DOI: 10.1039/C5DT02163D 


  1. Hydrogenation of Carbon Dioxide Using Half-Sandwich Cobalt, Rhodium, and Iridium Complexes: DFT Study on the Mechanism and Metal Effect.

Hou, C.; Jiang, J.; Zhang, S.; Wang, G.; Zhang, Z..; Ke, Z.*; Zhao, C.*

ACS Catal. 2014, 4, 2990-2997. DOI: 10.1021/cs500688q