Research Associate professor |School of Life Sciences, Department of Chemical Biology
Personal Profile
Professional Experience:
◆ 2023- now: Southern university of technology, School of life science, Research Associate professor
◆ 2019-2023: Shenzhen Bay laboratory, BayRay Innovation Center, Assistant Researcher
◆ 2014-2018: The Chinese University of Hong Kong, School of life science, PostDoc
Educational Background:
◆ 2008/09-2014/06: University of Science and Technology of China, Ph.D.
◆ 2004/09-2008/06: Henan University, BSc
Honors & Awards:
◆2020 Shenzhen Overseas High-Caliber Personnel (Level C)
◆2014 Zhu Li Yuehua Scholarship of Outstanding Doctoral Award, USTC
◆2012 The Second Prize of Young Scientist Program, Annual meeting of the Chinese Society of Biochemistry and Molecular Biology
◆2011 DongGang Scholarship for Outstanding Graduate Students, USTC
Research
◆ The molecular mechanism studies of novel drug target proteins;
◆ Structure and function based drug discovery and development.
Publications Read More
- Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC*. Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase. Int J Mol Sci. 2021 Oct 27;22(21):11598.
- Shou JW, Cheung CK, Gao J, Shi WW*, Shaw PC*. Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation. Front Cell Neurosci. 2019 Sep 3;13:395.
- Shi WW, Wong KB, Shaw PC*. Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein. Toxins. 2018 Aug 20;10(8):335.
- Shi WW, Mak AN, Wong KB, Shaw PC*. Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins. Molecules. 2016 Nov 21;21(11):1588.
- Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC*. Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2. Toxins (Basel). 2016 Oct 13;8(10):296.
- Shi WW#, Jiang YL#, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H*, Chen Y*, Zhou CZ*. Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins. J Biol Chem. 2014 Jul 25;289(30):20898-907.
- Du Y#, Shi WW#, He YX, Yang YH, Zhou CZ* and Chen Y*. Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC. Biochem J. 2011; 436:283-9.