Weiwei SHI

Research Associate professor |School of Life Sciences, Department of Chemical Biology

Personal Profile

Professional Experience:

◆ 2023- now: Southern university of technology, School of life science, Research Associate professor

◆ 2019-2023: Shenzhen Bay laboratory, BayRay Innovation Center, Assistant Researcher

◆ 2014-2018: The Chinese University of Hong Kong, School of life science, PostDoc

 

Educational Background:

◆ 2008/09-2014/06: University of Science and Technology of China, Ph.D.

◆ 2004/09-2008/06: Henan University, BSc

 

Honors & Awards

◆2020  Shenzhen Overseas High-Caliber Personnel (Level C)

◆2014  Zhu Li Yuehua Scholarship of Outstanding Doctoral Award, USTC

◆2012  The Second Prize of Young Scientist Program, Annual meeting of the Chinese  Society of Biochemistry and Molecular Biology

◆2011  DongGang Scholarship for Outstanding Graduate Students, USTC

Research

◆ The molecular mechanism studies of novel drug target proteins;

◆ Structure and function based drug discovery and development.


Publications Read More

  1. Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC*. Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase. Int J Mol Sci. 2021 Oct 27;22(21):11598.
  2. Shou JW, Cheung CK, Gao J, Shi WW*, Shaw PC*. Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation. Front Cell Neurosci. 2019 Sep 3;13:395.
  3. Shi WW, Wong KB, Shaw PC*. Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein. Toxins. 2018 Aug 20;10(8):335.
  4. Shi WW, Mak AN, Wong KB, Shaw PC*. Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins. Molecules. 2016 Nov 21;21(11):1588.
  5. Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC*. Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2. Toxins (Basel). 2016 Oct 13;8(10):296.
  6. Shi WW#, Jiang YL#, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H*, Chen Y*, Zhou CZ*. Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins. J Biol Chem. 2014 Jul 25;289(30):20898-907.
  7. Du Y#, Shi WW#, He YX, Yang YH, Zhou CZ* and Chen Y*. Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC. Biochem J. 2011; 436:283-9.

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Contact Address

Room 503, 5th Floor, Research Building 2, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China

Office Phone

Email

shiww@sustech.edu.cn

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