• Journal Papers

45. Simultaneous Kinetic Resolution and Asymmetric Induction within a Borrowing Hydrogen Cascade Mediated by a Single Catalyst.

    Jin, M. Y.†; Zhou, Y.†; Xiao, D.†; You, Y.; Zhen, Q.; Tao, G.; Yu, P.*; Xing, X.*

     Angew. Chem., Int. Ed.

44. Stereochemical Control via Chirality Pairing: Stereodivergent Syntheses of Enantioenriched Homoallylic Alcohols.

     Gao, S.†; Duan, M.†; Liu, J.; Yu, P.; Houk, K. N.*; Chen, M.*

     Angew. Chem., Int. Ed. 202160, 24096.

43. Organocatalytic enantioselective dearomatization of thiophenes by 1,10-conjugate addition of indole imine methides.

     Li, X.†; Duan, M.†; Yu, P.; Houk, K. N.*; Sun, J.*

     Nat. Commun. 202112, 4881.

42. Radical Anion Promoted Chemoselective Cleavage of Csp2–S Bond Enables Formal Cross-Coupling of Aryl Methyl Sulfones with Alcohols

     Bai, J.†; Wang, T.†; Dai, B.†; Liu, Q.*; Yu, P.*; Jia, T.*

     Org. Lett. 202123, 5761.

41. Spatiotemporal Profiling of Cytosolic Signaling Complexes in Living Cells by Selective Proximity Proteomics.

     Ke, M.; Yuan, X.; He, A.; Yu, P.; Chen, W.; Shi, Y.; Hunter, T.; Zou, P.; Tian, R.*

     Nat. Commun. 202112, 71.

40. Transition-Metal-Free Double-Insertive Coupling of Isocyanides with Arylboronic Acids Enabled Diarylmethanamines.

     Yang, K.; Hu, X.; Li, W.; Qiu, J.; Feng, Q.; Wang, S.; Zhang, G.; Kuang, Z.; Yu, P.*; Song, Q.*

     Cell Reports Physical Science. 20201, 100268.

39. Computational Investigation of the Mechanism of Diels–Alderase PyrI4.

   Zou, Y.; Yang, S.; Sanders, J. N.; Li, W.; Yu, P.; Wang, H.; Tang, Z.; Liu, W.*; Houk, K. N.*

     J. Am. Chem. Soc. 2020, 142, 20230.

38. Streamlined Construction of Silicon-Stereogenic Silanes by Tandem Enantioselective C–H Silylation/Alkene Hydrosilylation.

     Wu, D.†; Yuan, W.†; Chen, S.; Wang, N.; Yang, B.; You, L.; Zu, B.; Yu, P.; He, C.*

     J. Am. Chem. Soc. 2020, 142, 13459.

37. Aqueous Diels–Alder Reactions for Thermochemical Storage and Heat Transfer Fluids Identified Using Density Functional Theory.

     Spotte-Smith, E. W. C.; Yu, P.; Blau, S. M.; Prasher, R. S.*; Jain, A.*

     J. Comput. Chem. 2020, 41, 2137.

36. DFT-Guided Phosphoric-Acid-Catalyzed Atroposelective Arene Functionalization of Nitrosonaphthalene.

     Ding, W.-Y.†; Yu, P.†; An, Q.-J.†; Bay, K. L.†; Xiang, S.-H.; Li, S.; Chen, Y.; Wang, X.; Chen, Y.; Houk, K. N.*; Tan, B.*

     Chem 2020, 6, 2046.

35. Dynamical Trajectory Study of the Transannular [6+4] and Ambimodal Cycloaddition in the Biosynthesis of Heronamides.

     Zhang, C.†; Wang, X.†; Chen, Y.; He, Z.; Yu, P.*; Liang, Y.*

     J. Org. Chem. 2020, 85, 9440.

34. Dual-Ligand-Enabled Ir(III)-Catalyzed Enantioselective C–H Amidation for the Synthesis of Chiral Sulfoxides.

     Liu, W.; Yang, W.; Zhu, J.; Guo, Y.; Wang, N.; Ke, J.; Yu, P.; He, C.*

     ACS Catal. 2020, 10, 7207.

33. Pd-Catalyzed Dearomative Asymmetric Allylic Alkylation of Naphthols with Alkoxyallenes.

     Hu, J.; Pan, S.; Zhu, S.; Yu, P.; Xu, R.; Zhong, G.; Zeng, X.*

     J. Org. Chem. 2020, 85, 7896.

32. Computational Design of Enhanced Enantioselectivity in Chiral Phosphoric Acid Catalyzed Oxidative Desymmetrization of 1,3-Diol Acetals.

     Meng, S.-S.; Yu, P.; Yu, Y.-Z.; Liang, Y.*; Houk, K. N.*; Zheng, W.-H.*

     J. Am. Chem. Soc. 2020, 142, 8506.

31. Chiral Brønsted Acid from Chiral Phosphoric Acid Boron Complex and Water: Asymmetric Reduction of Indoles.

     Yang, K.; Lou, Y.; Wang, C.; Qi, L.-W.; Fang, T.; Zhang, F.; Xu, H.; Zhou, L.; Li, W.; Zhang, G.; Yu, P.*; Song, Q.*

     Angew. Chem., Int. Ed. 2020, 59, 3294.

30. Catalytic Effects of Ammonium and Sulfonium Salts and External Electric Fields on Aza-Diels–Alder Reactions.

     He, C. Q.; Lam, C. C.; Yu, P.; Song, Z.; Chen, M.; Lam, Y.-h.; Chen, S.; Houk, K. N.*

     J. Org. Chem. 2020, 85, 2618.

29. Organocatalytic Atroposelective Construction of Axially Chiral Arylquinones.

     Zhu, S.†; Chen, Y.-H.†; Wang, Y.-B.†; Yu, P.; Li, S; Xiang, S.-H.; Wang, J.; Xiao, J.; Tan, B.*

     Nat. Commun. 201910, 4268.

28. Theoretical Study of Diastereoselective NHC-Catalyzed Cross-Benzoin Reactions between Furfural and N-Boc-Protected α-Amino Aldehydes.

     Duan, A.†; Fell, J. S.†; Yu, P.; Lam, Y.-h.; Gravel, M.*; Houk, K. N.*

     J. Org. Chem. 201984, 13565.

27. Bifunctional Phosphonium Salt Directed Enantioselective Formal [4 + 1] Annulation of Hydroxyl-Substituted para-Quinone Methides with α-Halogenated Ketones.

     Tian, J.-P.†; Yu, P.†; Wu, J.-H.; Chen, Y.; Pan, J.; Jiang, C.; Ren, X.; Zhang, H.-S.; Wang, T.*

     Org. Lett. 201921, 7298.

26. Asymmetric Construction of Axially Chiral 2-Arylpyrroles by Chirality Transfer of Atropisomeric Alkenes.

     Wang, Y.-B.; Wu, Q.-H.; Zhou, Z.-P.; Xiang, S.-H.; Cui, Y.; Yu, P.; Tan, B.*

     Angew. Chem., Int. Ed. 201958, 13443.

25. Atroposelective Construction of Arylindoles by Chiral Phosphoric Acid-Catalyzed Cross-Coupling of Indoles and Quinones.

     Lu, D.-L.; Chen, Y.-H.; Xiang, S.-H.; Yu, P.; Tan, B.; Li, S.*

     Org. Lett. 201921, 6000.

24. Rational Design, Enantioselective Synthesis and Catalytic Applications of Axially Chiral EBINOLs.

     Wang, Y.-B.†; Yu, P.†; Zhou, Z.-P.†; Zhang, J.; Wang, J.; Houk, K. N.*; Tan, B.*

     Nat. Catal. 20192, 504.


Publications before SUSTech

23. Enhanced Thermochemical Heat Capacity of Liquids: Molecular to Macroscale Modeling.

     Yu, P.; Jain, A.*; Prasher, R. S.*

     Nanoscale Microscale Thermophys. Eng. 201923, 235.

22. Ambimodal Dipolar/Diels–Alder Cycloaddition Transition States Involving Proton Transfers.

     Chen, S.; Yu, P.; Houk, K. N.*

     J. Am. Chem. Soc. 2018140, 18124.

21. Organocatalytic [6+4] Cycloadditions via Zwitterionic Intermediates: Chemo-, Regio-, and Stereoselectivities.

     Yu, P.†; He, C. Q†; Simon, A.; Li, W.; Mose, R.; Thøgersen, M. K.; Jørgensen, K. A.; Houk, K. N.*

     J. Am. Chem. Soc. 2018140, 13726.

20. Asymmetric Phosphoric Acid­–Catalyzed Four-Component Ugi Reaction.

     Zhang, J.†; Yu, P.†; Li, S.-Y.; Sun, H.; Xiang, S.-H.; Wang, J.; Houk, K. N.*; Tan, B.*

     Science 2018361, eaas8707.

19. Intramolecular Diels–Alder Approaches to the Decalin Core of Verongidolide: The Origin of the exo-Selectivity, a DFT Analysis.

    Maiga-Wandiam, B; Corbu, A.; Massiot, G.; Sautel, F.; Yu, P.; Lin, B.; Houk, K. N.*; Cossy, J.*

    J. Org. Chem. 201883, 5975.

18. Relationships between Product Ratios in Ambimodal Pericyclic Reactions and Bond Lengths in Transition Structures.

    Yang, Z.†; Dong, X.†; Yu, Y.; Yu, P.; Li, Y.; Jamieson, C.; Houk, K. N.*

    J. Am. Chem. Soc. 2018140, 3061.

17. Influence of Water and Enzyme SpnF on the Dynamics and Energetics of the Ambimodal [6+4]/[4+2] Cycloaddition.

    Yang, Z.†; Yang, S.†; Yu, P.†; Li, Y.†; Doubleday, C.; Park, J.; Patel, A.; Jeon, B.-s.; Russell, W.; Liu, H.-w.; Russell, D.; Houk, K. N.*

    Proc. Natl. Acad. Sci. U. S. A. 2018115, E848.

16. Computational Exploration of Concerted and Zwitterionic Mechanisms of Diels–Alder Reactions between 1,2,3-Triazines and Enamines and Acceleration by Hydrogen-Bonding Solvents.

    Yang, Y.-F.; Yu, P.; Houk, K. N.*

    J. Am. Chem. Soc. 2017139, 18213.

15. Origins of Stereoselectivity in Chiral Aminoalcohol Catalysis of Oxyallyl Cation–Indole Reactions.

    He, C. Q.; Yu, P.; Lam, Y.-h.; Houk, K. N.*

    Org. Lett. 201719, 5685.

14. Mechanisms and Origins of Periselectivity of the Ambimodal [6+4] Cycloadditions of Tropone to Dimethylfulvene.

    Yu, P.; Chen, T. Q.; Yang, Z.; He, C. Q.; Patel, A.; Lam, Y.-h.; Liu, C.-Y.; Houk, K. N.*

    J. Am. Chem. Soc. 2017139, 8251.

13. Mechanisms and Origins of Selectivities of the Lewis Acid-Catalyzed Diels–Alder Reactions between Aryl Allenes and Acrylates.

    Yu, P.†; Li, W.†; Houk, K. N.*

    J. Org. Chem. 201782, 6398.

12. A Theoretical Study of Phosphorescent Cu(I) Complexes with 2-(2'Quinolyl)imidazole and POP Mixed Ligands.

    He, T.; Ren, A; Chen, S.; Yang, Z.; Yu, P.; Chen, Y.; Ding, X.; Shen, L.; Zhang, H.; Zou, L.*

    Org. Electron. 201745, 9.

11. Diazo Esters as Dienophiles in Intramolecular (4+2) Cycloadditions: Computational Explorations of Mechanism.

    Duan, A.; Yu, P.; Liu, F.; Huang, Q.; Gu, F. L.; Doyle, M. P.*; Houk, K. N.*

    J. Am. Chem. Soc. 2017139, 2766.

10. Biochemical Characterization of a Eukaryotic Decalin-Forming Diels–Alderase.

    Li, L.; Yu, P.; Tang, M.-C.; Zou, Y.; Gao, S.-S.; Hung, Y.-S.; Zhao, M.; Watanabe, K.*; Houk, K. N.*; Tang, Y.*

    J. Am. Chem. Soc. 2016138, 15837.

9. Synthesis of 2-Ethenylcyclopropyl Aryl Ketones via Intramolecular SN2-like Displacement of an Ester.

    Jung, M. E.*; Sun, D. L.; Dwight, T. A.; Yu, P.; Li, W.; Houk, K. N.*

    Org. Lett. 201618, 5138.

8. Origins of Regioselectivity in 1,3-Dipolar Cycloadditions of Nitrile Oxides with Alkynylboronates.

    Lin, B.; Yu, P.; He, C. Q.; Houk, K. N.*

    Bioorgan. Med. Chem. 201624, 4787.

7. Distortion-Controlled Reactivity and Molecular Dynamics of Dehydro-Diels–Alder Reactions.

    Yu, P.†; Yang, Z.†; Liang, Y.; Hong, X.; Li, Y.; Houk, K. N.*

    J. Am. Chem. Soc. 2016138, 8247.

6. Molecular Dynamics of Dimethyldioxirane C–H Oxidation.

    Yang, Z.; Yu, P.; Houk, K. N.*

    J. Am. Chem. Soc. 2016138, 4237.

5. Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase.

    Gao, S. S.; Duan, A.; Xu, W.; Yu, P.; Hang, L.; Houk, K. N.*; Tang, Y.*

    J. Am. Chem. Soc. 2016138, 4249.

4. Transannular [6+4] and Ambimodal Cycloaddition in the Biosynthesis of Heronamide A.

    Yu, P.; Patel, A.; Houk, K. N.*

    J. Am. Chem. Soc. 2015137, 13518.

3. Why Alkynyl Substituents Dramatically Accelerate Hexadehydro-Diels–Alder (HDDA) Reactions: Stepwise Mechanisms of HDDA Cycloadditions.

    Liang, Y.; Hong, X.; Yu, P.; Houk, K. N.*

    Org. Lett. 201416, 5702.

2. Catalytic Asymmetric [4+2] Annulation Initiated by an Aza-Rauhut–Currier Reaction: Facile Entry to Highly Functionalized Tetrahydropyridines.

    Shi, Z.; Yu, P.; Loh, T.-P.*; Zhong, G.*

    Angew. Chem., Int. Ed. 201251, 7825.

1. Organocatalytic Asymmetric Synthesis of Protected α, β‐Diamino Acids.

    Shi, Z.; Yu, P.; Chua, P. J.; Zhong, G.*

    Adv. Synth. Catal. 2009351, 2797.

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