张建超

研究助理教授(副研究员) |医学院, 医学院, 生物化学系

理学博士,2013年获东北师范大学博士学位,主要从事肿瘤发生,发展和转移的分子机制研究,涉及生物化学、分子生物学,细胞生物学多个学科领域。目前发表学术论文15篇,包括第一作者论文Clinical and Translational Medicine (2021),Cancer Research(2012)、Oncogene(2020)、Oncotarget(2016)、BBRC(2013)等论文。主持国家自然科学基金1项,中国博士后科学基金1项,广东省自然科学基金1项,深圳市科技项目3项;获得吉林省科学技术奖一等奖1项、吉林省自然科学学术成果二等奖1项、2015年吉林省优秀博士学位论文以及2012年博士生国家奖学金。

个人简介

研究领域

肿瘤发生和转移的分子机制


学术成果 查看更多

(1) Jianchao Zhang, Xiaokai Fan, Lijuan Liao, Yan Zhu, Xiaochun Wan, Hai Rao and Liang Chen1, TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression. Clinical and Translational Medicine, 2021, In press. (中科院JCR一区,Top,IF: 11.493)

(2) Jianchao Zhang, Xinxin Lin, Liufeng Wu, Jia-Jia Huang, Wen-qi Jiang, Thomas Kipps, and Suping Zhang, Aurora B induces epithelial–mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis. Oncogene, 2020, 39(12):2550-2567. (中科院JCR一区,Top,IF: 9.867)

(3) Jianchao Zhang, Ximing Shao, Haiyan Sun, Ke Liu, Zhihao Ding, Juntao Chen, Lijing Fang, Wu Su, Yang Hong, Huashun Li and Hongchang Li, NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling. Oncotarget, 2016, 7(38):61036-53. (中科院JCR一区,IF: 5.01)

(4) Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu, and Baiqu Huang, SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Research, 2012, 72(17):4597-608. (中科院JCR一区,Top,IF: 8.65)

(5) Jianchao Zhang, Yang Lei, Xiaoge Gao, Qian Liang, Lili Li, Jingxin Feng, Yu Zhang, Baiqu Huang, and Jun Lu, p53 attenuates the oncogenic ras-induced epithelial-mesenchymal transition in human mammary epithelial cells. Biochemical and Biophysical Research Communications, 2013, 434(3):606-13. (中科院JCR三区IF: 2.406)

(6) Suping Zhang, Han Zhang, Emanuela M. Ghia, Jiajia Huang, Liufeng Wu, Jianchao Zhang, Sharon Lam, Yang Lei, Jinsong He, Bing Cui, George F. Widhopf II, Jian Yu, Richard Schwab, Karen Messer, Wenqi Jiang, Barbara A. Parker, Dennis A. Carson, and Thomas J. Kipps, Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody. Proc Natl Acad Sci U S A, 2019, 116(4):1370-1377. (中科院JCR一区,Top,IF: 9.504)

(7) Ximing Shao, Yi Liu, Qian Yu, Zhihao Ding, Wenyu Qian, Lei Zhang, Jianchao Zhang, Nan Jiang, Linfei Gui, Zhiheng Xu, Yang Hong, Yifan Ma, Yanjie Wei, Xiaoqing Liu, Changan Jiang, Minyan Zhu, Hongchang Li and Huashun Li, Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b. Cell Research, 2016, 26(5):593-612. (中科院JCR一区,Top,IF: 14.812)

(8) Qian Liang, Lili Li, Jianchao Zhang, Yang Lei, Liping Wang, Dong-Xu Liu, Jingxin Feng, Pingfu Hou, Ruosi Yao, Yu Zhang, Baiqu Huang, and Jun Lu, CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression. Scientific Reports. 2013, 14;3:2932. (中科院JCR三区,IF: 5.078)

(9) Jingxin Feng, Guiying Xu, Jiwei Liu, Na Zhang, Lili Li, Jiafei Ji, Jianchao Zhang, Lian Zhang, Guannan Wang, Xiuli Wang, Jiang Tan, Baiqu Huang, Jun Lu, Yu Zhang, Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer. Breast Cancer Research and Treatment. 2016, 159(3):443-56. (中科院JCR二区,IF: 4.085)

(10) Ke Liu, Lijing Fang, Haiyan Sun, Zhengyin Pan, Jianchao Zhang, Juntao Chen, Ximing Shao, Wei Wang, Yuanyan Tan, Zhihao Ding, Lijiao Ao, Chunlei Wu, Xiaoqi Liu, Huashun Li, Rui Wang, Wu Su, and Hongchang Li, Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo. Molecular Cancer Therapeutics, 2018, 17(5):988-1002. (中科院JCR二区,IF: 5.764)

(11) Ke Liu, Run Lei, Qiong Li, Xin-Xin Wang, Qian Wu, Peng An, Jianchao Zhang, Minyan Zhu, Zhiheng Xu, Yang Hong, Fudi Wang, Ying Shen, Hongchang Li, and Huashun Li, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Scientific Reports. 2016, 16;6:21019. (中科院JCR三区,IF: 5.228)

(12) Ke Liu, Quan Lin, Yanxia Wei, Renbing He, Ximing Shao, Zhihao Ding, Jianchao Zhang, Minyan Zhu, Lee S. Weinstein, Yang Hong, Hongchang Li, Huashun Li, Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression. Neuroscience Letters. 2015, 597:97-103. (中科院JCR四区,IF: 2.107)

(13) Yu Zhang, Yanyan Gao, Guoping Zhang, Shuyan Huang, Zhixiong Dong, Chenfei Kong, Dongmei Su, Juan Du, Shan Zhu, Qian Liang, Jianchao Zhang, Jun Lu and Baiqu Huang, DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells. International Journal of Cancer, 2011, 128:551-61. (中科院JCR二区,IF: 5.444)

(14) Dongmei Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang, Qian Liang, Jun Lu, Baiqu Huang, Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells. Biochemical Journal, 2010, 433(2):333-43. (中科院JCR二区,IF: 4.897)

(15) Hanqing Shi, Hui Huang, Xitao Zhang, Jianchao Zhang, Xiutan Luo, Xiue Peng, Baiqu Huang, Jun Lu, c-Myc attenuates the ability of doxorubicin to reduce the colony formation partially through regulating Nbs1 in U2OS cells. Progress in Biochemistry and Biophysics, 2010, 37(8):855-63. (中科院JCR三区,IF: 0.236)

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