Associate Professor College of Science

主要从事生物化学和结构生物学研究,研究内容涉及疾病相关的重要蛋白的结构与功能,目前研究集中于细胞黏附、分子运输等方面。以第一作者或者通讯作者在国际重要期刊《Cell》、《Molecular Cell》上发表文章。荣获2009年香港科学会颁发的“青年科学家”称号。

Personal Profile

Self-introduction
Dr.Yu’s research work mainly focus on the structural and functional studies of the proteins involved in cell-ECM adhesion, intracellular trafficking and many neuronal diseases, by combining the powerful tools in biochemistry, biophysics and cell biology. The research results have been published on Cell,Molecular Celletc, and Dr.Yu has been awardedHong Kong Young Scientist Award in Life Science (2009) and the Peacock Plan (2014, Shenzhen)

 

Research Interests
◆the structures and functions of proteins involved in cell-ECM(extracellular matrix) adhesion
◆the molecular mechanisms of molecular motors related to disease

 

Professional Experience
◆ 2013-present Associate Professor, Southern University of Science and Technology of China
◆ 2009 –2013   Research Associate in Division of Life Science, the Hong Kong University of Science and Technology

 

Educational Background
◆ Jan. 2004 –Aug. 2009 Ph.D., Biochemistry, the Hong Kong University of Science and Technology
◆ Sep. 1998 – Jun.2003  B.S., Biology, University of Science and Technology of China

 

Honors & Awards
◆Hong Kong Young Scientist Award in Life Science, Hong Kong Institute of Science 2009
◆Postgraduate Achievement Award, Biochemistry, Hong Kong University of Science and Technology 2009
◆Postgraduate Student Research Award, Biochemistry,Hong Kong University of Science and Technology 2009

Research

The structural and functional studies of the core proteins involved in cell and extracellular adhesion

The structural and functional studies of the cytoskeleton motors and regulators


Publications Read More

Li,H.*,Deng,Y.*,Sun,K.,….,Wu,C.#,Wei,Z.#,Yu,C.# (2017) Structural basis of kindlin-mediated integrin recognition and activation. Proc Natl Acad Sci U S A. published ahead of print July 24, 2017,doi: 10.1073/pnas.1703064114

Liang, M., Xie, X., Pan, J., Jin, G., Yu, C. # , and Wei, Z. # (2019). "Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics." J Biol Chem 294(15): 5827-5839.

Wei,Z*.,Zheng,S.*, Spangler,S.A., Yu,C.#, Hoogenraad,C.C., Zhang,M.# (2011) . Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures. Mol Cell 43:586-98. doi: 10.1016/j.molcel.2011.07.021

Yu, C.*, Feng, W.*, Wei, Z., Miyanoiri, Y., Wen, W., Zhao, Y., and Zhang, M.# (2009). Myosin VI Undergoes Cargo-Mediated Dimerization. Cell 138, 537-548. doi: 10.1016/j.cell.2009.05.030.

News More

  • Achievement: Research of Biology Department Published in PNAS

    2018-08-31

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Contact Address

NO.1 Faculty Research

Office Phone

0755-88018410

Email

yuc@sustech.edu.cn

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