Research associated prof. |Academy for Advanced Interdisciplinary Studies

Dr. Qin Yin obtained his B.S. degree in Chemistry from the College of Chemistry and Chemical Engineering, Hunan Normal University in 2009. Then he started his graduate study at Shanghai Institute of Organic Chemistry, CAS under the supervision of Prof Shuli You, where his research focused on asymmetric catalysis. After obtaining his Ph.D. in 2014, he joined Prof. Martin Oestreich’s group at TU Berlin as a postdoctoral researcher under the support of Alexander von Humboldt Foundation, where his research focuses on main-group element chemistry. In June. 2017, Dr. Yin joined Southern University of Science and Technology as an research associate professor to start his research career.

Personal Profile

Research

Development of highly efficient and selective catalysts and strategy for the synthesis of functional molecules;

Sustainable chemistry enabled by base metal;

Modification of drug molecules and evaluation of biological activity.


Publications Read More

Dr. Yin has published over 30 peer-reviewed papers includes 21 pieces as first author or corresponding author.

1. Yongjie Shi, Xuefeng Tan, Shuang Gao, Yao Zhang, Jingxin Wang, Xumu Zhang, and Qin Yin*, Direct Synthesis of Chiral NH Lactams via Ru-Catalyzed Asymmetric Reductive Amination/Cyclization Cascade of Keto Acids/Esters, Org. Lett. 2020, 22, 2707−2713. (IF 6.555, 2020-03-19)

2. Le’ an Hu, Yao Zhang, Qing-Wen Zhang, Qin Yin,* and Xumu Zhang, Ruthenium-Catalyzed Direct Asymmetric Reductive Amination of Diaryl and Sterically Hindered Ketones with Ammonium Salts and H2, Angew. Chem. Int. Ed. 2020, 59, 5321-5325. (IF 12.257, 2020-01-17)

3. Le’an Hu, Yao Zhang, Gen-Qiang Chen, Bi-Jin Lin, Qing-Wen Zhang,* Qin Yin,*and Xumu Zhang*, CuH-Catalyzed Atropoenantioselective Reduction of Bringmann’s Lactones via Dynamic Kinetic Resolution, Org. Lett. 2019, 21, 5575-5580. (IF 6.555, 2019-06-27)

4. Tao Yang, Xiaochong Guo, Qin Yin* and Xumu Zhang*, Intramolecular Asymmetric Reductive Amination: Synthesis of Enantioenriched Dibenz[c,e]azepines, Chem. Sci. 2019, 10, 2473-2477. (IF 9.556, 2018-12-27)

5. Yazhou Lou, Yutao Hu, Jiaxiang Lu, Fanfu Guan, Gelin Gong, Qin Yin*, Xumu Zhang*, Dynamic Kinetic Asymmetric Reductive Amination: Synthesis of Chiral Primary β-amino Lactams, Angew. Chem. Int. Ed. 2018, 57, 14193-14197. (IF 12.257, 2018-09-07)

6. Gen-Qiang Chen, Bi-Jin Lin, Jia-Ming Huang, Ling-Yu Zhao, Qi-Shu Chen, Shi-Peng Jia, Qin Yin* and Xumu Zhang*; Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2. J. Am. Chem. Soc. 2018, 140, 8064–8068. (IF 14.695, 2018-06-19) (Highlighted by Synfacts 2018, 14, 1050.)

7. Qiwei Lang, Guoxian Gu, Yaoti Cheng, Qin Yin* and Xumu Zhang*; Highly Enantioselective Synthesis of Chiral γ-Lactams by Rh-Catalyzed Asymmetric Hydrogenation. ACS Catal. 2018, 8, 4824−4828. (IF 12.221, 2018-04-23 ) (Highlighted by Synfacts 2018, 14, 0832.)

8. Xuefeng Tan, Shuang Gao, Weijun Zeng, Shan Xin, Qin Yin* and Xumu Zhang*; Asymmetric Synthesis of Chiral Primary Amines by Ruthenium-Catalyzed Direct Reductive Amination of Alkyl Aryl Ketones with Ammonium Salts and Molecular H2. J. Am. Chem. Soc. 2018, 140, 2024–2027. (IF 14.695, 2018-01-29) (Highlighted by Synfacts 2018, 14, 0504. and Org. Process Res. Dev. 2018, 22, 421−429.) ESI高被引论文

9. Guoxian Gu, Jiaxiang Lu, Ouran Yu, Jialin Wen,* Qin Yin* and Xumu Zhang*; Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of α‑Substituted β‑Ketoesters via Dynamic Kinetic Resolution. Org. Lett. 2018, 20, 1888−1892. (IF 6.555, 2018-03-20)

10. Tao Yang, Qin Yin, Guoxian Gu and Xumu Zhang *, A one-pot process for the enantioselective synthesis of tetrahydroquinolines and tetrahydroisoquinolines via asymmetric reductive amination (ARA), Chem. Commun., 2018, 54, 7247. (IF 6.164)

11. Qin Yin, Hendrik F. T. Klare*, and Martin Oestreich*; Catalytic Friedel–Crafts C–H Borylation of Electron-Rich Arenes: Dramatic Rate Acceleration by Added Alkenes. Angew. Chem. Int. Ed. 2017, 56, 3712–3717. Highlighted in SYNFACTS 2017, 13, 529. and Org. Process Res. Dev. 2017, 21, 675–688. (IF 12.257, 2017-02-28)

12. Qin Yin* and M. Oestreich*; Photocatalysis Enabling Acceptorless Dehydrogenation of Benzofused Saturated Rings at Room Temperature (Highlight), Angew. Chem. Int. Ed. 2017, 56, 7716–7718. (IF 12.257)

13. Qin Yin, Hendrik F. T. Klare, and Martin Oestreich*; Friedel‒Crafts-type Intermolecular C–H Silylation of Electron-Rich Arenes Initiated by Base Metal Salts. Angew. Chem. Int. Ed. 2016, 55, 3204–3207. (IF 12.257, 2017-01-28)

14. Qin Yin, Shou-Guo Wang, Xiao-Wei Liang, De-Wei Gao, Jun Zheng and Shu-Li You*; Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179–4183. (IF 9.556)

15. Qin Yin and Shu-Li You*; Chiral Phosphoric Acid-Catalysed Friedel–Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones. Chem. Sci. 2011, 2, 1344–1348. (IF 9.556)

16. Qin Yin, Yashar Soltani, Rebecca Melen,* and Martin Oestreich*; BArF3-Catalyzed Imine Hydroboration with Pinacolborane Not Requiring the Assistance of an Additional Lewis Base. Organometallics 2017,36, 2381–2384. (Top 2 most accessed paper in July, 2017.) (IF 4.051)

17. Qin Yin, Sebastian Kemper, Hendrik F. T. Klare, and Martin Oestreich*, Boron Lewis Acid-Catalyzed Hydroboration of Alkenes with Pinacolborane: BArF3 Does What B(C6F5)3 Cannot Do! Chem. Eur. J. 2016, 22, 13840–13844. (IF 5.160)

18. Qin Yin and Shu-Li You*; Asymmetric Chlorocyclization of Indole-3-yl-benzamides for the Construction of Fused-indolines. Org. Lett. 2014, 16, 2426–2429. (IF 6.555)

19. Qin Yin and Shu-Li You*; Asymmetric Chlorination/Ring Expansion for the Synthesis of α-Quaternary Cycloalkanones. Org. Lett. 2014, 16, 1810–1813. (IF 6.555)

20. Qin Yin and Shu-Li You*; Enantioselective Chlorocyclization of Indole Derived Benzamides for the Synthesis of Spiro-indolines. Org. Lett. 2013, 15, 4266–4269. (IF 6.555)

21. Qin Yin, Shou-Guo Wang and Shu-Li You*; Asymmetric Synthesis of Tetrahydro-β-carbolines via Chiral Phosphoric Acid Catalyzed Transfer Hydrogenation Reaction. Org. Lett. 2013, 15, 2688-2691. (IF 6.555)

22. Qin Yin and Shu-Li You*; Intramolecular Alkene Electrophilic Bromination Initiated ipso-Bromocyclization for the Synthesis of Functionalized Azaspirocyclohexadienones. Org. Lett. 2012, 14, 3526–3529. (IF 6.555)

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Email

yinq@sustech.edu.cn

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