Associate Professor College of Science

Yu Chung Tse, Ph.D., Associate Professor.He got his Ph.D. at 2007 in The Chinese University of Hong Kong, and then he worked as Postdoctoral fellow in The University of Chicago for 5 years. Dr. Tse is fully experienced in the research of cell biology, and he is mainly interested on cell division, cell polarity, cell adhesion and developmental biology. His researches are supporting by National Natural Science Foundation of China (NSFC) and Shenzhen Science, Technology and Innovation Commission (SZSTI).

Personal Profile

Research

My lab is mainly interested in cell biology researches. We particularly interested in study cytokinesis, cell adhesion, cell migration and related developmental process. Currently, we use nematode C. elegans and cultured human cells as the model systems and combine with live cell imaging, genetics and biochemistry to address the following problem:

(1) What is the molecular mechanism of cytokinesis?

(2) How does extracellular matrix regulate cytokinesis?

(3) What is the molecular mechanism of cell adhesion and its related developmental process?

(4) What is the molecular mechanism of cell migration?


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1. Li L, Wang S, Lan H, Gong G, Zhu Y, Tse YC#, Wong KM#. Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid. ChemistryOpen 7: 136-143.

2. Li L, Wang C, Wu J, Tse YC#, Cai YP, Wong KM#. (2016) A Molecular Chameleon with Fluorescein and Rhodamine Spectroscopic Behaviors. Inorganic Chemistry 55: 205-213.

3. Basant A, Lekomtsev S, Tse YC, Zhang D, Longhini KM, Petronczki M, Glotzer M. (2015) Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Developmental Cell 33: 204-215

4. Tse YC*, Werner ME, Longhini MK, Labbe JC, Goldstein B, Glotzer M. (2012) RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Molecular Biology of the Cell 23: 4023-4031.

5. Tse YC*, Wang J, Jiang L. (2012) Multivesicular bodies in developing tobacco seed and mung bean are functionally equivalent. Plant Signaling & Behavior 7:1-4.

6. Tse YC*, Piekny A, Glotzer M. (2011) Anillin promotes astral microtubule-directed cortical myosin polarization. Molecular Biology of the Cell 22:3165-3175.

7. Wang J, Tse YC, Hinz G, Robinson DG, Jiang L. (2011) Storage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean. Journal of Experimental Botany 63:1367-1380.

8. Afshar K, Werner ME^, Tse YC^, Glotzer M, Gönczy P. (2010) Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos. Development 137:237-47. (^ these authors contributed equally to this work.)

9. Wang H, Tse YC, Law AH, Sun SS, Sun YB, Xu ZF, Hillmer S, Robinson DG, Jiang L. (2010) Vacuolar sorting receptors (VSRs) and secretory carrier membrane proteins (SCAMPs) are essential for pollen tube growth. The Plant Journal 61:826-838.

10. Tse YC*, Lam SK, Jiang L. (2009) Organelle identification and characterization in plant cells: Using a combinational approach of confocal immunofluorescence and electron microscope. Journal of Plant Biology 52:1-9.

11. Lam SK, Cai Y, Tse YC, Wang J, Law AH, Pimpl P, Chan HY, Xia J, Jiang L. (2009) BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells. The Plant Journal 60:865-881.

12. Lam SK, Tse YC, Miao Y, Li HY, Wang J, Lo SW, Jiang L. (2007) Molecular characterization of plant prevacuolar and endosomal compartments. Journal of Integrative Plant Biology 49:1119-1128.

13. Lam SK, Tse YC, Robinson DG and Jiang L. (2007) Tracking down the elusive early endosome. Trends in Plant Science 12: 497-505.

14. Tse YC*, Lam SK and Jiang L. (2007) Enigmatic Brefeldin A. Plant Signaling & Behavior. Plant Physiology 2: 199-202.

15. Tse YC*, Lo SW, Hillmer S, Dupree P and Jiang L. (2006) Dynamic response of prevacuolar compartments to Brefeldin A in plant cells. Plant Physiology 142:1442-1459.

16. Oliviusson P, Heinzerling L, Hillmer S, Hinz G, Tse YC, Jiang L and Robinson DG. (2006) Plant retromer: identification, localization to the prevacuolar compartment and microvesicles, and preliminary evidence for an interaction with vacuolar sorting receptors. Plant Cell 18:1239-1252.

17. Tse YC*, Mo BX* and Jiang L. (2006) Plant prevacuolar/endosomal compartments. International Review of Cytology 253:95-129. (* these authors contributed equally to this work.)

18. Fung KL, Yim YF, Tse YC, Miao Y, Sun SSM and Jiang L. (2005) Targeting and processing of membrane-anchored YFP fusion proteins to protein storage vacuole in transgenic tobacco seeds. Seed Science Research 15:361-364.

19. Lam SK, Tse YC, Jiang L, Oliviusson P, Heinzerling L and Robinson DG. (2005) Plant prevacuolar compartments and endocytosis. In “Plant Endocytosis” Samaj, J., Baluska, F. and Menzel, D. (eds) Plant Cell Monographs 1:37-61.

20. Tse YC*, Mo B, Zhao M, Robinson DG, Hillmer S, Lo SW and Jiang L. (2004) Identification of multivescular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. Plant Cell 16:672-693.

21. Jin JB, Bae H, Kim SJ, Jin YH, Goh CH, Kim DH, Lee YJ, Tse YC, Jiang L and Hwang I. (2003) The Arabidopsis dynamin-like proteins ADL1C and ADU1E play a critical role in mitochondrial morphogenesis. Plant Cell 15:2357-2369.

22. Mo B, Tse YC and Jiang L. (2003) Organelle identification and proteomics in plant cells. Trends in Biotechnology 21:331-332.

23. Li YB, Rogers SW, Tse YC, Lo SW, Sun SSM., Jauh GY and Jiang L. (2002) BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant & Cell Physiology 43:726-742.

24. Lee SM, Li ML, Tse YC, Leung SC, Lee MM, Tsui SK, Fung KP, Lee CY, Waye MM. (2002) Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. Life Science. 71:2267-2277.

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  • 南科大-香港理工大学联合学术研讨会在我校举行

    2019年11月2日,由我校研究生院主办的南科大-香港理工大学(下文简称“港理工”)联合学术研讨会在我校图书馆报告厅举行,研讨会旨在进一步促进两校在人才培养与科研创新领域的合作和交流。由港理工校长滕锦光率领的学术代表团一行约40人访问我校。我校副校长、总务长鲁春接待了客人。本次研讨会按学科领域设置了三个分会场,共吸引了两校近70名教授学者参加并做报告。南科大材料科学与工程系讲席教授项晓东,南科大计算机科学与工程系讲席教授杨双华,南科大机械与能源工程系讲席教授张璧,香港理工大学纺织及制衣学讲席教授陶肖明,香港理工大学电子与资讯工程系主任、国际电子电机工程学会(IEEE)会士蔡定平,香港理工大学建筑与房地产学系主任、讲席教授李恒,香港理工大学屋宇设备工程学系讲席教授牛建磊,香港理工大学土木及环境工程系讲席教授殷建华等分别作报告,介绍了其研究领域、研究成果,以及指导研究生的经验等。开幕式上,滕锦光表示,此次以港理工校长的身份再度“回”到南科大,感到非常高兴。希望两校结合各自办学的优势,进一步深化学术科研、人才培养等方面的交流与合作,推动双方进一步的高质量发展。鲁春代表我校对港理工代表团的来访表示欢迎,并表示,希望双方积极探索合作机会,以更深层次、更广泛的合作推动形成更优秀的科研成果、培养出更多的拔尖创新人才,服务粤港澳大湾区的建设发展。 学术交流会后,港理工代表团前往我校创新创业学院、机械与能源工程系、材料科学与工程系、环境科学与工程学院、地球与空间科学系参观,作进一步交流。 我校目前与香港地区的五所知名高校开展了博士联合培养项目,包括香港大学、香港科技大学、香港浸会大学、香港理工大学与香港城市大学。今年9月,我校迎来了与港理工联合培养的第一批博士生。

    2019-11-05

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Introduction

 

Welcome to the Department of Biology! Since its establishment in 2012, the Department of Biology has attracted internationally renowned professors to join as leaders and dozens of young scientists to start their independent academic career here pursuit of excellence in research and teaching. The research interests of our faculty members include diverse topics such as systems biology, plant biology, neurobiology, structural biology and molecular cell biology. The primary goals of our faculty are to address the most significant fundamental biological questions and to develop new strategies to treat various complex diseases. Such efforts will benefit from the shared inter-disciplinary collaborative spirit deeply rooted in the minds of all the faculty members working in different departments at SUSTech.

 

Mentoring the next generation biologists with the highest standards is another primary task of the Department of Biology. Our professors choose internationally acclaimed textbooks to teach core courses biological sciences, biotechnology and bioinformatics. Undergraduates are encouraged to join the laboratory early to get firsthand working experience in basic and/or applied biological research, which helps them to consolidate the mastering of basic techniques, to broaden their knowledge horizons and to acquire the capabilities of problem identifying, hypothesis formulating and problem solving.

 

Life science, one of the fastest developing natural scientific disciplines, has been the driving force behind the growth of the world economy and provides the know for the development of new technologies serving to improve the human health and welfare at large. Wit generous financial support from the Shenzhen municipal government, we are confident that the Department of Biology in SUSTech will surely grow into a top tier globally-renowned research and teaching center!

 

Undergraduate Major:
Biological Sciences
Biotechnology
Bioinformatics

 

Master & PhD degree program:
Biology

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Contact Address

NO.1 Faculty Research Building

Office Phone

0755-88018409

Email

tseyc@sustc.edu.cn

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