Associate Professor Department of Chemistry

Dr. Ruijun Tian obtained his Ph.D. in analytical chemistry from Dalian Institute of Chemical Physics, Chinese Academy of Sciences in 2008 (Mentor: Dr. Hanfa Zou). He then moved to Canada for his postdoctoral training with Dr. Daniel Figeys at Ottawa Institute of Systems Biology, University of Ottawa (2008-2010) and Dr. Tony Pawson at Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and University of Toronto (2010-2014). In 2014, he joined Department of Chemistry, Southern University of Science and Technology (SUSTech) as an associate professor. He is also adjunct professor of School of Medicine, University of Ottawa and Shenzhen People’s hospital. His major research interest is precision medicine-oriented MS-based proteomics technology development and applications mainly in intercellular signaling of tumor microenvironment. He has published more than 50 research papers in Nature, PNAS, Angew Chem., Mol. Cell. Proteomics, Anal. Chem., etc. with H-index of 25 (Google Scholar). He received 2012 Young Investigator Award from International Association for Protein Structure Analysis and Proteomics (IAPSAP), Canadian Institutes of Health Research (CIHR) postdoctoral fellowship, and President’s Scholarship from Chinese Academy of Sciences. He was the co-chairs for 2nd Young Investigator Symposium of CNHUPO and 5th China-Canada Systems Biology Symposium. He is the editorial board member for Frontiers in Endocrinolog and Austin Proteomics.

Personal Profile


1. MS-based proteomics method and technology development

2. Chemical proteomics-based dynamic protein complex analysis

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1. MS-based proteomics method and technology development

(1) Ruilian Xu*, Jun Tang*, Quantong Deng, Wan He, Xiujie Sun, Ligang Xia, Zhiqiang Cheng, Lisheng He, Shuyuan You, Jintao Hu, Yuxiang Fu, Jian Zhu, Yixin Chen, Weina Gao, An He, Zhengyu Guo, Lin Lin, Hua Li, Chaofeng Hu, and Ruijun Tian‡, Spatial-Resolution Cell Type Proteome Profiling of Cancer Tissue by Fully Integrated Proteomics Technology, Anal. Chem. 2018, 90, 5879−5886

(2) Xu Zhang*, Wendong Chen*, Zhibin Ning, Janice Mayne, David R. Mack, Alain Stintzi‡, Ruijun Tian‡, and Daniel Figeys‡, Deep Metaproteomics Approach for the Study of Human Microbiomes, Anal. Chem., 2017, 89, 9407-9415

(3) Wendong Chen, Shuai Wang, Subash Adhikari, Zuhui Deng, Lingjue Wang, Lan Chen, Mi Ke, Pengyuan Yang, Ruijun Tian‡, Simple and Integrated Spintip-based Technology Applied for Deep Proteome Profiling, Anal. Chem., 2016, 88, 4864-4871

2. Chemical proteomics-based dynamic protein complex analysis

(1) Yu Shi‡, Weina Gao, Nikki K. Lytle, Peiwu Huang, Xiao Yuan, Amanda M. Dann, Maya Ridinger, Kathleen E. DelGiorno, Galina Erikson, Huaiyu Sun, Jill Meisenhelder, Elena Terenziani, Puifai Santisakultarm, Uri Manor, Ruilian Xu, Mathias Leblanc, Sarah E. Umetsu, Eric A. Collisson, Andrew M. Lowy, Tannishtha Reya, Timothy R. Donahue, Michael Downes, Geoffrey M. Wahl, Ronald M. Evans, Tony Pawson, Ruijun Tian‡, Tony Hunter‡, Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring, Nature, 2019, 569, 131-135

(2) Bizhu Chu*, An He*, Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Ruilian Xu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Shawn S. C. Li, Ying Sun‡, Pengfei Li‡, Tony Hunter, Ruijun Tian‡. Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc. Natl. Acad. Sci. U. S. A., 2018, 115, E8863-E8872

(3) Ruijun Tian*‡, Haopeng Wang*, Gerald D. Gish, Evangelia Petsalaki, Adrian Pasculescu, Yu Shi, Marianne Mollenauer, Richard D. Bagshaw, Nir Yosef, Tony Hunter, Anne-Claude Gingras, Arthur Weiss‡, Tony Pawson, A combinatorial proteomic analysis of intercellular signaling applied to the CD28 T cell co-stimulatory receptor, Proc. Natl. Acad. Sci. U. S. A., 2015, 112, E1594–E1603

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  • 2019-10-14: SUSTech hosted International Frontier Forum on Chemical Biology and Omics Research

    Earlier this week, Southern University of Science and Technology (SUSTech) was the host venue of the Frontier Forum on Chemical Biology and Omics Research (International Forum). The Department of Chemistry was a major sponsor of this International Forum, which saw over 100 experts and scholars from across the Greater Bay Area descend upon our campus.   The […]

  • 2019-04-18: SUSTech scientists collaborate on new pancreatic cancer treatment targets

    Pancreatic cancer is thought to be the “king of cancers,” in that it has no obvious symptoms in its earliest stages, and is often only diagnosed after the tumor has metastasized and spread throughout the entire body. It often responds badly to chemotherapy as the tumor cells are usually located with the dense stroma, or […]


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