长聘副教授(研究员) |生命科学学院, 系统生物学系
南方科技大学生命科学学院长聘副教授,研究员,博士生导师。深圳市海外高层次人才,南方科技大学动物中心副主任 。主持国家自然科学基金面上基金/青年基金、广东省、深圳市多项基础研究项目,作为核心骨干参与国自然重点基金、广东省重点实验室等项目 。相关研究成果在《 Nature Communications》、《PNAS》、《JASN》、《JCB》 《Oncogene》等国际一流杂志上 发表论文多篇。
个人简介
研究领域
1.肾脏疾病分子机理的研究
2.肿瘤细胞-微环境互作对肿瘤演进的研究
3.腺苷在炎症反应中的作用及其分子机制
教学
1.人类健康与疾病概述
2.微生物学
3.微生物学实验
4.生命科学前沿讲座
学术成果 查看更多
近五年,孙颖教授发表SCI论文十余篇,主持并参与国家重大项目,面上项目,青年项目等,取得丰硕学术成果。
Corresponding author (*) Publications
- Yang A, Ding Y, Guo C, Liu C, Xiong Z, Quan M, Bai P, Cai R, Li B, Li G, Deng Y, Wu C, Sun Y*. (2024) PARVB deficiency alleviates cisplatin-induced tubular injury by inhibiting TAK1 signaling. Cell Mol Life Sci. 1007/s00018-024-05422-w
- Cai R, Bai P, Quan M, Ding Y, Wei W, Liu C, Yang A, Xiong Z, Li G, Li B, Deng Y, Tian R, Zhao Y, Wu C*, Sun Y*. (2024) Migfilin promotes autophagic flux through direct interaction with SNAP29 and Vamp8. Journal of Cell Biology. 2024 10.1083/jcb.202312119
- Liu C, Jiang K, Ding Y, Yang A, Cai R, Bai P, Xiong M, Fu C, Quan M, Xiong Z, Deng Y, Tian R, Wu C*, Sun Y*. (2023). Kindlin-2 enhances c-Myc translation through association with DDX3X to promote pancreatic ductal adenocarcinoma progression. Theranostics. doi:10.7150/thno.85421; accepted
- Guo C#, Ding Y#, Yang A, Geng Y, Liu C, Zhou L, Ma L, Yang Z, Hu Feng, Jiang K, Cai R, Bai P, Quan M, Deng Y, Wu C*, Sun Y*. (2022). CHILKBP protects against podocyte injury by preserving ZO-1 expression. Cell. Mol. Life Sci. Dec. 24; 80(1):18.
- Ma L #, Tian Y #, Qian T, Li W, Liu C, Chu B, Kong Q, Cai R, Bai P, Ma L, Deng Y, Tian R, Wu C*, Sun Y*. (2022). Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression. Cell Death & Disease. 13:482
- Y Xu#, C Guo#, W Pan#, C Zhao , Y Ding , X Xie , Z Wei*, Y Sun*, C Yu*. (2021). Nephrotic syndrome-assoicated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J Biol. Chem. 16, July
- Liu J#, Liu Z#, Chen K#, Chen W, Fang X, Li M, Zhou X, Ding N, Lei H, Guo C, Qian T, Wang Y, Liu L, Chen Y, Zhao H, Sun Y*, Deng Y*, Wu C*. (2021). Kindlin-2 promotes rear focal adhesion disassembly and directional persistence in cell migration. J Cell Sci. Jan 13;134(1)
- Qian T#, Liu C#, Ding Y, Guo C, Cai R, Wang X, Wang R, Zhang K, Zhou L, Deng Y, Wu C*, Sun Y*. (2020). PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis. Oncogene. Mar;39(10):2069-2087
- Sun Y*#, Ding Y#, Guo C#, Liu C, Ma P, Ma S, Wang Z, Liu J, Qian T, Ma L, Deng Y, Wu C*. (2019). α-parvin promotes breast cancer progression and metastasis through interaction with G3BP2 and regulation of TWIST1 signaling. Oncogene. Jun;38 (24):4856-4874.
- Guo L*, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y*, Wu C*. (2019). Kindlin-2 links mechano-environment to proline synthesis and tumor growth. Nat Commun. 10(1):845.
- Chu B#, He A#, Tian Y, He W, Chen P, Hu J, Xu R, Zhou W, Zhang M, Yang P, Sun Y*, Li P*, Hunter T, Tian R*. (2018). Photoaffinity engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc Natl Acad Sci U S A. 115(38):E8863-E8872.
- Sun Y*#, Guo C#, Ma P, Lai Y, Yang F, Cai J, Sheng Y, Cheng Z, Tian R, Deng Y, Xiao G*, Wu C*. (2017). Kindlin-2 association with Rho GDP-Dissociation Inhibitor α suppresses Rac1 activation and podocyte injury. J Am Soc Nephrol. 28 (12): 3545-3562.
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南方科技大学
学苑大道 1088, 深圳, 518055, 中国
E-mail: suny@sustech.edu.cn; Tel(O): +86-755-88018412