Associate Professor School of Medicine

Quan Liu, M.D., Ph.D., is an associate professor in the School of Medicine at SUSTech as well as a junior attending surgeon. Dr. Liu achieved his Medical Degree from Harbin Medical University (HMU) in 2002. He received his surgical training at the Second Affiliated Hospital of HMU from late 2002 through 2008 and specialized in cardiothoracic surgery. Dr. Liu moved forward for his Ph.D. degree and spent over 8 years (from 2009 to 2017) at the University of Pittsburgh. He studied transplantation immunobiology, inflammation regulation, and immunobiology of IL-33 and regulatory T cells (Treg) in the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh with Drs. Heth Turnquist and Adrian Morelli. The main findings of Dr. Liu’s work include: 1, The direct pathway of alloantigen presentation is not sufficient for acute allograft rejection. 2, Exosomes from donor dendritic cells are key for indirect pathway of alloantigen presentation. 3, Recipient antigen presenting cells are key for the maintenance of allorejection. 4, Treg cells and IL-33 regulate tissue repair during acute lung injury (ALI) and are indispensable for mouse survival after ALI induced by intratracheal bleomycin injection. Dr. Liu has published 15 papers included by Scientific Index Citation (SCI), 5 of which were published in high-impact journals (IF > 10) including Journal of Clinical Investigation (JCI), Nature Communications and Blood. The paper published in JCI has been categorized as a highly-cited paper by the SCI database shortly after publication. Dr. Liu has completed a grant from National Nature Science Foundation, China. He won Provincial Awards of Science and Technology Progress in 2007 and 2008 in China, and Young Investigator Award at the 2013 American Transplant Congress in the United States. Dr. Liu was selected for a Distinguished Young Talents project of the Second Affiliated Hospital of HMU in 2017.

Personal Profile

Research

1. Alloantigen presentation

2. Immunobiology of IL-33, Treg and ILC2 in settings of transplantation, inflammation regulation, tumor and immunotherapy


Teaching

Immunology, Biochemistry, Surgery, Physiology and Pathophysiology


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The scientific contribution of Dr. Liu includes:1, Elucidated for the first time that the donor dendritic cell-derived exosomes is the material basis for mediating the semi-direct pathway of alloantigen presentation. 2, Revealed the role of intra-allograft recipient-derived dendritic cells in maintaining transplant rejection. 3, Investigated the role of IL-33 in tissue protection during acute lung injury and heart transplant rejection. Dr. Liu has published 16 scientific papers,five of which were published in JCI, Nature Communications and Blood. The paper published in JCI is highly cited according to the data from Web of Science. Dr. Liu has successfully completed a Young Scientist Program from the National Natural Science Foundation (NSFC) of China. A General Program from NSFC was awarded to Dr. Liu in 2019. Dr. Liu won Young Investigator Award at the American Transplant Congress, and provincial scientific awards twice in China.

Lab members Read More

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Contact Us

Contact Address

Room 506, Southern University of Science and Technology,1088 Xueyuan Blvd, Nanshan District, Shenzhen, Guangdong,China

Office Phone

0755-88018055

Email

liuq3@sustc.edu.cn

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