Assistant Professor Department of Biomedical Engineering

Chao Liu is an Assistant Professor at Southern University of Science and Technology (2019-present). Chao received his Bachelor of Applied Science in Engineering Science from University of Toronto (2008), in Canada. He received his Master of Applied Science in Mechanical Engineering (2010) and PhD in Biomedical Engineering at the Institute of Biomaterials and Biomedical Engineering, University of Toronto (2016). Chao has completed a postdoctoral fellowship at New York University with joint appointment from the Department of Biomedical Engineering and Department of Orthopedics at NYU Langone Health medical center. Chao’s research interests include the mechanobiology of bone cells and stem cells, and tissue engineering of bone tissue for regenerative medicine applications of enhancing bone repair.

Education:

2010-2016 PhD, Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto, Canada

2008-2010 MASc, Mechanical Engineering, University of Toronto, Canada

2003-2008 BASc, Engineering Science - Biomedical Engineering, University of Toronto, Canada

Work Experience: 

2019-present, Assistant Professor, Department of Biomedical Engineering, Southern University of Science and Technology

2016-2019, Post-doctoral Fellow, Department of Biomedical Engineering, Langone Medical Center, New York University

Honors and Awards:

2017 International Federation of Musculoskeletal Research Societies Travel Grant

2016 American Society of Bone and Mineral Research Young Investigator Travel Grant

2010-2014 Canadian Institutes of Health Research Travel Awards

2011-2013 Ontario Graduate Scholarship

2008, 2010 Barbara and Frank Milligan Graduate Fellowship

Personal Profile

Biosketch:
Chao Liu is an Assistant Professor at Southern University of Science and Technology (2019-present). Chao received his Bachelor of Applied Science in Engineering Science from University of Toronto (2008), in Canada. He received his Master of Applied Science in Mechanical Engineering (2010) and PhD in Biomedical Engineering at the Institute of Biomaterials and Biomedical Engineering, University of Toronto (2016). Chao has completed a postdoctoral fellowship at New York University with joint appointment from the Department of Biomedical Engineering and Department of Orthopedics at NYU Langone Health medical center. Chao’s research interests include the mechanobiology of bone cells and stem cells, and tissue engineering of bone tissue for regenerative medicine applications of enhancing bone repair.

Education:
2010-2016 PhD, Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto, Canada
2008-2010 MASc, Mechanical Engineering, University of Toronto, Canada
2003-2008 BASc, Engineering Science - Biomedical Engineering, University of Toronto, Canada

Work Experience: 
2019-present, Assistant Professor, Department of Biomedical Engineering, Southern University of Science and Technology
2016-2019, Post-doctoral Fellow, Department of Biomedical Engineering, Langone Medical Center, New York University

Honors and Awards:
2017 International Federation of Musculoskeletal Research Societies Travel Grant
2016 American Society of Bone and Mineral Research Young Investigator Travel Grant
2010-2014 Canadian Institutes of Health Research Travel Awards
2011-2013 Ontario Graduate Scholarship
2008, 2010 Barbara and Frank Milligan Graduate Fellowship

Research Interests:

1.Utilize mechanical forces to alter bone forming (osteogenic) and blood vessel forming (angiogenic) stem cells that ultimately enhance bone regeneration.
2.Develop bone-interfacing implants with functional micro-geometry to enhance the activity of angiogenic and osteogenic stem cells.
3. Develop 3D real-time cellular and molecular imaging modalities to observe the bone repair process in situ.

Selected Publications:

1. Chao Liu, Pamela Cabahug‐Zuckerman, Christopher Stubbs, Martin Pendola, Cinyee Cai, Kenneth A. Mann, and Alesha B. Castillo. "Mechanical loading promotes the expansion of primitive osteoprogenitors and organizes matrix and vascular morphology in long bone defects." Journal of Bone and Mineral Research (2019).
2. Ma, Yu-Heng Vivian; Lam, Candy; Dalmia, Shreyash ; Gao, Peter; Young, Jacob; Middleton, Kevin; Liu, Chao; You, Lidan. “Mechanical regulation of breast cancer bone metastasis via direct and indirect osteocyte signalling in vitro” Journal of Cellular Biochemistry. 2018, Accepted.
3. Chao Liu, Robert Carrera, Vittoria Flamini, Lena Kenny, Pamela Cabahug-Zuckerman, Benson George, Daniel Hunter, Bo Liu, Gurpreet Singh, Philipp Leucht, Kenneth A Mann, Jill A Helms, Alesha B Castillo, “Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing” Bone. 2018, 108, pp. 145-155.
4. Qian, Weiyi; Gong, Lanqi; Cui, Xin; Zhang, Zijing; Bajpai, Apratim; Liu, Chao; Castillo, Alesha; Teo, Jeremy; Chen, Weiqiang “Nanotopographic regulation of human mesenchymal stem cell osteogenesis” ACS Applied Materials & Interfaces. 2017, 9 (48), pp 41794–41806.
5. Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P. “The selective serotonin re-uptake inhibitor fluoxetine directly inhibits osteoblast differentiation and mineralization during fracture healing in mice.” Journal of Bone and Mineral Research. 32(4) 2017: 821–833.
6. Chao Liu, Xin Cui, Thomas Michael Ackermann, Vittoria Flamini, Weiqiang Chen, Alesha Castillo “Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation” Integrative Biology 8(7) 2016, 785-794.
7. Chao Liu, Xiaoqing Zhang, Michael Wu, Lidan You “Mechanical Regulation of Osteocyte Responses to Physical Damage in vitro” Journal of Biomechanics 2015. 48(16): 4221-4228.
8. Ashutosh Parajuli*, Chao Liu*, Wen Li*, Xiaoyu Gu, Xiaohan Lai, Christopher Price, Lidan You, X. Lucas Lu, Liyun Wang “Bone's Responses to Mechanical Loading are Impaired in Type 1 Diabetes” Bone 81 (2015) 152–160. (*Equal contributions).
9. Jia-Ning Zhang, Yan Zhao, Chao Liu, Elizabeth S. Han, Xue Yu, Darcy Lidington, Steffen-Sebastian Bolz, Lidan You “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction Bone” Bone 79 (2015) 71-78. 
10. Chao Wei, Beiyuan Fan, Deyong Chen, Chao Liu, Yuanchen Wei, Bo Huo, Lidan You, Junbo Wang and Jian Chen “Osteocyte Culture in Microfluidic Devices” Biomicrofluidics. 9, 014109 (2015).
11. Wing-Yee Cheung, Chao Liu, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30.
12. Chao Liu, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. 46 (5), May 2010, pp. 1449-1456.
13. Chao Liu, Alesha B. Castillo, “Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair” Journal of the American Academy of Orthopaedic Surgeons. 2018 (invited review).
14. Jan-Hung Chen*, Chao Liu*, Lidan You, Craig A. Simmons, “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (1), pp. 108-118 (*Equal contributions) (invited review).

Research

Chao received his Bachelor of Applied Science in Engineering Science from University of Toronto (2008), in Canada. He received his Master of Applied Science in Mechanical Engineering (2010) and PhD in Biomedical Engineering at the Institute of Biomaterials and Biomedical Engineering, University of Toronto (2016). Chao has completed a postdoctoral fellowship at New York University with joint appointment from the Department of Biomedical Engineering and Department of Orthopedics at NYU Langone Health Medical Center. Chao’s research interests include the mechanobiology of bone cells and stem cells, tissue engineering of bone tissue for regenerative medicine applications, and functional bone-interfacing implants.


Teaching

Introduction to Biomedical Engineering II (Biomechanics II)

Biomedical Engineering I: Biomechanics


Publications Read More

Professor Chao Liu has published 14 journal articles, with 550 citations (Google Scholar). In the last three years, Chao has presented in 6 international conferences.

News More

  • Professor Liu Chao visited The General Hospital of the People's Liberation Army (PLAGH)

          Prof. Liu Chao and Prof. Li Kai visited Prof. Gu Ying at The General Hospital of the People's Liberation Army (PLAGH) on August 17. Academician Gu Ying is an adjunct professor of our department, an academician of Chinese academy of sciences, and chief physician of laser medicine department of The General Hospital of the […]

    2019-09-05
  • Professor Liu Chao attended The 17th China And International Biophysics Conference and gave an oral presentation

        The 17th China-International Biophysics Bonference Hosted by the Chinese biophysics society was held in Tian Jin from August 2-5, 2019.The President of the conference is academician Xu Tao, President of the Chinese society of biophysics. With the theme of "Biophysics And Human Health", this conference, centering on the latest research progress and development trend […]

    2019-09-05

Lab members Read More

Join us

Postdoctoral recruitment

(1)Qualifications:

1、A Ph.D. in related disciplines in biology or engineering has been obtained or will be obtained in the near future.

2、Background with image analysis, mechanical testing, cell experiments, or small animal models is preferred.

3、Responsible, hands-on, diligent, team-oriented, and independent research capabilities.

4、SCI papers have been published in related fields, and publications in international peer-reviewed journals are preferred. 5、Good ability of literature review and English writing.

(2)Research direction:

1、Utilize mechanical forces to alter bone forming (osteogenic) and blood vessel forming (angiogenic) stem cells that ultimately enhance bone regeneration

2、Develop bone-interfacing implants with functional micro-geometry to enhance the activity of angiogenic and osteogenic stem cells

3、 Develop 3D real-time cellular and molecular imaging modalities to observe the bone repair process in situ.

 

(3)Treatment:

1、Advanced research facilities and world-class research.

2、The annual salary is RMB 320,000, including the living allowance of RMB 180,000/year (tax exempt). In addition, the research team provides additional allowances and rewards for outstanding postdocs. Special outstanding candidates can apply for the Principal's outstanding postdoctoral award, with an annual salary of more than 360,000 yuan;

3、Enjoy housing subsidies and social insurance such as medical care, old-age care, and work-related injuries; enjoy benefits such as savings, meal supplements, family planning rewards, high-temperature subsidies, and free medical examinations.

4、Provide 50,000 yuan every two years for each post-doctoral fellowship for academic exchanges (including international conferences);

5、Assist in applying for the National Natural Science Foundation, the corresponding basic research and professional innovation projects in Guangdong Province and Shenzhen, and support the application of various research funds as project leaders.

6、Those who meet the requirements can apply for the Shenzhen Peacock Project or Shenzhen high-level talents, provide 1.6 to 2 million housing subsidies, and 2 to 5 million scientific research start-up funds.

7、Assist in applying for the National Natural Science Foundation, the corresponding basic research and professional innovation projects in Guangdong Province and Shenzhen City;

8、Shenzhen has a large enterprise group, R&D institutions and research institutes, and has many job opportunities. Those who have outstanding performance after leaving the station can give priority to recommending the work of Southern University of Science and Technology or other units or recommending to foreign cooperation units to continue to communicate;

 

Research assistant position

(1)Application conditions:

1、Excellent undergraduate or postgraduate graduates in related fields such as biology or engineering.

2、Candidates who wish to pursue a doctoral degree are preferred, and those who have published an SCI paper are preferred.

3、Serious and responsible working attitude, strong hands-on ability, diligent and hard-working, proactive, team-oriented, and solid experimental skills.

4、Good English reading and writing skills。

(2)Treatment:

The initial monthly salary is 5000-8000 RMB, which can be adjusted based on academic qualifications, personal ability and experience; enjoy the festival and monthly meal benefits; enjoy basic pension insurance, basic medical insurance, unemployment insurance, work injury insurance, maternity insurance, housing provident fund, etc.

Those who perform well can apply for the graduate program of the University of South University and foreign (outside) universities to cooperate in the development of postgraduate programs or the cooperation between the South University of Science and the domestic (domestic) first-class universities, and have the opportunity to be recommended to visit the world's leading universities.

Those who perform well can apply for the graduate program of the University of South University and foreign (outside the mainland) universities to cooperate in the development of postgraduate programs or the cooperation between the South University of Science and the domestic (within the mainland) first-class universities, and have the opportunity to be recommended to visit the world's leading universities.

 

PhD, master student

With professional backgrounds in biology, biomedical engineering, mechanical engineering, computer engineering, etc.. Students loves scientific research, has strong curiosity, and is diligent in work or has published SCI papers will be considered first. Opportunity to apply for joint training programs with universities such as the National University of Singapore, the Hong Kong University of Science and Technology, the University of Macau, and the University of Leeds, UK. Southern University of Science and Technology will provide scholarships for the selected students, with a master's degree of 50,000 RMB/year and a PhD of approximately 100,000 RMB/year (The overseas joint training project is funded according to the overseas scholarship amount and awarded the degree of the overseas university). Those who are extremely out-standing will have the opportunity to be recommended to exchange at a top foreign university. 

 

Contact information

Please send the application materials to:liuc33@sustech.edu.cn,Please indicate the subject of the email like "XXX apply for postdoctoral; XXX apply for research assistant"。 Applicants will be carefully considered and arranged for an interview in time, and personal information will be strictly protected.

 

Read More

Contact Us

Contact Address

No 1088, Xueyuan Road, Nanshan District, Shenzhen, Guangdong, China

Office Phone

0755-88015292

Email

liuc33@sustech.edu.cn

Copyright © 2018 All Rights Reserved.