助理研究教授 前沿与交叉科学研究院

罗启邦博士是专门研究生物和临床质谱学的高级研究员,在代谢组学/脂质组学和蛋白质组学以及相关信息学方面拥有广泛的知识和技能。罗博士于2008年在英国诺丁汉大学药学院获得博士学位。此后,他在英国华威大学临床科学研究所, 英国格林威治大学科学学院, 以及新加坡国立大学永罗林医学院担任博士后研究员。在加入SUSTech之前,罗博士是重庆医科大学质谱中心的高级实验师, 引领该中心的发展。罗博士作为第一作者和主要作者发表了大量文章。他最重要的工作包括开发基于纳米结构表面的表面辅助激光解吸/电化技术,研究定量蛋白质组学的数据独立采集方法以及妊娠期糖尿病的病理生理学。罗博士目前正在实施一种离子渡度质谱方案,用于全面分析海洋系统中的微生物, 如古菌脂质和外代谢组,研究其与环境因素变化相关的生理变化,以及这些因子的生态作用。

个人简介

研究领域

1. 离子渡度质谱法

2. 脂质组学

3. 代谢组学

4. 多变量统计

5. 化学信息学


学术成果 查看更多

• Kai P. Law* and Chuanlun L. Zhang. Current Progress and Future Trends of Mass Spectrometry-based Archaeal Lipidomics. Organic Geochemistry, 134 (2019) 45–61.

• Xun Mao, Xuyang Chen, Chang Chena, Hua Zhang, Kai P. Law*. Metabolomics in gestational diabetes. Clinica Chimica Acta, 475 (2017) 116–127.

• Ting-Li Han, Ying Yang, Hua Zhang, Kai P. Law*. Analytical Challenges of Untargeted GC-MS-based Metabolomics and the Critical Issues in Selecting the Data Processing Strategy. F1000Research 2017, 6:967.

• Kai P. Law* and Hua Zhang. The Pathogenesis and Pathophysiology of Gestational Diabetes Mellitus: Deductions from a Three-part Longitudinal Metabolomics Study in China. Clinica Chimica Acta, 468 (2017) 60–70.

• Kai P. Law*, Ting-Li Han, Xun Mao, and Hua Zhang. Tryptophan and Purine Metabolites are consistently upregulated in the Urinary Metabolome of Patients Diagnosed with Gestational Diabetes Mellitus throughout Pregnancy: A Longitudinal Metabolomics Study of Chinese Pregnant Women Part 2. Clinica Chimica Acta, 468 (2017) 126–139.

• Kai P. Law*, Xun Mao, Ting-Li Han, and Hua Zhang. Unsaturated Plasma Phospholipids are consistently lower in the Patients Diagnosed with Gestational Diabetes Mellitus throughout the Gestation: A Longitudinal Metabolomics Study of Chinese Pregnant Women Part 1. Clinica Chimica Acta. 465 (2017) 53–71.

• Yue Wang, Linqiang Ma, Xiaoyu Shu, Jiayu Li, Jinbo Hu, Kai P. Law, Ting Luo, Richa Goswami, Shumin Yang, Suhua Zhang, and Qifu Li. Apparent mineralocorticoid excess caused by a novel mutation in 11-hydroxysteroid dehydrogenase type 2 gene. Journal of Hypertension, 35 (3), 647-650 (2017).

• Aihua Hou, Kai Pong Law, Min Qi Tin, and Louis Tong. In vitro Secretomics study of Pterygium-derived Fibroblasts by iTRAQ-based Quantitative Proteomics Strategy. Experimental Eye Research. 153, 14–22 (2016). Equally contributed author.

• Kai P. Law*, and Ting-Li Han. The Importance of Suitable GC-MS Date Processing and Analysis for Environmental Metabolomics. Environmental Science and Pollution Research 23 (10) 0276-10285, (2016).

• Kai P. Law*, Ting-Li Han, Philip N. Baker. Mass Spectrometry-based Proteomics for Pre-eclampsia and Preterm Birth. International Journal of Molecular Sciences 16 (5), 10952­10985 (2015)

• P. V. Iyengar, P. Jaynes, L. Rodon, D. Lama, Kai P. Law, C. Verma, J. Seoane & P. J. A. Eichhorn. USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination. Nature, Scientific Reports, 5, 14755 (2015).

• A. Hou, W. Lan, Kai P. Law, SCJ Khoo, M.Q. Tin, L. Tong. Evaluation of Global Differential Gene and Protein Expression in Primary Pterygium: S100A8 and S100A9 as Possible Drivers of a Signaling Network. PLoS ONE 9(5): e97402 (2014).

• Kai P. Law*. Recent Advances in Mass Spectrometry: Data Independent Analysis and Hyper Reaction Monitoring. Expert Review of Proteomics 10 (2013) 551-566.

• K.P. Law* and James R. Larkin. Recent Advances in SALDI-MS Techniques and Their Chemical and Bioanalytical Applications. Analytical and Bioanalytical Chemistry 399 (2011) 8 2597-2622.

• K.P. Law*. Laser Desorption/Ionization Mass Spectrometry on Nanostructured Semiconductor Substrates: DIOS™ and QuickMass™. International Journal of Mass Spectrometry 290 (2010) 72-84.

• K.P. Law*. Surface-Assisted Laser Desorption/Ionization Mass Spectrometry on Nanostructured Silicon Substrates Prepared by Iodine-assisted Etching. International Journal of Mass Spectrometry 290 (2010) 47-59.

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