讲席教授 生物系

郭红卫教授是教育部特聘教授、国家杰出青年基金获得者、科技部中青年科技创新领军人才、广东省“珠江人才”科技创新领军人才、深圳市海外高层次A类人才。现任南方科技大学生物系讲座教授,生物系副主任,南方科技大学-北京大学植物与食品联合研究所所长。郭红卫教授主要从事植物激素乙烯的作用机理、叶片衰老和果实发育的调控机制、RNA降解和基因沉默等方面的研究,取得了一系列开创性的研究成果,在这些领域处于国际领先地位。已在Cell 、Science、Nature、PNAS、 Plant Cell等国际刊物发表论文80余篇,授权发明专利8项。现为中国植物学会和中国作物学会常务理事,第十一届全国青联常委,并担任Plant Cell, Molecular Plant, Plant Cell and Physiology, JIPB等期刊编委。

个人简介

郭红卫教授,2001年博士毕业于美国加州大学洛杉矶分校,攻读博士学位期间曾以第一作者发表包括两篇Science在内的一系列研究论文,在植物光形态建成、光周期开花、光信号转导等对农业生产至关重要的领域取得了突破性进展,引起国际学术界广泛关注和反响;博士毕业后进入世界顶尖生物学研究所SALK开展博后研究工作,在植物激素的调控机理方面取得了重大突破,建立了乙烯通路的蛋白降解模型和RNA降解模型,分别发表在国际权威杂志CellPNAS上;2005年全职回国后,任北京大学生命科学学院教授、博士生导师,筹建了植物激素信号转导实验室。其实验室长期从事植物分子生物学及遗传学方面的研究,在植物激素生物学领域具有重要的国际影响力。近年来,郭红卫教授团队聚焦植物对异源或过量表达的基因多层次沉默的机制研究,以拟南芥为材料对植物中外源转基因沉默现象进行了研究,发现了植物防止内源基因沉默的双保险机制,相关成果发表在国际权威杂志Science上,并受著名生物学综述性期刊Current Opinion in Plant Biology特邀,总结近年来植物信使RNA (mRNA)代谢和mRNA质量监控研究领域的最新进展。此外,郭红卫教授团队长期关注植物器官衰老、果实发育调控机制等与生产实践密切相关的科学问题,综合利用化学遗传学等手段,筛选出多种受到同行认可的、具有潜在采后应用价值的小分子化合物。2016年起,任南方科技大学生物系讲座教授。2017年7月受南方科技大学委托筹建植物与食品联合研究所并担任首届研究所所长,2018年起任南方科技大学生物系副主任。

 

研究领域

植物激素信号转导

植物衰老与采后生物学

植物siRNA生物学

工作经历

2018.09-至今   南方科技大学生物系副主任

2017.07-至今  南科大-北大植物与食品联合研究所所长

2016.04-至今  南方科技大学生物系讲座教授

2013.09-2015.12   北京大学生命科学学院副院长

2005 .09– 2016.03   北京大学生命科学学院教授

2001.07 – 2005.09  美国加州Salk Institute 博士后

教育背景

1996 - 2001   美国加州大学洛杉矶分校(UCLA)   植物分子生物学专业  博士学位

1992 - 1995   北京大学生命科学学院 植物生理学专业   硕士学位

1988 - 1992   南开大学生物系 植物生理学专业  学士学位

获奖情况及荣誉

◆2018 广东省“珠江人才”科技创新领军人才

◆2018 国家高层次人才特殊支持计划领军人才

◆2018 深圳市海外高层次A类人才

◆2016 深圳市高层次人才国家级领军人才

◆2015 科技部中青年科技创新领军人才

◆2014 第七届“谈家桢生命科学创新奖”

◆2013 中国科协“科学中国人(2012)年度人物

◆2011 第十二届“中国青年科技奖”

◆2011  “北京大学-清华大学联合生命中心”首批研究员

◆2009 第十三届“中国青年五四奖章”称号

◆2008 中国植物学会“先进青年科技工作者”称号

◆2007 第二十二届北京市“五四奖章”标兵称号

◆2006 国家杰出青年科学基金

◆2006  教育部特聘教授

文章

2019:

  1. Huang Peixin , Dong Zhi , Guo Pengru , Zhang Xing , Qiu Yuping, Li Bosheng , Wang Yichuan and Guo Hongwei* (2019) Salicylic acid suppresses apical hook formation via NPR1-mediated repression of EIN3/EIL1 in Arabidopsis. Plant Cell, accepted.
  2. Zhu Ying, Li Hongjiang, Su Qi, Wen Jing, Wang Yuefan, Song Wen, Xie Yinpeng, He Wenrong, Yang Zhen, Jiang Kai*, and Guo Hongwei* (2019). A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis. Journal of Biological Chemistry,  in press.

2018:

  1. Wang Yichuan, and Guo Hongwei*(2018). Onhormonal regulation of the dynamic apical hook development. The New phytologist 222, 1230-1234.
  1. Li Bosheng, Wu Huihui, and Guo Hongwei*(2018). Plant mRNA decay: extended roles and potential determinants. Current Opinion in Plant Biology 45, 178-184.
  1. Wang Yichuan*, Ji Yusi, Fu Ying, and Guo Hongwei*(2018). Ethylene-induced microtubule reorientation is essential for fast inhibition of root elongation in Arabidopsis. Journal of Integrative Plant Biology 60, 864-877.
  2. Zhang Xing, Ji Yusi, Xue Chang, Ma Honghao, Xi Yulin, Huang Peixin, Wang Huan, An Fengying, Li Bosheng, Wang Yichuan, and Guo Hongwei*(2018). Integrated regulation of apical hook development by transcriptional coupling of EIN3/EIL1 and PIFs inArabidopsis. Plant Cell 30, 1971-1988.
  1. Zhang Cheng#, Teng Xiao-Dong#, Zheng Quan-Quan, Zhao Yan-Yun, Lu Jie-Yang, Wang Yichuan, Guo Hongwei*, and Yang Zhong-Nan*(2018). Ethylene signaling is critical for synergid cell functional specification and pollen tube attraction. Plant Journal 96, 176-187.
  1. Li Zhonghai, Woo Hye Ryun*, and Guo Hongwei*(2018). Genetic redundancy of senescence-associated transcription factors inArabidopsis. Journal of Experimental Botany 69, 811-823.

2017:

  1. Feng Ying, Xu Ping, Li Bosheng, Li Pengpeng, Wen Xing, An Fengying, Gong Yan, Xin Yi, Zhu Ziqiang, Wang Yichuan*, and Guo Hongwei*(2017). Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity inArabidopsis. Proceedings of the National Academy of Sciences of the United States of America 114, 13834-13839.
  1. Jiang Bochen, Shi Yiting, Zhang Xiaoyan, Xin Xiaoyun, Qi Lijuan, Guo Hongwei, Li Jigang, and Yang Shuhua*(2017). PIF3 is a negative regulator of the CBF pathway and freezing tolerance in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 114, E6695-E6702.
  1. Guo Pengru, Li Zhonghai, Huang Peixin, Li Bosheng, Fang Shuang, Chu Jinfang, and Guo Hongwei*(2017). A tripartite amplification loop involving the transcription factor WRKY75, salicylic acid, and reactive oxygen species accelerates leaf senescence. Plant Cell 29, 2854-2870.
  1. Zhang Xinyan, and Guo Hongwei*(2017). mRNA decay in plants: both quantity and quality matter. Current Opinion in Plant Biology 35, 138-144.
  1. Sun Xiangzhong, Li Yaxin, He Wenrong, Ji Chenggong, Xia Peixue, Wang Yichuan, Du Shuo, Li Hongjiang, Raikhel Natasha, Xiao Junyu*, and Guo Hongwei*(2017). Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase. Nature Communications 8,15758.

2016:

  1. Song Wen, Liu Li, Wang Jizong, Wu Zhen, Zhang Heqiao, Tang Jiao, Lin Guangzhong, Wang Yichuan, Wen Xing, Li Wenyang, Han Zhifu, Guo Hongwei*, and Chai Jijie*(2016). Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth. Cell Research 26, 674-685.
  1. Li Mingzhe, An Fengying, Li Wenyang, Ma Mengdi, Feng Ying, Zhang Xing, and Guo Hongwei*(2016). DELLA proteins interact with FLC to repress flowering transition. Journal of Integrative Plant Biology 58, 642-655.
  1. Zhang Xinyan, Zhu Ying, Wu Huihui, and Guo Hongwei*(2016). Post-transcriptional gene silencing in plants: a double-edged sword. Science China-Life Sciences 59, 271-276.
  1. Zhu Ziqiang, Xian Ziqiang, Guo Hongwei*, and Li Zhengguo*(2016). Ethylene biology blooms from fundamental research to postharvest applications. Molecular Plant 9, 187-188.
  1. Qing Dongjin, Yang Zhu, Li Mingzhe, Wong Wai Shing, Guo Guangyu, Liu Shichang, Guo Hongwei, and Li Ning*(2016). Quantitative and functional phosphoproteomic analysis reveals that ethylene regulates water transport via the C-terminal phosphorylation of aquaporin PIP2; 1 in Arabidopsis. Molecular Plant 9, 158-174.

2015:

  1. Li Wenyang, Ma Mengdi, Feng Ying, Li Hongjiang, Wang Yichuan, Ma Yutong, Li Mingzhe, An Fengying, and Guo Hongwei*(2015). EIN2-directed translational regulation of ethylene signaling in Arabidopsis. Cell 163, 670-683.
  1. Zhang Xinyan, Zhu Ying, Liu Xiaodan, Hong Xinyu, Xu Yang, Zhu Ping, Shen Yang, Wu Huihui, Ji Yusi, Wen Xing, Zhang Chen, Zhao Qiong, Wang Yichuan, Lu Jian, and Guo Hongwei*(2015). Suppression of endogenous gene silencing by bidirectional cytoplasmic RNA decay inArabidopsis. Science 348, 120-123.
  1. Song Jinghui, Zhu Chenxu, Zhang Xing, Wen Xing, Liu Lulu, Peng Jinying, Guo Hongwei*, and Yi Chengqi*(2015). Biochemical and structural insights into the mechanism of DNA recognition by ArabidopsisETHYLENE INSENSITIVE3. PLoS One 10, e0137439.

2014:

  1. Peng Jinying, Li Zhonghai, Wen Xing, Li Wenyang, Shi Hui, Yang Longshu, Zhu Huaiqiu, and Guo Hongwei*(2014). Salt-induced stabilization of EIN3/EIL1 confers salinity tolerance by deterring ROS accumulation in Arabidopsis. Plos Genetics 10, e1004664.
  1. Zhang Xing, Zhu Ziqiang, An Fengying, Hao Dongdong, Li Pengpeng, Song Jinghui, Yi Chengqi, and Guo Hongwei*(2014). Jasmonate-activated MYC2 represses ETHYLENE INSENSITIVE3 activity to antagonize ethylene-promoted apical hook formation in Arabidopsis. Plant Cell 26, 1105-1117.
  1. Zhong Shangwei, Shi Hui, Xue Chang, Wei Ning, Guo Hongwei*, and Deng Xing Wang*(2014). Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proceedings of the National Academy of Sciences of the United States of America 111, 3913-3920.
  1. Li Zhonghai, Zhao Yi, Liu Xiaochuan, Peng Jinying, Guo Hongwei*, and Luo Jingchu*(2014). LSD 2.0: an update of the leaf senescence database. Nucleic Acids Research 42, D1200-D1205.

2013:

  1. Li Zhonghai, Peng Jinying, Wen Xing, and Guo Hongwei*(2013). ETHYLENE-INSENSITIVE3 is a senescence-associated gene that accelerates age-dependent leaf senescence by directly repressing miR164 transcription in Arabidopsis. Plant Cell 25, 3311-3328.
  1. Zhang Xinyan, Chen Yutao, Lin Xin, Hong Xinyu, Zhu Ying, Li Wenyang, He Wenrong, An Fengying, and Guo Hongwei*(2013). Adenine phosphoribosyl transferase 1 is a key enzyme catalyzing cytokinin conversion from nucleobases to nucleotides in Arabidopsis. Molecular Plant 6, 1661-1672.
  1. Song Susheng, Qi Tiancong, Fan Meng, Zhang Xing, Gao Hua, Huang Huang, Wu Dewei, Guo Hongwei, and Xie Daoxin*(2013). The bHLH subgroup IIId factors negatively regulate jasmonate-mediated plant defense and development. Plos Genetics 9(7):e1003653.
  1. Ji Yusi, and Guo Hongwei*(2013). From endoplasmic reticulum (ER) to nucleus: EIN2 bridges the gap in ethylene signaling. Molecular Plant 6, 11-14.
  1. Zheng Dongchao, Han Xiao, An Yi, Guo Hongwei, Xia Xinli*, and Yin Weilun*(2013). The nitrate transporter NRT2.1 functions in the ethylene response to nitrate deficiency in Arabidopsis. Plant Cell and Environment 36, 1328-1337.
  1. Li Hongjiang, Xu Tongda, Lin Deshu, Wen Mingzhang, Xie Mingtang, Duclercq Jerome, Bielach Agnieszka, Kim Jungmook, Reddy G. Venugopala, Zuo Jianru, Benkova Eva, Friml Jiri, Guo Hongwei, and Yang Zhenbiao*(2013). Cytokinin signaling regulates pavement cell morphogenesis in Arabidopsis. Cell Research 23, 290-299.
  1. Kim Hye Gi, Kwon Sun Jae, Jang Young Jin, Nam Myung Hee, Chung Joo Hee, Na Yun-Cheol, Guo Hongwei, and Park Ohkmae K.*(2013). GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiology 163, 1776-1791.

2012:

  1. Wen Xing, Zhang Cunli, Ji Yusi, Zhao Qiong, He Wenrong, An Fengying, Jiang Liwen, and Guo Hongwei*(2012). Activation of ethylene signaling is mediated by nuclear translocation of the cleaved EIN2 carboxyl terminus. Cell Research 22, 1613-1616.
  1. Wang Qin, Fristedt Rikard, Yu Xuhong, Chen Zugen, Liu Hongtao, Lee Yurhee, Guo Hongwei, Merchant Sabeeha S., and Lin Chentao*(2012).The γ-carbonic anhydrasesubcomplex of mitochondrial complex I is essential for development and important for photomorphogenesis of Arabidopsis. Plant Physiology 160, 1373-1383.
  1. Zhong Shangwei, Shi Hui, Xue Chang, Wang Lei, Xi Yanpeng, Li Jigang, Quail Peter H., Deng Xing Wang*, and Guo Hongwei*(2012). A molecular framework of light-controlled phytohormone action in Arabidopsis. Current Biology 22, 1530-1535.
  1. Men Yongfan, Yu Qiang, Chen Zitian, Wang Jianbin, Huang Yanyi*, and Guo Hongwei*(2012). A high-throughput imaging system to quantitatively analyze the growth dynamics of plant seedlings. Integrative Biology 4, 945-952.
  1. Shi Yiting, Tian Shouwei, Hou Lingyan, Huang Xiaozhen, Zhang Xiaoyan, Guo Hongwei, and Yang Shuhua*(2012). Ethylene signaling negatively regulates freezing tolerance by repressing expression of CBF and Type-A ARR genes in Arabidopsis. Plant Cell 24, 2578-2595.
  1. Li Zhonghai, Peng Jinying, Wen Xing, and Guo Hongwei*(2012). Gene network analysis and functional studies of senescence-associated genes reveal novel regulators of Arabidopsisleaf senescence. Journal of Integrative Plant Biology 54, 526-539.
  1. An Fengying, Zhang Xing, Zhu Ziqiang, Ji Yusi, He Wenrong, Jiang Zhiqiang, Li Mingzhe, and Guo Hongwei*(2012). Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsisseedlings. Cell Research 22, 915-927.
  1. Zhu Ziqiang, An Fengying, Feng Ying, Li Pengpeng, Xue Li, Mu A., Jiang Zhiqiang, Kim Jong-Myong, To Taiko Kim, Li Wei, Zhang Xinyan, Yu Qiang, Dong Zhi, Chen Wen-Qian, Seki Motoaki, Zhou Jian-Min, and Guo Hongwei*(2011). Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 108, 12539-12544.

2011:

  1. He Wenrong, Brumos Javier, Li Hongjiang, Ji Yusi, Ke Meng, Gong Xinqi, Zeng Qinglong, Li Wenyang, Zhang Xinyan, An Fengying, Wen Xing, Li Pengpeng, Chu Jinfang, Sun Xiaohong, Yan Cunyu, Yan Nieng, Xie De-Yu, Raikhel Natasha, Yang Zhenbiao, Stepanova Anna N., Alonso Jose M., and Guo Hongwei*(2011). A small-molecule screen identifies L-Kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth inArabidopsis. Plant Cell 23, 3944-3960.
  1. Stepanova Anna N., Yun Jeonga, Robles Linda M., Novak Ondrej, He Wenrong, Guo Hongwei, Ljung Karin, and Alonso Jose M.*(2011). The ArabidopsisYUCCA1 flavin monooxygenase functions in the Indole-3-Pyruvic acid branch of auxin biosynthesis. Plant Cell 23, 3961-3973.
  1. Zhao Qiong, and Guo Hongwei*(2011). Paradigms and paradox in the ethylene signaling pathway and interaction network. Molecular Plant 4, 626-634.
  1. Li Hongjiang, Lin Deshu, Dhonukshe Pankaj, Nagawa Shingo, Chen Dandan, Friml Jiri, Scheres Ben, Guo Hongwei, and Yang Zhenbiao*(2011). Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsisleaf epidermis. Cell Research 21, 970-978.
  1. Jiang Zhiqiang, Liu Xiaochuan, Peng Zhiyu, Wan Yinan, Ji Yusi, He Wenrong, Wan Wen, Luo Jingchu*, and Guo Hongwei*(2011). AHD2.0: an update version of ArabidopsisHormone Database for plant systematic studies. Nucleic Acids Research 39, D1123-D1129.
  1. Liu Xiaochuan, Li Zhonghai, Jiang Zhiqiang, Zhao Yi, Peng Jinying, Jin Jinpu, Guo Hongwei*, and Luo Jingchu*(2011). LSD: a leaf senescence database. Nucleic Acids Research 39, D1103-D1107.

2010:

  1. An Fengying, Zhao Qiong, Ji Yusi, Li Wenyang, Jiang Zhiqiang, Yu Xiangchun, Zhang Chen, Han Ying, He Wenrong, Liu Yidong, Zhang Shuqun, Ecker Joseph R., and Guo Hongwei*(2010). Ethylene-induced stabilization of ETHYLENE INSENSITIVE3 and EIN3-LIKE1 is mediated by Proteasomal degradation of EIN3 binding F-Box 1 and 2 that requires EIN2 in Arabidopsis. Plant Cell 22, 2384-2401.
  1. Jiang Zhiqiang, and Guo Hongwei*(2010). A comparative genomic analysis of plant hormone related genes in different species. Journal of Genetics and Genomics 37, 219-230.
  1. Zhong Shangwei, Shi Hui, Xi Yanpeng, and Guo Hongwei*(2010). Ethylene is crucial for cotyledon greening and seedling survival during de-etiolation. Plant Signaling & Behavior 5, 739-742.

2009:

  1. Zhong Shangwei, Zhao Mantong, Shi Tianying, Shi Hui, An Fengying, Zhao Qiong, and Guo Hongwei*(2009). EIN3/EIL1 cooperate with PIF1 to prevent photo-oxidation and to promote greening of Arabidopsisseedlings. Proceedings of the National Academy of Sciences of the United States of America 106, 21431-21436.
  1. Peng Zhi-yu, Zhou Xin, Li Linchuan, Yu Xiangchun, Li Hongjiang, Jiang Zhiqiang, Cao Guangyu, Bai Mingyi, Wang Xingchun, Jiang Caifu, Lu Haibin, Hou Xianhui, Qu Lijia, Wang Zhiyong, Zuo Jianru, Fu Xiangdong, Su Zhen, Li Songgang, and Guo Hongwei*(2009). ArabidopsisHormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis. Nucleic Acids Research 37, D975-D982.
  1. Chen Huamin, Xue Li, Chintamanani Satya, Germain Hugo, Lin Huiqiong, Cui Haitao, Cai Run, Zuo Jianru, Tang Xiaoyan, Li Xin, Guo Hongwei, and Zhou Jian-Min*(2009). ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 repress SALICYLIC ACID INDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity in Arabidopsis. Plant Cell 21, 2527-2540.
  1. Li Hao, Wong Wai Shing, Zhu Lin, Guo Hongwei, Ecker Joseph, and Li Ning*(2009). Phosphoproteomic analysis of ethylene-regulated protein phosphorylation in etiolated seedlings of Arabidopsismutant ein2 using two-dimensional separations coupled with a hybrid quadrupole time-of-flight mass spectrometer. Proteomics 9, 1646-1661.

2008: 

     1. Zhu Ziqiang, and Guo Hongwei* (2008). Genetic basis of ethylene perception and signal transduction in Arabidopsis. Journal of Integrative Plant Biology 50, 808-815.

2007:   

  1. Li Hongjiang, and Guo Hongwei* (2007). Molecular basis of the ethylene signaling and response pathway in Arabidopsis. Journal of Plant Growth Regulation 26, 106-117.

2006 :

  1. Olmedo Gabriela#, Guo Hongwei#, Gregory Brian D.#, Nourizadeh Saeid D.#, Aguilar-Henonin Laura, Li Hongjiang, An Fengying, Guzman Plinio, and Ecker Joseph R.*(2006). ETHYLENE-INSENSITIVE5 encodes a 5 '-> 3 ' exoribonuclease required for regulation of the EIN3-targeting F-box proteins EBF1/2. Proceedings of the National Academy of Sciences of the United States of America 103, 13286-13293.
  1. An Fengying, and Guo Hongwei*(2006). Molecular mechanism of ethylene signal transduction. Chinese Bulletin of Botany 23, 531-542.

2004 :

  1.  Guo Hongwei, and Ecker Joseph R.* (2004). The ethylene signaling pathway: new insights. Current Opinion in Plant Biology 7, 40-49.

2003:

  1.  Guo Hongwei, and Ecker Joseph R.* (2003). Plant responses to ethylene gas are mediated by SCF (EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor. Cell 115, 667-677. 

2002:

  1. Shalitin Dror, Yang Hongyun, Mockler Todd C., Maymon Maskit, Guo Hongwei, Whitelam Garry C., and Lin Chentao* (2002). Regulation of Arabidopsis cryptochrome 2 by blue-light-     dependent phosphorylation. Nature 417, 763-767.

2001:

  1. Guo Hongwei, Mockler Todd, Duong Hien, and Lin Chentao* (2001). SUB1, an Arabidopsis Ca2+-binding protein involved in cryptochrome and phytochrome coaction. Science 291, 487-490. 

1999 :

  1. Guo Hongwei, Duong Hien, Ma Nha, and Lin Chentao*(1999). The Arabidopsisblue light receptor cryptochrome 2 is a nuclear protein regulated by a blue light-dependent post-transcriptional mechanism. Plant Journal 19, 279-287. 
  1. Mockler Todd C.,Guo Hongwei, Yang Hongyun, Duong Hien, and Lin Chentao*(1999). Antagonistic actions of Arabidopsis cryptochromes and phytochrome B in the regulation of floral induction. Development 126, 2073-2082.

1998:

  1. Guo Hongwei, Yang Hongyun, Mockler Todd C., and Lin Chentao*(1998). Regulations of flowering time by Arabidopsisphotoreceptors. Science 279, 1360-1363. 
  1. Lin Chentao*, Yang Hongyun, Guo Hongwei, Mockler Todd, Chen Jeff, and Cashmore Anthony R. (1998). Enhancement of blue-light sensitivity of Arabidopsisseedlings by a blue light receptor cryptochrome 2. Proceedings of the National Academy of Sciences of the United States of America95, 2686-2690.

研究领域

植物激素信号转导

植物小RNA生物学

植物衰老与采后生物学


教学

主讲:

生物学原理

植物生理学


学术成果 查看更多

1)揭示了植物激素乙烯信号转导中一系列的分子及生化机制,在国际上率先建立了乙烯作用的蛋白降解模型和RNA降解模型;

2)揭示了乙烯与多种植物激素(生长素、茉莉素、赤霉素)以及与环境信号(光、胁迫)之间的相互作用机理;

3)报道了植物内源基因具有潜在的发生转录后基因沉默的风险,并发现了抑制内源转录后基因沉默的双保险模块,即功能冗余的两条细胞质RNA降解途径。

4)以拟南芥为模型开展了植物器官衰老调控机理研究,建立了世界上第一个植物叶片衰老数据库。同时,以重要园艺作物番茄为材料,对果实发育调控机理进行深入探索,综合利用分子遗传学,化学遗传学和系统生物学等手段,进行采后保鲜技术的研究开发。

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南科大生物系成立于2012年,在短短7年多时间里,吸引了一批海内外高尖端人才加盟,已初步建成了以资深教授领军,科研活跃和发展势头强劲的副教授为中坚力量,年轻助理教授为前锋的一支国际化高水平的教研序列队伍。生物系引进的教授序列全部具有博士学位,毕业于国际一流大学,在海外知名大学或研究机构从事过博士后研究,或在国际一流大学获得教职。其中的资深教授在加入南科大之前已经在境外著名高校或科研机构获得了终身教授的职位。此外,南方科技大学生物系还吸引了以年轻的博士、博士后组成的工程师团队辅助教学和科研工作的展开。教学与科研辅助人员逾300人。研究方向涵盖分子细胞生物学、神经生物学、植物生物学、系统生物学、结构生物学等领域,侧重生命科学前沿领域的基础研究以及与生命科学相关的应用基础研究,积极鼓励学科交叉。
植物学方向依托植物与食品联合研究所,面向国家农业重大战略需求,重点开展植物科学以及相关交叉领域的前沿研究。该方向由18位学术表现卓越的中青年科学家组成,专业方向完整、学科优势互补。利用设施完善和品类丰富的科研平台,包括表型动态分析平台,细胞影像平台、小分子筛选平台,温室种植平台等,开展细胞信号转导、基因表达调控、蛋白结构解析、细胞分化与发育分子机制方面的基础和应用研究,以及建立分子育种与绿色生物合成理论和技术体系。
在教学方面,开设了生物科学、生物技术和物信息三个本科专业。生物科学和生物技术是生命科学的基础专业,生物信息为交叉专业。为与国际接轨,生物系一直以来从多层次,多渠道致力于提高南科大学生的科研水平,提升南科大的国际知名度。在教学中坚持骨干教授在教学一线讲课,广泛采用国际先进的英文原版教材,中英双语授课。积极鼓励学生进入教授实验室参与科研项目的研究或竞赛,发挥学生学习的主动性,加强创新思维和技能训练。2016年,我系生物学学科,入选广东省高优势重点学科。
生物系3名本科生在导师指导下,以第一作者在SCI高水平科研刊物上发表论文。本学科还积极鼓励学生参加各种竞赛等活动,已连续六年(2012-2018)指导学生组队参加国际基因工程机器设计竞赛(International Genetically Engineered Machine Competition, iGEM)并获得四金四银的出色成绩。同时本科生有十余项代表我校大学生创新、创业训练计划的项目获批。在多渠道培养创新人才方面,我校已与英国爱丁堡大学、美国天普大学、丹麦哥本哈根大学、美国德州医学健康中心等世界一流大学签署了学生合作培养的合作协议MOU,为本学科的教学、科研和教育体系创新提供宽大的国际舞台和视野。
2016—2019届毕业生中,已有多名学生获得境外优秀高校深造的机会,包括常青藤盟校——美国康奈尔大学及约翰霍普金斯大学,纽约大学、圣路易斯华盛顿大学、西雅图华盛顿大学、德国哥廷根大学、香港科技大学、新加坡南洋理工大学等世界顶尖学府的入学橄榄枝。另有进入知名上市企业或机构,包括华为、华大基因和邦德教育等。
生命科学已成为21世纪自然科学的重要学科。生命科学的发展关乎生命健康和民生幸福。如今,生物和健康产业已成为推动世界经济发展的新动力,亦是深圳市重点培育的战略性新兴产业, 前沿生命科学的发现是生物和健康产业发展的基础。生物系以创建国际先进的教学科研基地为奋斗目标,培养拔尖创新人才和科学研究为己任,力争在科研成果、人才培养、队伍建设、学科建设和科技产业化等方面实现快速发展。未来,生物系将以国际视野,基于时代发展需求凝练学科发展方向,鼓励交叉学科专业发展,注重原创性研究和研发应用并重,将创造具有国际影响力的研究、技术和产品,培养引领学科发展的国际领军尖端人才,为生物产业发展培养创新型人才,为地区、国家乃至全球生命科学和健康经济产业发展提供知识创新和技术支持的平台和支撑,促进人类健康和社会经济的发展。诚望有志之士踊跃加盟,共创辉煌!
 
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