Professor |School of Medicine   Research Group

Dr. Jinsong Bian is a full Professor in the Department of Pharmacology, School of Medicine, Southern University of Science and Technology. He earned his PhD degree from the University of Hong Kong and was awarded the Dr KP Stephen Chang Gold Medal for outstanding performance in the degree of Doctor of Philosophy in 2000. Dr Bian then went on to complete his post-doctoral training under an American Heart Association Fellowship at the Albert Einstein College of Medicine in New York, USA in 2003. After completion of the post-doctoral training, Dr. Bian started his teaching and research work in the National University of Singapore as an Associate Professor (with Tenure) from October 2003 to April 2020.

Dr Bian is an Associate Editor, lead guest editor and reviewing editor of 13 international journals, including Antioxidant Redox Signalling, Journal of Alzheimer’s Disease, Frontiers in Pharmacology. He has served as a panel member of the Singapore National Medical Research Council (since 2007) and is also a consultant Member of the Greece Society of Studying Cardiovascular Diseases (SOS-CVD) (since 2010). He serves as an advisory committee member of different societies or conferences, including the International and European Conferences on the Biology of Hydrogen Sulphide, and the Asian Society for Vascular Biology (ASVB). He has published over 120 papers in international journals including Cir Res, PNAS, JASN, Redox Biology, and has delivered over 70 lectures at the invitation of international and regional scientific societies, institutes and conference organizers.

Personal Profile

Research

1). Biology of endogenous mediators (e.g. hydrogen sulfide)

2). Novel functions of Na+/K+ ATPase


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Recent publications:

1. Sun HJ, Cao L, Zhu MY, Wu ZY, Shen CY, Nie XW, Bian JS*. DR-region of Na+/K+-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice. Theranostics, 2020, Accepted.

2. Zhu M, Cao L, Xiong S, Sun H, Wu Z, Bian JS. Na+/K+-ATPase-dependent autophagy protects brain against ischemic injury. Signal Transduction and Targeted Therapy. 2020, Accepted.

3. Sun HJ, Xiong SP, Wu ZY, Cao L, Zhu MY, Moore PK, Bian JS. Induction of caveolin 3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy. Redox Biology, 2020, Mar 5;32:101493. doi: 10.1016

4. Sun HJ, Lee WT, Leng B, Wu ZY, Yang Y, Bian JS. Nitroxyl as a Potential Theranostic in the Cancer Arena. Antioxid Redox Signal. 2020 Feb 10;32(5):331-349. doi: 10.1089/ars.2019.7904.

5. Cao X, Ding L, Xie ZZ, Yang Y, Whiteman M, Moore PK, Bian JS. A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? Antioxid Redox Signal. 2019 Jul 1;31(1):1-38.

6. Shi M, Cao L, Cao X, Zhu M, Zhang X, Wu Z, Xiong S, Xie Z, Yang Y, Chen J, Wong PTH, Bian JS. DR-region of Na+/K+ ATPase is a target to treat excitotoxicity and stroke. Cell Death Dis. 2018 Dec 18;10(1):6. doi: 10.1038/s41419-018-1230-5.

7. Cao X, Nie X, Xiong S, Cao L, Wu Z, Moore PK, Bian JS. Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity. Redox Biology, 2018 May;15:513-521.

8. Cao L, Cao X, Zhou Y, Vijay NB, Wu ZY, Hu LF, Yang Y, Sethi G, Moore PK, Bian JS. Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ1-42 synthesis by suppressing the activation of STAT3 and cathepsin S. Brain Behav Immun. 2018 Oct;73:603-614.

9. Cao X, Xiong S, Zhou Y, Wu ZY, Ding L, Zhu Y, Wood M, Whiteman M, Moore PK, Bian JS. Renal protective effect of hydrogen sulfide in cisplatin-induced nephrotoxicity. Antioxid Redox Signal. 2018 Jan 9. doi: 10.1089/ars.2017.7157. [Epub ahead of print]

10. Nie X, Tan J, Dai Y, Liu Y, Zou J, Sun J, Ye S, Shen C, Fan L, Chen J, Bian JS. CCL5 deficiency rescues pulmonary vascular dysfunction, and reverses pulmonary hypertension via caveolin-1-dependent BMPR2 activation. J Mol Cell Cardiol. 2018 Mar;116:41-56

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Contact Address

Department of Pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518055, Guangdong,China.

Office Phone

Email

bianjs@sustech.edu.cn

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