• Journal Papers

61.Zhong-Liang Li,† Gui-Chun Fang,† Qiang-Shuai Gu † and Xin-Yuan Liu *  ''Recent advances in copper-catalysed radical-involved asymmetric 1,2-difunctionalization of alkenes'' Chem. Soc. Rev. 2020, 4932

60. Liu Ye+, Yu Tian+, Xiang Meng, Qiang-Shuai Gu and Xin-Yuan Liu*  ''Cu(I)/Chiral Phosphoric Acid-Catalyzed Radical-Involved Enantioselective Intramolecular Amination of Allylic and Benzylic C–H Bonds'' Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.201911742

59. Xiao-Yang Dong+, Yu-Feng Zhang+, Can-Liang Ma+, Qiang-Shuai Gu+, Fu-Li Wang+, Zhong-Liang Li, Sheng-Peng Jiang and Xin-Yuan Liu * "A general asymmetric copper-catalysed Sonogashira C(sp3)–C(sp) coupling" Nature Chemistry 2019, DOI: 10.1038/s41557-019-0346-2.

58. Qiang-Shuai Gu, Zhong-Liang Li, and Xin-Yuan Liu* "Copper(I)-Catalyzed Asymmetric Reactions Involving Radicals" Acc. Chem. Res. 2019 DOI:10.1021/acs.accounts.9b00381.

57. Jin-Shun Lin, Tao-Tao Li, Ji-Ren Liu, Guan-Yuan Jiao, Qiang-Shuai Gu, Jiang-Tao Cheng, Yu-Long Guo, Xin Hong*, and Xin-Yuan Liu*, "Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Three-Component Radical-Initiated 1,2-Dicarbofunctionalization of Alkenes." J. Am. Chem. Soc. 2019, 141, 1074.

56. Jin-Shun Lin, Tao-Tao Li, Guan-Yuan Jiao, Qiang-Shuai Gu, Jiang-Tao Cheng, Ling Lv, and Xin-Yuan Liu*, "Chiral Brønsted Acid‐Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes." Angew. Chem. Int. Ed. 201958, 7092.

55. Yang Zeng, Xiao-Dong Liu, Xian-Qi Guo, Qiang-Shuai Gu*, Zhong-Liang Li*, Xiao-Yong Chang & Xin-Yuan Liu* "Cu/Chiral Phosphoric Acid-Catalyzed Radical-Initiated Asymmetric Aminosilylation of Alkene with Hydrosilane" SCIENCE CHINA Chemistry 201962, doi: 10.1007/s11426-019-9528-2.

54. Gui‑Chun Fang, Yong‑Feng Cheng, Zhang‑Long Yu, Zhong‑Liang Li, Xin‑Yuan Liu,"Recent Advances in First‑Row Transition Metal/Chiral Phosphoric Acid Combined Catalysis." Top. Curr. Chem. 2019377, 23.

53. Na Wang, Qiang-Shuai Gu, Zhong-Liang Li, Zhuang Li, Yu-Long Guo, Zhen Guo, and Xin-Yuan Liu*, "Direct Photocatalytic Synthesis of Medium-Sized Lactams through C–C Bond Cleavage." Angew. Chem. Int. Ed. 201857, 14225.

52. Xi-Tao Li, Qiang-Shuai Gu, Xiao-Yang Dong, Xiang Meng, and Xin-Yuan Liu*, "Cinchona Alkaloid‐Based Sulfonamide/Copper Catalyst for Asymmetric Radical Oxytrifluoromethylation of Alkenyl Oximes." Angew. Chem. Int. Ed. 2018, 57, 7668.

51. Liu Ye, Qiang-Shuai Gu, Guo-Cong Chen, and Xin-Yuan Liu,* "Construction of Bicyclo[3.1.0]hexanes Containing Vicinal All-Carbon Quaternary Stereocenters via Radical Asymmetric Intramolecular α-Cyclopropanation of Aldehydes." Nat. Commun. 2018, 9, 227.

50. Jin-Hao Zhao, Yong Yang, Jin-Xin Che, Jun Zuo, Xiao-Hua Li, Yong-Zhou Hu, Xiao-Wu Dong,* Liang Gao,* and Xin-Yuan Liu*, “Compartmentalization of Incompatible Polymers within Metal–Organic Frameworks towards Homogenization of Heterogeneous Hybrid Catalysts for Tandem Reactions.” Chem. Eur. J. 201824, 9903. 

49. Na Wang, Jian Wang, Yu-Long Guo, Lei Li, Yan Sun, Zhuang Li, Hong-Xia Zhang, Zhen Guo, Zhong-Liang Li* and Xin-Yuan Liu *, “Oximinotrifluoromethylation of unactivated alkenes under ambient conditions.” Chem. Commun2018, 54, 8885.

48. Na Wang, Liu Ye, Zhong-Liang Li, Lei Li, Zhuang Li, Hong-Xia Zhang, Zhen Guo, QiangShuai Gu* and Xin-Yuan Liu*, “Hydrofunctionalization of Alkenols Triggered by Addition of Diverse Radicals to Unactivated Alkenes and Subsequent Remote Hydrogen Atom Translocation.” Org. Chem. Front20185, 2810.

47. Xiao-Wu Dong*, Yong Yang, Jin-Xin Che, Jun Zuo, Xiao-Hua Li, Liang Gao, Yong-Zhou Hu and Xin-Yuan Liu*, “Heterogenization of homogeneous chiral polymers in metal–organic frameworks with enhanced catalytic performance for asymmetric catalysis.” Green Chem. 201820, 4085.

46. Xi-Tao Li, Ling Lv, Qiang-Shuai Gu,*, and Xin-Yuan Liu*, “Copper-catalyzed radical oxytrifluoromethylation of alkenyl oximes at ambient temperature.” Tetrahedron201874, 6041.

45. Yu Tian, Su Chen, Qiang-Shuai Gu, Jin-Shun Lin, Xin-Yuan Liu*, “Amino- and azidotrifluoromehtylation of alkenes.” Tetrahedron Lett. 201859, 203. (Invited Digest)

44. Na Wang, Qiang-Shuai Gu*, Yong-Feng Cheng, Lei Li, Zhong-Liang Li, Zhen Guo*, and Xin-Yuan Liu*, “Visible-Light Promoted Preparation of Trifluoromethylated Tetrahydrofuran and Tetrahydropyran.” Chin. J. Org. Chem201939, 200.

43. Xue-Fei Li, Jin-Shun Lin, Jian Wang, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu*, “Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Radical- Initiated Aminoarylation of Alkenes.” Acta Chim. Sinica 201876, 878.

42. Fu-Li Wang, Xiao-Yang Dong, Jin-Shun Lin, Yang Zeng, Guan-Yuan Jiao, Qiang-Shuai Gu, Xian-Qi Guo, and Xin-Yuan Liu*, “Catalytic Asymmetric Diamination of Unactivated Alkene with Dialkylaminyl Radical” Chem 20173, 979.

41. Lei Li, Zhong-Liang Li, Qiang-Shuai Gu, Na Wang, Xin-Yuan Liu,* "A Remote Radical Vinyl Migration Strategy to Access Medium- and Large-sized Cyclic Alkenes" Sci. Adv. 20173, e1701487.

40. Lei Li, Liu Ye, Shao-Fei Ni, Zhong-Liang Li, Su Chen, Yi-Meng Du, Xiao-Hua Li, Li Dang* and Xin-Yuan Liu,* "Phosphine-catalyzed remote α-C–H bond activation of alcohols or amines triggered by the radical trifluoromethylation of alkenes: reaction development and mechanistic insights" Org. Chem. Front. 20174, 2139.

39. Xue-Fei Li, Jin-Shun Lin and Xin-Yuan Liu,* “Catalytic Radical Intramolecular Aminoperfluoroalkylation and Aminodifluoromethylation of Unactivated Alkenes with Fluoroalkylsulfonyl Chlorides” Synthesis 2017, 49, 4213.
Published as part of the Special Topic Modern Cyclization Strategies in Synthesis

38. Jin-Shun Lin, Fu-Li Wang, Xiao-Yang Dong, Wei-Wei He, Yue Yuan, Su Chen, and Xin-Yuan Liu,* "Catalytic Asymmetric Radical Aminoperfluoroalkylation and Aminodifluoromethylation of Alkenes: A Versatile Platform for Enantioenriched-Fluoroalkyl Amines" Nat. Commun. 20178, 14841.

37. Yong-Feng Cheng, Xiao-Yang Dong, Qiang-Shuai Gu, Zhang-Long Yu, and Xin-Yuan Liu* “Achiral Pyridine Ligand-Enabled Enantioselective Radical Oxytrifluoromethylation of Alkenes with Alcohols” Angew. Chem., Int. Ed. 2017, 56, 8883.
Selected as Cover pictures.
Highlighted by Synfacts 201713(10), 1042.

36 Taotao Li, Peng Yu, Yi-Meng Du, Jin-Shun Lin, Yonggang Zhi,* and Xin-Yuan Liu,* "Dual-Catalyzed Enantioselective Remote C−H Functionalization Triggered by Radical Trifluoromethylation of Alkenes: Highly Selective Formation of C−CF3 and C−C Bonds" J. Fluorine Chem2017203, 210. (invited paper for a special issue).

35 Lei Li, Qiang-Shuai Gu, Na Wang, Ping Song, Zhong-Liang Li, Xiao-Hua Li, Fu-Li Wang, and Xin-Yuan Liu,* "1,2-Difunctionalization-Type (Hetero)arylation of Unactivated Alkenes Triggered by Radical Addition/Remote (Hetero)aryl Migration" Chem. Commun201753, 4038.

34. Ping Song, Peng Yu, Jin-Shun Lin, Yiqun Li,* Ning-Yuan Yang, and Xin-Yuan Liu,* "Transition-Metal-Free β C−H Bond Carbonylation of Enamides or Amides with a Trifluoromethyl Group as CO Surrogate for the Synthesis of 1,3-Oxazin-6-ones" Org. Lett. 201719, 1330.

33. Lei Li, Zhong-Liang Li, Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, and Xin-Yuan Liu,* "Radical Aryl Migration Enables Diversity-Oriented Synthesis of Structurally Diverse Medium/Macro- or Bridged-Rings" Nat. Commun20167, 13852.

32. Zhong-Liang Li, Xiao-Hua Li, Na Wang, Ning-Yuan Yang, and Xin-Yuan Liu,* "Radical-Mediated 1,2-Formyl/carbonyl-Functionalization of Alkenes and Application to Construction of Medium-Sized-, Fused-, and Bridged-Ring Systems" Angew. Chem., Int. Ed. 2016, 55, 15100.

31. Jin-Shun Lin, Xiao-Yang Dong, Tao-Tao Li, Na-Chuan Jiang, Bin Tan, and Xin-Yuan Liu,* "A Dual-Catalytic Strategy to Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes" J. Am. Chem. Soc. 2016138, 9357.
Highlighted by “Synfacts 2016, 1020”. Highlighted by “Chin. J. Org. Chem201636, 2247”.

30. Lin Huang, Liu Ye, Xiao-Hua Li, Zhong-Liang Li, Jin-Shun Lin, and Xin-Yuan Liu,* "Stereoselective Radical Cyclization Cascades Triggered by Addition of Diverse Radicals to Alkynes to Construct 6(5)‐6‐5 Fused Rings" Org. Lett., 201618, 5284.

29. Na Wang, Lei Li, Zhong-Liang Li, Ning-Yuan Yang, Zhen Guo,* Hong-Xia Zhang, and Xin-Yuan Liu,* "Catalytic Diverse Radical-Mediated 1,2-Cyanofunctionalization of Unactivated Alkenes via Synergistic Remote Cyano Migration and Protected Strategies" Org. Lett.201618, 6026.

28. Ning-Yuan Yang, Zhong-Liang Li, Liu Ye, Bin Tan, and Xin-Yuan Liu,* "Organic base-catalysed solvent-tuned chemoselective carbotrifluoromethylation and oxytrifluoromethylation of unactivated alkenes" Chem. Commun., 2016, 52, 9052.
From themed collection 2016 Emerging Investigators by Chem. Commun.

27. Xiao-Long Yu, Liping Kuang, Su Chen, Xiao-Long Zhu, Zhong-Liang Li, Bin Tan, and Xin-Yuan Liu,* "Counteranion-Controlled Unprecedented Diastereo- and Enantioselective Tandem Povarov Reaction for Construction of Bioactive Octahydro-dipyrroloquinolines" ACS Catal. 2016, 6, 6182.

26. Na Wang, Sheng-Cai Zheng, Lin-Lin Zhang, Zhen Guo,* and Xin-Yuan Liu* "Nickel(0)-Catalyzed Denitrogenative Transannulation of Triazoles with Alkynes: Mechanistic Insights of Chemical Reactivity, Regio- and Enantioselectivity from Density Functional Theory and Experiment" ACS Catal. 20166, 3496.

25. Taotao Li, Peng Yu, Jin-Shun Lin, Yonggang Zhi,* and Xin-Yuan Liu,* "Copper-Catalyzed Redox-Triggered Remote C–H Functionalization: Highly Selective Formation of C–CF3 and C–O Bonds" Chin. J. Chem201634, 490.
Invited paper for the Special Issue of “Trifluoromethylation and Trifluoromethythiolation Reactions”

24. Can-Liang Ma, Xiao-Hua Li, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong,* Bin Tan,* and Xin-Yuan Liu,* "Gold-catalyzed tandem synthesis of bioactive spiro-dipyrroloquinolines and its application in the one-step synthesis of incargranine B aglycone and seneciobipyrrolidine (I)" Org. Chem. Front20163, 324.
From themed collection 2015 Emerging Investigators by OCF.

23. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* and Xin-Yuan Liu,* "Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation" Angew. Chem., Int. Ed. 201554, 9528.
Highlighted by “Synfacts 201511, 1029”.

22. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* and Xin-Yuan Liu,* "Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter" Angew. Chem., Int. Ed. 2015, 54, 7847.
Highlighted by “Chin. J. Org. Chem. 201535, 1802”.

21. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* and Xin-Yuan Liu,* "Phosphine-Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles" Angew. Chem., Int. Ed2015, 54, 4041.
Selected for a Cover Picture.

20. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Enantioselective C–H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene" Angew. Chem., Int. Ed. 2014, 53, 11890.
Highlighted by “Synfacts 201410, 1281”. Highlighted by “Angew. Chem., Int. Ed201756, 49”.

19. Ji-Wei Zhang, Jin-Hui Xu, Dao-Juan Cheng, Chuan Shi, Xin-Yuan Liu,* and Bin Tan,* "Discovery and Enantiocontrol of Axially Chiral Urazoles via Organocatalytic Tyrosine Click Reaction" Nat. Commun20167, 10677.

18. Jian Zhang, Shao-Xia Lin, Dao-Juan Cheng, Xin-Yuan Liu,* and Bin Tan,* "Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction" J. Am. Chem. Soc. 2015137, 14039.
Highlighted by “Synfacts  201612, 86”.

17. Ye-Hui Chen, Dao-Juan Cheng, Jian Zhang, Yong Wang, Xin-Yuan Liu,* Bin Tan,* "Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2 Naphthols" J. Am. Chem. Soc. 2015137, 15062.

16. Ming-Yue Wu, Wei-Wei He, Xin-Yuan Liu,* and Bin Tan,* "Asymmetric Construction of Spirooxindoles via Organocatalytic Multicomponent Reactions of Diazooxindoles" Angew. Chem., Int. Ed. 2015, 54, 9409.

15. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan,* "Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid" Angew. Chem., Int. Ed. 201453, 3684.
Highlighted by “Synfacts 2014, 10, 530”.

14. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu,* "Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluoromethyl γ-Lactam and Spirobenzofuranone-lactam" ACS Catal. 20155, 2826.

13. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu,* "Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes" Org. Lett2015, 17, 1589.

12. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu,* "Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form Carbon–Heteroatom/Carbon Bonds" Chem. Eur. J201521, 6718.

11. Can-Liang Ma, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong, Bin Tan,* and Xin-Yuan Liu,* "Platinum-Catalyzed Tandem Cyclization Reaction to Multiply Substituted Indolines under Microwave-Assisted Conditions" Adv. Synth. Catal. 2015357, 569.

10. Lei Li, Jing-Yao Guo, Xing-Guo Liu, Su Chen, Yong Wang, Bin Tan,* and Xin-Yuan Liu,* "Amide Groups Switch Selectivity: C–H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation" Org. Lett.201416, 6032.

9. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan,* and Xin-Yuan Liu,* “Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles" J. Org. Chem201479, 7084.

8. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu,* and Bin Tan,* "In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles" Org. Lett201416, 2192.
Highlighted by “Synfacts 201410, 754”.

7. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Direct Access to α-CF3-enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement" Org. Lett. 2014, 16, 1000.
This work is highlighted on the website

6. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan,* and Xin-Yuan Liu,* "Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles" Org. Lett201416, 504.

5. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Efficient Copper-Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse Nitrogen-Based Nucleophiles" Chem. Eur. J201420, 1332.

4. Tao Liu, Da-Qiang Li, Si-Yu Wang Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che, "Straightforward Installation of Carbon-Halogen, Carbon-Oxygen and Carbon-Carbon Bonds within Metal–Organic Frameworks via Direct C–H Functionalization" Chem. Commun., 201450, 13261.
Highlighted by “Synfacts 201410, 1272”.

3. Tao Liu, Jin-Xin Che, Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che "Alkenyl/thiol-derived Metal–Organic Frameworks via Post-Synthetic Modification for Effective Mercury Adsorption" Chem. Eur. J. 201420,14090.

2. Xiao-Wu Dong, Tao Liu, Yong-Zhou Hu,* Xin-Yuan Liu,* and Chi-Ming Che "Urea Postmodified in Metal-Organic Framework as Catalytically Active Hydrogen-Bond-Donating Heterogeneous Catalyst" Chem. Commun., 201349, 7681.
Highlighted with a front cover in Chem. Commun.;
Selected as one of HOT Chem. Comm. articles for May;
Highlighted by “Synfacts 20139, 1251”.

1. Gaosheng Yang,* Chongrong Luo, Xiaolong Mu, Tingting Wang, and Xin-Yuan Liu,* "Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas" Chem. Commun201248, 5880.

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